Should people who are HIV positive receive pneumococcal vaccines?

Yes. People with HIV infection are at high risk of pneumococcal disease. Adults 19 and older should be vaccinated with PCV20 alone or with PCV15 followed by PPSV23 one year later. If using a combination of PCV15 followed by PPSV23, consider using a minimum interval of at least 8 weeks between doses if more rapid protection from serotypes unique to PPSV23 is desired.