Which HepB products can be given to adult patients?

Heplisav-B (Dynavax, 2-dose series), and Twinrix (GSK, combination HepA-HepB, 3-dose series) are approved for adults age 18 years and older. Engerix-B (GSK) and Recombivax HB (Merck), both administered as a 1.0 mL 3-dose series, are approved for adults age 20 years and older; young adults who are age 19 receive the 0.5 mL pediatric dose of Engerix-B and Recombivax HB. PreHevbrio (VBI, 3-dose series), was available and used in adults age 18 years and older between 2021 and 2024 before it was removed from the market following the bankruptcy of its manufacturer.