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  • Administering Vaccines
  • General Issues

Is it okay to draw up vaccines at the beginning of the shift? If it isn’t, how much in advance can this be done?

The ACIP discourages the practice of prefilling vaccine into syringes, primarily because of the increased possibility of administration and dosing errors. An exception may be considered when only a single type of vaccine is to be administered during a clinic (e.g., influenza). Another reason to discourage the practice in general is that some vaccines have a very limited shelf life after reconstitution. If the reconstituted vaccine is not used within the designated time period, it must be discarded. A chart of the time allowed between reconstitution and use, “Vaccines with Diluents: How to Use Them,” is available at For more information on prefilling syringes, please read

Last reviewed: December 28, 2022

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