Does live oral cholera vaccine (Vaxchora, Emergent Travel Health) need to be administered at an interval from other live oral or injectable vaccines?

According to CDC’s “General Best Practices for Immunization”, concerns about spacing between doses of live vaccines not given at the same visit applies only to live injectable or intranasal vaccines. Therefore, live oral cholera vaccine may be administered simultaneously or at any interval before or after administration of most other vaccines.

One exception is when Ty21a oral typhoid vaccine (Vivotif, Bavarian Nordic) and oral cholera vaccine are both indicated. ACIP recommends that oral cholera vaccine should be administered before Ty21a vaccine, and at least 8 hours should separate the cholera vaccine and the first dose of Ty21a to avoid the potential for interference between the oral cholera vaccine buffer solution and the enteric-coated Ty21a vaccine dose.