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Ask the Experts: HPV (Human Papillomavirus): Contraindications & Precautions

Results (4)

Contraindications are the following:

  • HPV vaccine is contraindicated for persons with a history of immediate hypersensitivity to any vaccine component, including yeast.
  • The precaution to HPV vaccine is a moderate or severe acute illness with or without fever. Vaccination should be deferred until the condition improves.

HPV vaccines are not recommended for use during pregnancy. If a person is found to be pregnant after starting the vaccination series, the remainder of the 2 or 3-dose series (depending on the age of first HPV vaccination) should be delayed until completion of pregnancy. Pregnancy testing is not needed before vaccination. If a vaccine dose has been administered during pregnancy, no intervention is needed. You can find more information about HPV vaccine and pregnancy in the ACIP recommendations at:

Last reviewed: October 13, 2023

Yes. A woman with evidence of present or past HPV infection identified through cervical screening may be vaccinated. Recipients of HPV vaccinations should be counseled that the vaccine will not have a therapeutic effect on any existing HPV infections or cervical lesions.

Last reviewed: October 13, 2023


Last reviewed: October 13, 2023

No. Even a woman found to be infected with a strain of HPV that is present in the vaccine could receive protection from the other strains in the vaccine.

Last reviewed: October 13, 2023

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