What should I do if an infant tests negative for anti-HBs after 2 complete vaccine series?

Available data do not suggest a benefit from administering additional HepB vaccine doses to infants who have not attained anti-HBs of mIU/mL or higher following receipt of two complete HepB series. HBsAg-positive infants should be referred for appropriate follow-up with a physician who specializes in evaluating infants with liver disease.