Following a multi-year shortage, in April 2021, the FDA-licensed yellow fever vaccine, YF-Vax (Sanofi) resumed availability for purchase in the United States. Providers with a current Yellow Fever Vaccination Stamp issued by their state or territorial health department may order YF-VAX from the manufacturer.
Locations that administer yellow fever vaccine can be found on CDC’s yellow fever vaccination clinic search page at wwwnc.cdc.gov/travel/yellow-fever-vaccination-clinics/search.
Healthcare providers should refer to the section titled “Yellow Fever and Malaria Information, by Country,” in CDC Health Information for International Travel 2024 (“The Yellow Book”) for information about the countries that require yellow fever vaccination for entry and the countries where CDC recommends yellow fever vaccination. If a country does not have an entry requirement, CDC does not recommend yellow fever vaccination if the traveler’s itinerary does not include travel to a yellow fever–endemic area. This section is available at wwwnc.cdc.gov/travel/yellowbook/2024/preparing/yellow-fever-vaccine-malaria-prevention-by-country.
Last reviewed:
August 21, 2023
No, Dengvaxia does not protect the recipient against yellow fever.
Last reviewed:
January 17, 2025
All vaccines except the live, replication-competent smallpox vaccine (ACAM2000, Emergent Biosolutions) and yellow fever vaccine may be given to people who are breastfeeding.
ACAM2000 is contraindicated due to the theoretical risk of contact transmission of the vaccine virus from mother to child.
The only yellow fever (YF) vaccine licensed in the United States (YF-Vax, Sanofi) is contraindicated in people who are breastfeeding infants younger than 9 months of age. There have been three case reports of YF vaccine-associated encephalitis in infants under one month of age who were being exclusively breastfed at the time the mother received YF vaccine. ACIP currently recommends that people who are breastfeeding should be advised to postpone travel to YF endemic or epidemic regions; however, if travel cannot be avoided or postponed, the breastfeeding parent should receive YF vaccine. Although there are no data, some experts recommend that breastfeeding people who receive YF vaccine should temporarily suspend breastfeeding, pump, and discard pumped milk for at least 2 weeks after vaccination before resuming breastfeeding.
Last reviewed:
August 29, 2022
Yellow fever is contraindicated for people who have a history of a severe (anaphylactic) allergy to eggs.
ACIP and CDC no longer consider egg allergy of any severity to be a contraindication or precaution to egg-based influenza vaccines. A person with egg allergy of any severity may receive any influenza vaccine that is appropriate for the person’s age and health status. When administering an egg-based influenza vaccine to a person with egg allergy of any severity, no additional safety precautions are needed, beyond those recommended when administering any vaccine to any recipient.
For more details about giving influenza vaccine to people with a history of egg allergy, go to www.cdc.gov/acip-recs/hcp/vaccine-specific/flu.html for a link to the current ACIP recommendations for influenza vaccination.
Last reviewed:
September 3, 2025
