IZ Express

Issue 1752: April 17, 2024

Top Stories
Immunize.org Website and Clinical Resources
Featured Resources
Notable Publications
Global News
Upcoming Events

Top Stories

Immunize.org updates pneumococcal Ask the Experts clinical questions and answers

Immunize.org’s team of experts reviewed and updated all questions and answers in Ask the Experts: Pneumococcal.

Updates reflect the latest recommendations for pneumococcal vaccination of children. This includes the use of 20-valent pneumococcal conjugate vaccine (PCV20) in children, as well as changes to recommendations for 23-valent pneumococcal polysaccharide vaccine (PPSV23) and PCV15 in high-risk children in light of the option to administer a single dose of PCV20. Answers regarding children and adults were also updated with links to relevant CDC resources to support pneumococcal vaccination, including the CDC PneumoRecs VaxAdvisor mobile app, as well as links to Immunize.org resources, including standing orders templates for pneumococcal vaccination of adults and children.

Immunize.org’s Ask the Experts main page leads you to 30 web pages on various topics with more than 1,300 common or challenging questions and answers about vaccines and their administration. Immunize.org’s team of experts includes Kelly L. Moore, MD, MPH (team lead); Carolyn B. Bridges, MD, FACP; Iyabode Beysolow, MD, MPH; and Jane Zucker, MD, MPH.

Related Links

Immunize.org updates meningococcal Ask the Experts clinical questions and answers

Immunize.org updated all clinical questions and answers related to meningococcal ACWY and meningococcal B vaccines.

References to the use of Menactra-brand MenACWY vaccines were removed (except regarding historical doses) now that all remaining doses of this product have expired. The questions and answers also address ACIP recommendations for pentavalent MenABCWY combination vaccine, Penbraya (Pfizer) as an option for children and adults age 10 years or older when both MenACWY and MenB (Trumenba) vaccines are needed at the same visit, as long as there is a 6-month interval between Penbraya doses.

Immunize.org’s Ask the Experts main page leads you to 30 web pages on various topics with more than 1,300 common or challenging questions and answers about vaccines and their administration. Immunize.org’s team of experts includes Kelly L. Moore, MD, MPH (team lead); Carolyn B. Bridges, MD, FACP; Iyabode Beysolow, MD, MPH; and Jane Zucker, MD, MPH.

Related Links

Immunize.org updates its Questions and Answers series of patient handouts on pertussis, tetanus, and diphtheria

Immunize.org recently updated three topics in its series of educational resources suitable for patients or healthcare providers:

Changes include updates to disease epidemiology, removal of references to the pediatric DT vaccine that is no longer available, and CDC’s new recommendations for off-label use of adult Td instead of DTaP in children younger than age 7 years who develop encephalopathy not due to another identifiable cause within 7 days of a dose of DTaP. Because this condition could be an adverse reaction to the pertussis component of DTaP, these new recommendations for Td replace previous recommendations to use DT to ensure tetanus and diphtheria protection in such children.


Related Links

National Infant Immunization Week is April 22–29; prepare your promotion with CDC’s digital media toolkit

National Infant Immunization Week (NIIW), April 22–29, highlights the importance of protecting infants from vaccine-preventable diseases. Since 1994, hundreds of communities have celebrated the crucial role vaccination plays in protecting our children, communities, and public health.

CDC and the American Academy of Pediatrics (AAP) recommend that children stay on track with their well-child appointments and routine vaccinations. Completing the recommended childhood immunizations by age 2 years is the best way to protect young children from 16 potentially life-threatening diseases.

CDC makes it simple to plan your NIIW activities by using their promotional materials including English and Spanish logos, sample social media content, social graphics, and key messages. Please share your posts using the hashtag #ivax2protect.

AAP resources will be released on April 18 at aap.org.

Related Links

Nominate a champion! Association of Immunization Managers accepting nominations for Immunization Champions to represent states, territories, and some cities, due May 10.

Today, you can recognize an immunization champion you know! The Association of Immunization Managers (AIM) invites nominations for its Immunization Champion Awards. The awards honor those doing an exemplary job to promote immunizations for children and adults in their communities. The program will honor a champion from each of the 50 U.S. states, the District of Columbia, six major cities, and eight U.S. territories. Each jurisdiction directly funded by CDC for immunization work will be represented.

Visit the AIM website to learn more about the Immunization Champion Awards. Email questions to champions@immunizationmanagers.org.

Related Links

Our final weekly influenza update of the season: influenza-like illness activity remains elevated but waning

For week 14, ending April 6, CDC’s Weekly U.S. Influenza Surveillance Report, FluView shows that seven jurisdictions experienced moderate activity and one state experienced high activity. Nationwide, 2.8% of patient visits reported through the Outpatient Influenza-Like Illness Surveillance Network (ILINet) were due to respiratory illness that included fever plus a cough or sore throat (i.e., ILI). The national baseline is 2.9%. Five pediatric influenza-associated deaths were reported this week, bringing the total to 138 children who died of influenza thus far during the 2023–24 season.

