Is PPSV23 alone currently routinely recommended for any adults?

No. All adults for whom pneumococcal vaccination is recommended due to age (50 or older) or an underlying condition (age 19 through 49) are now recommended to receive a pneumococcal conjugate vaccine. When PCV20 or PCV21 is given, no further pneumococcal vaccination is recommended. If PCV15 is given to an adult, PPSV23 is recommended one year later (minimum interval of 8 weeks). Prior recipients of PPSV23 alone may now receive PCV15, PCV20, or PCV21 at least 1 year after the dose of PPSV23.