|CDC Publishes Recommendations that Newborns Receive Hepatitis B Vaccine within 24 Hours of Birth — AAFP, AAP and ACOG Concur
|Published July/August 2018
|On January 12, 2018, CDC published “Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP) in MMWR Recommendations and Reports,” (Vol.67, No.1). This 36-page document contains full recommendations for the use of hepatitis B vaccine in infants, children, teens and adults, as well as guidance on many other related topics.
What has changed for newborns?
The most significant change in these published recommendations is that medically stable newborns who weigh at least 2,000 gm and whose mothers’ hepatitis B surface antigen (HBsAg) test is documented to be negative, should receive hepatitis B vaccine within 24 hours of birth. Prior to this (since 2005), the recommendation was to administer the birth dose of hepatitis B vaccine at any time prior to hospital discharge. There was also language permitting a delay in administering the birth dose until after hospital discharge, but this was only during rare circumstances and on a case-by-case basis when certain specific criteria were met. However, this option is no longer included in the hepatitis B recommendations for newborns.
AAFP, AAP and ACOG agree
The American Academy of Family Physicians (AAFP), American Academy of Pediatrics (AAP), and American College of Obstetricians and Gynecologists (ACOG) are all in agreement with the recommendation to vaccinate newborns within 24 hours of birth. AAP included this in its recently published Red Book 2018–2021: Report of the Committee on Infectious Diseases (page 421, Table 3.24).
Administering the hepatitis B birth dose within 24 hours of birth was first published in 2017 in the Recommended Immunization Schedule for Children and Adolescents Aged 18 Years or Younger, United States, 2017, which was endorsed by AAFP, AAP and ACOG. It appears in the 2018 immunization schedule for children and adolescents as well.
The exact language regarding universal hepatitis B vaccination of infants in the ACIP recommendations on pages 16–17 is reprinted below:
Universal Vaccination of Infants
To access CDC guidance on hepatitis B-related topics such as the management of low birth weight infants, infants whose mothers are HBsAg positive or whose HBsAg status is unknown, and the management of HBsAg-positive mothers, consult the ACIP recommendations for hepatitis B.
From the Immunization Action Coalition
Vaccine Education Center at the Children’s Hospital of Philadelphia
Centers for Disease Control and Prevention