Visit the CDC Respiratory Virus Hospitalization Surveillance Network (RESP-NET) for weekly reports of hospitalizations across the United States due to three vaccine-preventable seasonal respiratory viruses: COVID-19, influenza, and RSV.

Influenza Vaccination
CDC recommends everyone age 6 months and older get annual influenza vaccination.

This story represents the final routine story on influenza-like-illness activity for the 2023–24 season. Late-season influenza vaccination may be helpful, especially for young infants just turning 6 months of age, as long as influenza is circulating.

Don't forget that some children need a second dose in their first season of influenza vaccinations.

Locate influenza and COVID-19 vaccines in your area by entering your zip code in the VaccineFinder on Vaccines.gov or Vacunas.gov. To be listed as a provider by VaccineFinder, see the information on this website.

Related Links

Help parents understand why HPV vaccine is recommended for preteens. Watch the 1-minute answer, part of the Ask the Experts Video Series on YouTube.

This week, our featured episode from the Ask the Experts Video Series is Some parents resist HPV vaccination of their 11- and 12-year-olds because they are not sexually active. How should I counter this position? The video briefly describes how to talk to parents about the importance of starting and completing HPV vaccination prior to exposure to the virus.

The 1-minute video is available on our YouTube channel, along with our full collection of quick video answers to popular Ask the Experts questions.

Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise:

Vaccines in the news

These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.

Immunize.org Website and Clinical Resources

Spotlight on the website: National Infant Immunization Week

This week’s Spotlight on the Website highlights Immunize.org content that can aid you with delivering infant immunizations.

Our Clinical Resources A–Z section contains 41 print-ready resources regarding infant immunization for providers and recipients. Several patient handouts are also available in multiple languages. Topics include answers to questions patients frequently ask about vaccines, how to respond to vaccine-hesitant parents, and strategies for addressing vaccine anxiety in infants and toddlers. The list of these resources can be found here.

Our popular Ask the Experts web section includes many clinical questions and answers specific to vaccination of infants. Infant-specific content is available within general topics, such as scheduling and administering vaccines, as well as questions and answers about specific vaccines infants receive. By filtering or using a keyword search for infant immunization, you can find Ask the Experts answers specific to infants.

Featured Resources

Before we run out! Place your order for these sturdy, laminated versions of the 2024 U.S. immunization schedules from Immunize.org.

Laminated versions of the 2024 U.S. child and adolescent immunization schedule and the 2024 U.S. adult immunization schedule are shipping. We anticipate selling out, so put in your order now!

While the schedules are available online from CDC at no cost, Immunize.org’s printed, laminated booklets are ideal for use in any busy healthcare setting where vaccinations are given.

  • Durable: their tough coating can be wiped down, and they’re durable enough to stand up to a year's worth of use
  • Format: each schedule is produced in a 16-page, 8.5” X 11” booklet format; with color coding for easy reading, our laminated schedules replicate the original CDC formatting, including all tables and notes
  • Easy access to CDC updates: CDC added an online addendum page to the schedule, where new recommendations from ACIP made during 2024 can be posted. The laminated schedule addendum pages include custom QR codes you can scan to view or print the current CDC addendum from CDC's website, as needed.
  • Adult schedule bonus content: the adult schedule includes a bonus page with Immunize.org’s popular 1-page handout summarizing the dose, route, and needle size recommendations for all vaccines and recipients


1 copy: $10.00
2–4 copies: $9.50 each
5–19 copies: $8.50 each
20–99 copies: $7.50 each
100–499 copies: $6.00 each
500–999 copies: $5.00 each
1,000–1,999 copies: $4.00 each
2,000+ copies: $3.25 each

Visit the Shop Immunize.org: Laminated Schedules web page to view images of all the pages, to download the order form, and to order today!

For additional information, call 651-647-9009 or email admininfo@immunize.org.

Related Links

Recap: CDC releases simple, parent-friendly 2024 immunization schedules in English and Spanish

CDC now offers simple, parent-friendly, and downloadable versions of the childhood immunization schedules:


Related Links
Notable Publications

"Measles—United States, January 1, 2020–March 28, 2024" published in MMWR

CDC published Measles—United States, January 1, 2020–March 28, 2024 on April 11 in MMWR. A portion of the summary appears below.

Although endemic U.S. measles was declared eliminated in 2000, measles importations continue to occur. Prolonged outbreaks during 2019 threatened the U.S. measles elimination status. . . .

During January 1, 2020–March 28, 2024, a total of 338 U.S. measles cases were reported; 29% of these cases occurred during the first quarter of 2024, almost all in persons who were unvaccinated or whose vaccination status was unknown. As of the end of 2023, U.S. measles elimination status was maintained. . . .

Risk for widespread U.S. measles transmission remains low because of high population immunity. Enhanced efforts are needed to increase routine U.S. vaccination coverage, encourage vaccination before international travel, identify communities at risk for measles transmission, and rapidly investigate suspected measles cases to reduce cases and complications of measles.

Access the MMWR article in HTML or PDF.

