Home / Ask The Experts / My medical assistant inadvertently administered a 0.5 mL dose of the RZV (Shingrix) diluent only. The dose did not contain any antigen. When can we administer a properly reconstituted dose?

Administering Vaccines
Vaccine Administration Errors

My medical assistant inadvertently administered a 0.5 mL dose of the RZV (Shingrix) diluent only. The dose did not contain any antigen. When can we administer a properly reconstituted dose?

The CDC zoster vaccine subject matter experts recommend that in this situation you should wait 4 weeks before giving a repeat dose because the diluent contains the ASO1 adjuvant and repeating the dose with a shorter interval could increase the side effects of the dose.

Last reviewed: February 27, 2025

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This page was updated on February 27, 2025.