Is asplenia considered to be an indication for a 3-dose HPV schedule?

No. The recommendation for a 3-dose HPV schedule does not apply to people with asplenia and neither does it apply to children 9 through 14 years with asthma, chronic granulomatous disease, chronic liver disease, chronic renal disease, central nervous system, anatomic barrier defects (such as a cochlear implant), complement deficiency, diabetes, heart disease or sickle cell disease unless the person is receiving immunosuppressive therapy for the condition.