How many doses of the 2025–2026 Formula COVID-19 adjuvanted protein subunit vaccine do recipients need this season?

The 2025–2026 formula Nuvaxovid (Sanofi-Novavax) vaccine is an option for any person age 12 years or older who is due for a 2025–2026 updated vaccination. Below are listed the 2025–26 season dosing schedules (if using Nuvaxovid for all doses) for different ages and health conditions:

• Age 12 through 64 years, not moderately or severely immunocompromised: one 2025–2026 formula dose, at least 8 weeks after most recent dose from a previous season
• Age 65 years and older, not moderately or severely immunocompromised: two 2025–2026 formula doses 6 months apart (minimum interval 2 months)
• Age 12 years or older, moderately or severely immunocompromised:
  • Previously unvaccinated: give 2 doses at least 3 weeks apart as an initial series, followed by a third dose about 6 months after dose 2 (minimum interval 2 months)
  • Previously completed an initial series of any COVID-19 vaccine (2 doses of Novavax protein subunit vaccine or 3 doses of an mRNA vaccine): give first 2025–2026 formula dose at least 8 weeks after most recent COVID-19 vaccine from the previous season, then give a second dose about 6 months later (minimum interval, 2 months)

See Immunize.org’s standing orders template for administration of 2025–2026 formula adjuvanted protein subunit vaccine to individuals age 12 years and older for details: www.immunize.org/wp-content/uploads/catg.d/p3141.pdf.