Ask the Experts
Rabies
Who should be offered preexposure rabies vaccination?
Preexposure vaccination should be offered to persons in high-risk groups, such as veterinarians, animal handlers, and certain laboratory workers. Preexposure vaccination also should be considered for other persons whose activities bring them into frequent contact with rabies virus or potentially rabid bats, raccoons, skunks, cats, dogs, or other species at risk for having rabies. In addition, international travelers might be candidates for preexposure vaccination if they are likely to come in contact with animals in areas where dog rabies is enzootic and immediate access to appropriate medical care, including biologics, might be limited.
An ACIP statement on rabies was released in January 1999. What was new in the recommendations?
The most recent rabies ACIP statement ("Human Rabies Prevention–United States, 1999, Recommendations of the Advisory Committee on Immunization Practices") was published in MMWR on January 8, 1999. The 1999 statement contains information on a human rabies vaccine that was FDA-approved for use in the U.S. in 1997, recommendations regarding exposure to bats, recommendations regarding an observation period for domestic ferrets, and changes in how to administer rabies immune globulin.
If a bat is found in a room where a baby is sleeping, do you need to give postexposure prophylaxis?
Yes, rabies postexposure prophylaxis (PEP) is recommended. When a bat is found in a dwelling, even in the absence of a known bite or scratch, the recommendation calls for aggressive use of PEP. If possible, the bat should be safely collected and submitted for rabies diagnosis. Details of these recommendations were published in MMWR 1998; 47(01):1-5. The indications for PEP are fairly complex and depend on several factors. Providers who are responsible for decisions on PEP should also be familiar with the complete ACIP recommendations on human rabies prevention (MMWR 1999; 48(RR-1):1-21.
Reviewed on 5/07
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