Is there any role for PCV13 in adults?

No. All adults age 50 years and older without a prior PCV vaccination are now routinely recommended to receive PCV20 or PCV21 alone or a 2-dose series of PCV15 followed by PPSV23 one year later. People in this age group with an immunocompromising condition, cochlear implant, or cerebrospinal fluid leak who are given PCV15 may receive PPSV23 as little as 8 weeks later. PCV13 is no longer recommended for adults; however, CDC states that in rare situations where no PCV15, PCV20, or PCV21 is available and a patient is otherwise unlikely to be vaccinated at all, an available dose of PCV13 may be used.