Home / Ask The Experts / Can we switch back and forth from separate vaccines at one visit to combination vaccines at another visit? For example, if a child is given separate DTaP, IPV, Hib, and HepB vaccines during her 2-month visit, could we give her either DTaP-IPV/Hib (Pentacel) or DTaP-HepB-IPV (Pediarix) at her 4-month visit?

Combination Vaccines
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Can we switch back and forth from separate vaccines at one visit to combination vaccines at another visit? For example, if a child is given separate DTaP, IPV, Hib, and HepB vaccines during her 2-month visit, could we give her either DTaP-IPV/Hib (Pentacel) or DTaP-HepB-IPV (Pediarix) at her 4-month visit?

Switching between combination and single-antigen vaccines poses no problem if you maintain the recommended minimum intervals for all vaccines and the vaccines are licensed for the age of the patient.

Last reviewed: July 15, 2023

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This page was updated on July 15, 2023.