• Dengue
  • Scheduling & Administration

If Dengvaxia is given intramuscularly instead of subcutaneously, should the dose be repeated?

No, the dose should not be repeated. The Clinical Implications of Nonstandard Vaccination Practices subsection of the Vaccine Administration section of CDC’s General Best Practices for Immunization explains that the immune response to vaccines recommended to be administered by the subcutaneous route is unlikely to be affected if the vaccines are inadvertently administered by the intramuscular route. For this reason, repeating doses of vaccine administered by the intramuscular route when recommended by the subcutaneous route is not necessary. See this subsection here: www.cdc.gov/vaccines/hcp/imz-best-practices/vaccine-administration.html#cdc_report_pub_study_section_6-clinical-implications-of-nonstandard-vaccination-practices.

Last reviewed: January 17, 2025

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