has been refreshed! Take a tour.
Issue 1161: January 6, 2015

Ask the Experts–Question of the Week: Do any of the bacterial vaccines that are recommended for people with…read more

FDA approves Rapivab to treat influenza infection

On December 19, FDA approved Rapivab (peramivir) to treat influenza infection in adults.

Rapivab is an inhibitor of influenza virus neuraminidase, an enzyme that releases viral particles from infected cells. Neuraminidase inhibitors are commonly used to treat influenza infection. Rapivab is the first neuraminidase inhibitor approved for intravenous (IV) administration and is administered as a single IV dose. It is intended for patients age 18 years and older who have acute uncomplicated influenza and have shown symptoms of influenza for no more than two days.

Rapivab and other antiviral drugs used to treat influenza are not substitutes for vaccination. CDC recommends all people age 6 months and older receive an annual influenza vaccine.

Rapivab is manufactured by BioCryst Pharmaceuticals, based in Durham, North Carolina.

Related Link Back to top

IAC Spotlight! Six more healthcare organizations join IAC's Influenza Vaccination Honor Roll for mandatory healthcare worker vaccination

IAC urges qualifying healthcare organizations to apply for its Influenza Vaccination Honor Roll. The honor roll recognizes hospitals, medical practices, professional organizations, health departments, and government entities that have taken a stand for patient safety by implementing mandatory influenza vaccination policies for healthcare personnel. More than 450 organizations are now enrolled.

Since December 7, when IAC Express last reported on the Influenza Vaccination Honor Roll, six healthcare organizations have been enrolled.

Newly added healthcare organizations, hospitals, and government agencies
  • Carolinas HealthCare System, Charlotte, NC
  • Detroit Receiving Hospital and University Health, Detroit, MI
  • Naval Medical Center Portsmouth, Portsmouth, VA
  • Ottawa County Department of Public Health, Holland, MI
  • St. Vincent's HealthCare, Jacksonville, FL
  • UF Health Shands Hospital, Gainesville, FL
Related Links Back to top

January is Cervical Cancer Awareness Month

January is Cervical Health Awareness Month, and the National Cervical Cancer Coalition (NCCC) urges every woman to make a New Year’s resolution to talk to her healthcare provider about preventing cervical cancer. The NCCC website includes resources and ideas to help healthcare and social services professionals get the word out about preventing cervical cancer, including promoting vaccination against HPV infection. Related Links

From AAFP, AAP, ACOG, ACP, CDC, and IAC HPV Resources from IAC HPV Resources from CDC HPV Resources from the Vaccine Education Center
HPV Resources from AAP
HPV resources from ACOG
HPV Resources from Voices for Vaccines
Back to top

National Public Health Information Coalition offers searchable databases of influenza resources

The National Public Health Information Coalition (NPHIC) offers many resources to help healthcare professionals communicate about influenza. Materials posted in the pandemic and seasonal flu communications resource libraries were created by colleagues at public health agencies across the country. Save time and money by searching the library databases to find available resources you can use. The libraries include materials on prevention, vaccination, and advice for pregnant women, parents, and other targeted audiences. You will find news releases, brochures, fact sheets, radio and TV PSAs, and websites. The National Public Health Information Coalition is the premier network of public health communicators in the United States and U.S. territories.

Back to top

Influenza is serious; many resources are available to help healthcare professionals provide vaccination

Vaccination remains the single most effective means of preventing influenza, and is recommended for everyone age six months and older. If you don't provide influenza vaccination in your clinic, please recommend vaccination to your patients and refer them to a clinic or pharmacy that provides vaccines or to the HealthMap Vaccine Finder to locate sites near their workplaces or homes that offer influenza vaccination services.

Following is a list of resources related to influenza disease and vaccination for healthcare professionals and the public: Back to top

CDC publishes figure displaying death rates from viral hepatitis among adults in the U.S., 1999–2011

CDC published QuickStats: Death Rates from Viral Hepatitis Among Adults Aged ≥18 Years, by Age Group and Sex—National Vital Statistics System, United States, 1999–2011 in the January 2 issue of MMWR (page 1230). The first paragraph is reprinted below.

From 1999 to 2011, the death rate for viral hepatitis as the underlying or contributing cause of death among those aged 45–64 years increased 2.2 times among men (from 11.9 to 26.5 per 100,000 population) and 2.3 times among women (from 3.7 to 8.4 per 100,000 population). The death rate decreased 60% among men aged 18–44 years; among women aged 18–44 years the death rate did not change from 1999 to 2002 and then decreased 46% from 2003 to 2011. For men aged ≥65 years the death rate did not change from 1999 to 2003 and then increased 40% from 2004 to 2011. For women aged ≥65 years the rate did not change from 1999 to 2011.

Related Links Back to top

December issue of CDC's Immunization Works newsletter now available

CDC recently released the December issue of its monthly newsletter, Immunization Works, and posted it on the website of the National Center for Immunization and Respiratory Diseases (NCIRD). The newsletter offers the immunization community information about current topics. The information is in the public domain and can be reproduced and circulated widely.

Related Links Back to top

Question of the Week

Do any of the bacterial vaccines that are recommended for people with functional or anatomic asplenia need to be given before splenectomy? Do the doses count if they are given during the 2 weeks prior to surgery?  

Answer: Pneumococcal conjugate vaccine (PCV13), Haemophilus influenzae type b vaccine (Hib), and meningococcal conjugate vaccine (MCV4) should be given 14 days before splenectomy, if possible. Doses given during the 2 weeks (14 days) before surgery can be counted as valid. If the doses cannot be given prior to the splenectomy, they should be given as soon as the patient’s condition has stabilized after surgery. Pneumococcal polysaccharide vaccine (PPSV23) should be administered 8 weeks after the dose of PCV13 for people 2 years of age and older. 

About IAC's Question of the Week

Each week, IAC Express highlights a new, topical, or important-to-reiterate Q&A. This feature is a cooperative venture between IAC and CDC. William L. Atkinson, MD, MPH, IAC's associate director for immunization education, chooses a new Q&A to feature every week from a set of Q&As prepared by experts at CDC’s National Center for Immunization and Respiratory Diseases.

We hope you enjoy this new feature and find it helpful when dealing with difficult real-life scenarios in your vaccination practice. Please encourage your healthcare professional colleagues to sign up to receive IAC Express at

If you have a question for the CDC immunization experts, you can email them directly at There is no charge for this service.

Related Links Back to top

About IZ Express

IZ Express is supported in part by Grant No. 1NH23IP922654 from CDC’s National Center for Immunization and Respiratory Diseases. Its contents are solely the responsibility of and do not necessarily represent the official views of CDC.

IZ Express Disclaimer
ISSN 2771-8085

Editorial Information

  • Editor-in-Chief
    Kelly L. Moore, MD, MPH
  • Managing Editor
    John D. Grabenstein, RPh, PhD
  • Associate Editor
    Sharon G. Humiston, MD, MPH
  • Writer/Publication Coordinator
    Taryn Chapman, MS
    Courtnay Londo, MA
  • Style and Copy Editor
    Marian Deegan, JD
  • Web Edition Managers
    Arkady Shakhnovich
    Jermaine Royes
  • Contributing Writer
    Laurel H. Wood, MPA
  • Technical Reviewer
    Kayla Ohlde

This page was updated on .