- COVID-19
- Contraindications & Precautions
Can people who are immunocompromised or who have autoimmune disease be vaccinated with COVID-19 vaccines?
Yes, they may be vaccinated with any FDA-licensed or FDA-authorized COVID-19 vaccine (Moderna, Pfizer-BioNTech, or Novavax) as long as they do not have a contraindication to vaccination. Antibody testing is not recommended to assess for immunity to SARS-CoV-2 following COVID-19 vaccination.
Recipients should be counseled about the unknown and variable effectiveness of COVID-19 vaccination in immunocompromised populations and the potential for reduced immune responses. They may consider other practices to reduce their risk of infection. CDC has published additional information about respiratory virus prevention for people with weakened immune systems: www.cdc.gov/respiratory-viruses/risk-factors/weakened-immune-systems.html.
CDC provides detailed considerations for vaccination and the use of pemivibart (Pemgarda, Invyvid) long-acting monoclonal antibody for pre-exposure prophylaxis in people with moderate or severe immunocompromise here: www.cdc.gov/vaccines/covid-19/clinical-considerations/interim-considerations-us.html#immunocompromised.