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Ask the Experts: COVID-19: Storage & Handling

Results (2)

For the 2026–2027 season, Comirnaty manufacturer-filled syringes (MFS), mNexspike MFS, and Nuvaxovid MFS all should be stored exclusively in the refrigerator at standard vaccine storage temperatures (between 2°C and 8°C [36°F and 46°F]) until the printed expiration date.

Spikevax MFS, if received frozen and never thawed, may be stored at ordinary vaccine freezer storage temperatures (between -50°C and -15°C [-58°F and 5°F]) until the printed expiration date. Once thawed, it may be stored at standard vaccine refrigerator temperatures (above) for up to 60 days or until the expiration date (whichever comes first).

Comirnaty single dose vials (SDV) for ages 6 months through 11 years, if received frozen and never thawed, may be maintained until the printed expiration date in an ultracold freezer between -90°C and -60°C (-130°F and -76°F). Once thawed, it may be stored at standard vaccine refrigerator temperatures (above) for up to 10 weeks, or until the expiration date, whichever comes first.

For further details, refer to the specific vaccine’s package insert. Immunize.org has assembled links to key COVID-19 vaccine resources, including package inserts, in the Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools: www.immunize.org/catg.d/p3130.pdf.

Last reviewed: October 18, 2026

Although routine transportation of vaccines to different facilities is not generally recommended, there are times when this is necessary. CDC recommends transporting COVID-19 vaccine in unopened vials or manufacturer-filled syringes (MFS) and always with a continuous temperature monitoring device to ensure adherence to authorized storage times and temperatures. See the product package insert for details on permissible conditions for transport.

Last reviewed: October 18, 2026

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