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Monkeypox
Vaccines: Monkeypox
This page provides links to key monkeypox vaccine resources from Immunize.org, CDC, and other partners.
Information about monkeypox disease, treatment, and outbreak response is available from CDC's Monkeypox main page.
Jynneos (Bavarian Nordic) is the primary vaccine used to prevent monkeypox. Information about ACAM2000 (Smallpox (Vaccinia) Vaccine, Live), is also included.
For the most current monkeypox vaccine information, subscribe to Immunize.org's weekly e-newsletter, IZ Express.
CDC Monkeypox
Main page for all CDC monkeypox disease and vaccination information
Orthopoxviruses (Smallpox and Monkeypox)
ACIP Vaccine Recommendations
These headings link you to the corresponding sections below
Information about Monkeypox Vaccine Products
Vaccine Information Statements (VIS) and Fact Sheets
Clinic Resources and Tools
Vaccine administration (Subcut and ID)
Clinical considerations for use of monkeypox vaccines
Vaccine storage and handling
Patient Education Materials
Frequently Asked Questions
Key Contacts for Monkeypox Vaccine Information and Policies
Information about Monkeypox Vaccine Products
General
Vaccines (CDC)
Jynneos
Jynneos package insert (FDA) [pdf]
ACAM2000
ACAM2000 package insert (FDA) [pdf]
Vaccine Information Statements (VIS) and Fact Sheets
Jynneos
VIS: Smallpox/Monkeypox Vaccine (JYNNEOS): What You Need to Know (CDC) [pdf]  |  Spanish [pdf]
Jynneos Vaccine: EUA Fact Sheet for Healthcare Providers Administering Vaccine (FDA) [pdf]
Jynneos Vaccine: EUA Fact Sheet for Recipients and Caregivers (FDA) [pdf]
ACAM2000
Medication Guide: Smallpox (Vaccinia) Vaccine, Live – ACAM2000 (Emergent BioSolutions [FDA-approved]) [pdf]
Clinic Resources and Tools
Vaccine administration (Subcut and ID)
Jynneos
Jynneos subcutaneous vaccine administration
Subcutaneous Vaccine Preparation and Administration Summary (standard regimen) - for Adults with Certain Medical Conditions and Children: Jynneos Smallpox and Monkeypox Vaccine (CDC) [pdf]
Standing Orders for Administering Vaccine Subcutaneously (standard regimen) - for Adults with Certain Medical Conditions and Children: Jynneos Smallpox and Monkeypox Vaccine (CDC) [pdf]
Video: Subcutaneous (SC or Subcut) Injection: Administration
Jynneos intradermal vaccine administration
Intradermal Vaccine Preparation and Administration Summary (alternative dosing regimen) - for Adults in the General Population: JYNNEOS Smallpox and Monkeypox Vaccine (CDC) [pdf]
Standing Orders for Administering Vaccine Intradermally (aternative dosing regimen) - for Adults in the General Population: JYNNEOS Smallpox and Monkeypox Vaccine (CDC) [pdf]
Video: How to administer a Jynneos vaccine intradermally (CDC)
Jynneos vaccine administration: general information
Interchangeability of dosing regimens (CDC)
Coadministration of Jynneos vaccine with other vaccines (CDC)
Safety (contraindications and precautions) (CDC)
Vaccine administration errors and deviations (CDC)
ACAM2000
Vaccine Administration: Step-by-Step Instructions (CDC)
Clinical considerations for use of monkeypox vaccines
Interim Clinical Considerations for Use of JYNNEOS and ACAM2000 Vaccines during the 2022 U.S. Monkeypox Outbreak (CDC)
Interim guidance (for Jynneos vaccine) (CDC)
JYNNEOS vaccine (CDC)
ACAM2000 vaccine (CDC)
Vaccination strategies (CDC)
Includes post-exposure prophylaxis (PEP) and pre-exposure prophylaxis (PrEP)
Health equity considerations (CDC)
Monkeypox and Smallpox Vaccine Guidance (CDC)
Interim Guidance for Prevention and Treatment of Monkeypox in Persons with HIV Infection – United States, August 2022 (CDC)
Clinical considerations for monkeypox in people who are pregnant or breastfeeding (vaccine section) (CDC)
Vaccine storage and handling
Jynneos
Storage and Handling Summary: JYNNEOS Smallpox and Monkeypox Vaccine (CDC) [pdf]
Healthcare provider letter on acceptable vaccine storage temperatures (update to package insert) (Bavarian Nordic) [pdf]
SNS Products: Vaccines and Treatment Available for Use in Monkeypox Response (ASPR)
Includes table of lot numbers and expiration dates for SNS-held Jynneos vaccine
ACAM2000
Refer to ACAM2000 package insert for complete storage and handling information
ACAM2000 Package Insert (FDA) [pdf]
Patient Education
Monkeypox Fast Facts: JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) (FDA) [pdf]
Frequently Asked Questions
Monkeypox Vaccination FAQs (CDC)
Monkeypox Clinician FAQs: Vaccines and Treatment (CDC)
Key Contacts for Monkeypox Vaccine Information and Policies
State/local/territorial Immunization Program Directory (AIM)
Jynneos (Bavarian Nordic)
Main website: www.bavarian-nordic.com
Medical information: 1-844-422-8274 or
medical.information_us@bavarian-nordic.com
ACAM2000 (Emergent BioSolutions)
Main website: www.emergentbiosolutions.com
Medical information: 1-877-246-8472 or
medicalinformation@ebsi.com
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CDC Monkeypox Vaccination
Subscribe to IZ Express
Centers for Disease Control and Prevention (CDC)
Monkeypox [main page]
Administration for Strategic Preparedness & Response (ASPR)
JYNNEOS Monkeypox Vaccine Distribution by Jurisdiction
Food & Drug Administration (FDA)
JYNNEOS
ACAM2000 (Smallpox Vaccine) Questions and Answers
World Health Organization (WHO)
Monkeypox [main page]
Infectious Diseases Society of America (IDSA)
Monkeypox: What You Need to Know
American Medical Association (AMA)
Orthopoxvirus and monkeypox coding and guidance
This page was updated on August 12, 2022.
This page was reviewed on August 12, 2022.
 
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