If a patient received Trumenba meningococcal B vaccine (MenB-FHbp) 2 months ago and Bexsero meningococcal B vaccine (MenB-4C) yesterday, should they complete the series with Trumenba or with Bexsero since the two brands are not interchangeable?

The patient can complete the series with either vaccine. If the patient lacks a high-risk condition for meningococcal B disease and is not at high risk of exposure due to an ongoing outbreak, then simply administer the final dose in the 2-dose series 6 months after the initial dose of the selected product. There needs to be a 6-month interval between two doses of the same brand to complete a MenB series for a person who is not at increased risk.

If the person is at increased risk for meningococcal B disease and needs a 3-dose MenB series, then decide which product (Bexsero or Trumenba) you will use to complete dose 2 and dose 3 of the series. The second dose of the selected brand may be given no sooner than 4 weeks after the previous dose of the same brand AND at least 4 weeks after the last dose of the other brand. Dose 3 should be given no sooner than 6 months after dose 1 of the same brand and 4 months after dose 2 of the same brand.