Ask the Experts: All Questions

Ask the Experts is one of our most popular destinations for healthcare professionals. Our experts provide clear, easy-to-understand answers to commonly asked questions about vaccines and their use.

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The production of a few vaccines, including those for varicella, rubella, hepatitis A, and one of the COVID-19 vaccines (Janssen, Johnson & Johnson) involves growing the viruses in human cell culture. Two human cell lines provide the cell cultures needed for producing vaccines; these lines were developed from two legally aborted fetuses in the 1960s. These cell lines are maintained to have an indefinite life span. No fetal tissue has been added since the cell lines were originally created.

Some parents are concerned about this issue because of misinformation they have encountered on the Internet. Two such untrue statements are that ongoing abortions are needed to manufacture vaccines and vaccines are contaminated with fetal tissue.

Parents can read the facts and several thought-provoking articles about this issue at www.immunize.org/talking-about-vaccines/religious-concerns.asp and then make an informed decision.

A Catholic Pontifical Academy for Life statement that Catholic parents have no general obligation to refuse permission for these vaccines is summarized at www.immunize.org/talking-about-vaccines/vaticandocument.htm.

Last reviewed: August 31, 2022

ACIP recommends that people working in healthcare settings be vaccinated against COVID-19, influenza, hepatitis B, measles, mumps, rubella, varicella, and pertussis. Adults are generally assumed to have been vaccinated against polio in childhood; any adult known or strongly suspected of being unvaccinated against polio should be vaccinated. For measles, mumps, rubella, and varicella, serologic evidence of immunity is an acceptable substitute for documentation of vaccination. In addition, microbiologists working in a laboratory should receive vaccination against meningococcal ACWY and meningococcal serogroup B disease. In rare cases, some laboratory personnel should also receive a single polio vaccine booster and typhoid vaccines. For more information, refer to the current CDC recommended adult immunization schedule or the 2011 ACIP recommendations for immunization of healthcare personnel, www.cdc.gov/mmwr/pdf/rr/rr6007.pdf.

Last reviewed: January 27, 2025

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