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  • Vaccine Recommendations

Where can I find information about the special vaccine needs of patients with immunodeficiencies caused by a by a medical condition or treatment, including stem cell transplants?

Due to the variety of causes and consequences of altered immunocompetence, and limited studies of vaccination with these conditions, vaccination recommendations for primary and secondary immunodeficiencies are generally based upon expert opinion.

CDC’s “General Best Practice Guidelines for Immunization” outline vaccine recommendations for people with various types of altered immunocompetence here: For a summary of specific vaccine recommendations for people with different types of primary and secondary immunodeficiencies, refer to Table 8-1 at that site. Additional information is available in the 2013 Infectious Diseases Society of America (IDSA) expert guideline on vaccination of the immunocompromised host, which informed CDC’s recommendations:

Last reviewed: August 22, 2020

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