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  • Hepatitis B
  • For Children & Teens

I am confused about the volume of hepatitis B vaccine dose to give an adolescent. Is it 0.5 mL or 1.0 mL?

The dosage depends on the schedule and manufacturer of the vaccine that you are using. For children 11 through 15 years of age, the 2-dose Recombivax HB volume is 1.0 mL. Otherwise, the 3-dose schedule of Recombivax HB or Engerix B is 0.5 mL through age 19 years. Heplisav-B, the 2-dose HepB vaccine given with a 4-week interval between 0.5 mL doses, is licensed for adolescents and adults beginning at age 18 years. offers a handy resource with charts detailing the correct dosages and schedules for monovalent HepB and HepA vaccines and combination products that include HepA and HepB vaccines. Go to

Last reviewed: July 21, 2023

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