Home / Ask The Experts / Several doses (antigen and diluent) of Shingrix recombinant zoster vaccine were mistakenly stored in our office freezer. One of these doses was administered to a patient. Is this dose valid and if not, when can it be repeated?

Administering Vaccines
Vaccine Administration Errors
Zoster (Shingles)
Administering Vaccines

Several doses (antigen and diluent) of Shingrix recombinant zoster vaccine were mistakenly stored in our office freezer. One of these doses was administered to a patient. Is this dose valid and if not, when can it be repeated?

Any Shingrix component, either antigen or diluent, that is exposed to freezing temperature should not be used. If a dose exposed to freezing temperature is given to a patient, the dose should be considered invalid and should be repeated 4 weeks after the invalid dose.

Last reviewed: August 25, 2025

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This page was updated on August 25, 2025.