Related Link

  • CDC: MMWR main page providing access to the MMWR family of publications

"Assessment of Risk for Sudden Cardiac Death among Adolescents and Young Adults after Receipt of COVID-19 Vaccine—Oregon, June 2021–December 2022" published in MMWR

CDC published Assessment of Risk for Sudden Cardiac Death among Adolescents and Young Adults after Receipt of COVID-19 Vaccine—Oregon, June 2021–December 2022 on April 11 in MMWR. For context, 979,289 doses of COVID-19 vaccines were administered to Oregonians aged 16–30 years from May 1, 2021 through December 31, 2022. A portion of the abstract appears below.

In April 2021, cases of myocarditis after COVID-19 vaccination, particularly among young male vaccine recipients, were reported to the Vaccine Adverse Event Reporting System. To assess this possibility, investigators searched death certificates for Oregon residents aged 16–30 years who died during June 2021–December 2022 for cardiac or undetermined causes of death. For identified decedents, records in Oregon’s immunization information system were reviewed for documentation of mRNA COVID-19 vaccination received ≤100 days before death. Among 1,292 identified deaths, COVID-19 was cited as the cause for 30. For 101 others, a cardiac cause of death could not be excluded; among these decedents, immunization information system records were available for 88, three of whom had received an mRNA COVID-19 vaccination within 100 days of death. Of 40 deaths that occurred among persons who had received an mRNA COVID-19 vaccine dose, three occurred ≤100 days after vaccination. Two of these deaths were attributed to chronic underlying conditions; the cause was undetermined for one. No death certificate attributed death to vaccination. These data do not support an association between receipt of mRNA COVID-19 vaccine and sudden cardiac death among previously healthy young persons [emphasis added]. COVID-19 vaccination is recommended for all persons aged ≥6 months to prevent COVID-19 and complications, including death.

Access the MMWR article in HTML or PDF.

Related Link

  • CDC: MMWR main page providing access to the MMWR family of publications

Global News

World Immunization Week is the last week of April; this year's theme is "Humanly Possible: Saving Lives Through Immunization"

World Vaccination Week (WIW) is traditionally celebrated the last week of April. A portion of WHO's press release about WIW appears below.

This year's campaign aims to:

  • Celebrate 50 years of children growing up protected against vaccine-preventable diseases.
  • Promote demand for immunization and conduct catch-up vaccination, wherever applicable, to reach zero-dose and under-immunized children in the Western Pacific.
  • Increase recognition and awareness of the value of vaccines across the life-course, and mitigate risk of vaccine-preventable disease outbreaks.

Related Links
"COVID-19 Vaccination Coverage—World Health Organization African Region, 2021–2023" published in MMWR

CDC published COVID-19 Vaccination Coverage—World Health Organization African Region, 2021–2023 on April 11 in MMWR. A portion of the summary appears below.

The World Health Organization African Region did not receive enough COVID-19 vaccine doses to vaccinate everyone for whom vaccination was recommended and lagged behind other regions. . . .

During 2021–2023, the cumulative number of COVID-19 vaccine doses received in the African Region increased from 321 million to 860 million, and 646 million doses were administered. Cumulative total population coverage with ≥1 dose ranged by country from 0.3% to 89%. By the end of 2023, coverage with a primary COVID-19 vaccination series increased from 7% to 32% for the total population, and increased to 52% among older age groups and to 48% among health care workers in a subset of countries in the African Region. . . .

Additional outreach is needed to increase COVID-19 vaccination coverage among priority high-risk populations. Integrating COVID-19 vaccination into routine immunization and primary health care services could strengthen adult vaccination platforms and improve pandemic preparedness.

Access the MMWR article in HTML or PDF.

Related Link

  • CDC: MMWR main page providing access to the MMWR family of publications

Upcoming Events

In-person: Registration open for “National Immunization Conference 2024” on August 12–14 in Atlanta; abstract deadline extended to April 26; CE credit offered

CDC will host its National Immunization Conference 2024 (NIC) on August 12–14 in Atlanta, GA. Program content will cover science, policy, education, and implementation issues related to immunization and vaccine-preventable diseases.

The abstract deadline was extended to April 26. Notification of acceptance will be sent in mid-June. View abstract submission guidelines.

Registration is now open. The general attendee fee is $685. CE will be offered. Register for the conference.

See CDC's National Immunization Conference 2024 website for more information.

For more upcoming events, visit our Calendar of Events.

About IZ Express

IZ Express is supported in part by Grant No. 1NH23IP922654 from CDC’s National Center for Immunization and Respiratory Diseases. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.

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ISSN 2771-8085

Editorial Information

  • Editor-in-Chief
    Kelly L. Moore, MD, MPH
  • Managing Editor
    John D. Grabenstein, RPh, PhD
  • Associate Editor
    Sharon G. Humiston, MD, MPH
  • Writer/Publication Coordinator
    Taryn Chapman, MS
    Courtnay Londo, MA
  • Style and Copy Editor
    Marian Deegan, JD
  • Web Edition Managers
    Arkady Shakhnovich
    Jermaine Royes
  • Contributing Writer
    Laurel H. Wood, MPA
  • Technical Reviewer
    Kayla Ohlde

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