Ask the Experts
Polio
What is the routine schedule for giving IPV to children?
Four doses of polio vaccine (IPV) are routinely recommended for U.S. children at ages 2 months, 4 months, 6-18 months, and 4-6 years. The first dose may be given as early as age 6 weeks. If dose #3 is given after the 4th birthday, dose #4 is not needed unless mandated by the state health department for school entry.
What is the schedule for older children who have not completed their IPV series?
The schedule for polio vaccination for unvaccinated or undervaccinated older children through age 17 years is 2 doses of IPV separated by 4–8 weeks, and a third dose 6–12 months after the second dose. If an accelerated schedule is needed, three doses separated by at least 4 weeks may be given. Polio vaccine is not routinely administered to persons 18 years of age and older.
Should adults get vaccinated against polio?
Routine vaccination of persons 18 years of age and older against polio is not necessary because most adults are already immune and also have little risk of being exposed to wild polio virus.
Certain adults are at increased risk of infection, including travelers to areas were polio is common, laboratory workers who handle specimens that might contain polioviruses, and healthcare workers in close contact with patients who might be excreting wild polioviruses in their stool (such as those caring for recent immigrants from central Africa or parts of Asia).
If an adult is at increased risk of exposure and has never been vaccinated against polio, he or she should receive three doses of IPV, the first two doses given 1-2 months apart, and the third 6-12 months after the second. If time will not allow the completion of this schedule, a more accelerated schedule is possible (each dose separated four weeks from the previous dose).
If an adult at risk previously received only one or two doses of polio vaccine (either OPV or IPV), he or she should receive the remaining dose(s) of IPV, regardless of the interval since the last dose.
If an adult at increased risk previously completed a primary course of polio vaccine (three or more doses of either OPV or IPV), he or she may be given another dose of IPV to ensure protection. Only one "booster" dose of polio vaccine in a person's lifetime is recommended. It is not necessary to receive a booster dose each time a person travels to an area where polio may still occur.
A 4-year-old's vaccine records show that she had 4 IPVs, given at 2m, 4m, 6m, and age 2. Should she have a booster dose?
Seroconversion rates following 3 doses of IPV at 2, 4, and 6 months of age are 99–100% for all three polio vaccine viruses. A "booster" dose is usually recommended at school entry (4-6 years of age), mainly to assure long-term protection. From the standpoint of protection it isn't necessary to give a fifth dose of IPV to a child who received 4 doses before 2 years of age. However, many states mandate a dose of polio vaccine to be administered on or after 4 years of age as a requirement for school entry. In this situation just give a fifth dose at school entry. There is no harm in giving an additional dose.

Is it true that IPV can be given either SC or IM?
Yes.
What is the risk of serious reactions following IPV?
There are no severe reactions known to occur following IPV.
Reviewed on 4/07
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