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  • Combination Vaccines
  • DTaP-IPV/Hib (Pentacel, Sanofi)
  • Hib (Haemophilus Influenzae Type B)
  • Scheduling & Administration

We inadvertently gave a child only the DTaP-IPV component of Pentacel (DTaP-IPV/Hib) not realizing that this component was intended to reconstitute the Hib component. Does this count as a valid dose of DTaP and IPV? Can we mix the unused Hib component with sterile water and give it separately?

Use of DTaP-IPV solution as the diluent for the Hib component is specifically written both on the Pentacel box AND on the DTaP-IPV vial label. The DTaP-IPV component will count as valid doses of DTaP and IPV vaccines, but take measures to prevent this error in the future. You cannot mix the Hib component with sterile water. ActHib must ONLY be reconstituted with either the DTaP-IPV solution supplied with Pentacel, or with a specific ActHib saline diluent. If you have a vial of lyophilized ActHib but neither diluent, you must contact the manufacturer (Sanofi) and obtain ActHib diluent.

Last reviewed: July 15, 2023

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