Are COVID-19 vaccines safe during pregnancy?

Yes. Evidence continues to demonstrate that COVID-19 vaccination is safe and effective during any stage of pregnancy; the benefits of vaccination clearly outweigh any known or potential risks of COVID-19 vaccination during pregnancy. The currently licensed COVID-19 vaccines are nonreplicating vaccines and cannot cause infection in either the mother or the fetus. No evidence exists of risk to the fetus from vaccinating during pregnancy with nonreplicating vaccines in general.

Data from the Vaccine Adverse Events Reporting System (VAERS), the V-safe surveillance system, and the V-safe pregnancy registry have not signaled any safety concerns related to vaccination during pregnancy for mother or infant.

Pregnant women have historically been at an increased risk of severe disease, adverse pregnancy outcomes, and maternal death from COVID-19 infections.

The American College of Obstetricians and Gynecologists (ACOG) recommends all pregnant women receive any age-appropriate 2026–2027 COVID-19 vaccine if they are due for vaccination; ACOG recommends vaccination in any trimester as soon as possible to protect maternal and infant health. Current ACOG recommendations are available here: www.acog.org/clinical/clinical-guidance/practice-advisory/articles/2020/12/covid-19-vaccination-considerations-for-obstetric-gynecologic-care. ACOG’s 2026 maternal schedule is available at www.acog.org/clinical-information/maternal-immunization-schedule.