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Issue 1,652: September 14, 2022
Top Stories Pages and Handouts
Vaccine Information Statements
Featured Resources
Notable Publications
Global News
Upcoming Events
Top Stories

Time for a reset! Updated COVID-19 vaccination resources from and CDC to prepare for this fall’s bivalent booster dose program.

The September 1, 2022, recommendation for bivalent COVID-19 booster doses for all people age 12 years and older who have completed a primary series, regardless of previous booster doses, represents a major reset in the U.S. COVID-19 vaccination program. Every practice involved in administering or recommending COVID-19 vaccination needs to review and update its practices and patient materials now. CDC and FDA have issued important updated fact sheets, immunization schedules, clinical considerations, and vaccine administration resources. helps you access all of this new information easily. Here are resources and links you need to have at hand:

You will see in our materials that bivalent mRNA vaccine resources have been added and links to most resources for the original monovalent Pfizer-BioNTech “purple cap” formulation have been removed. All remaining doses of this purple cap formulation expire at the end of this month. As guidelines for COVID-19 vaccines are updated and new CDC materials are released, the page will continue to be updated.

Related Links

Happy Mexican Independence Day, September 16! Here’s an orientation to vaccination information and advocacy in Mexico.

¡Viva México! September 16 is the 212th anniversary of Mexico’s independence. We celebrate the people of Mexico by sharing select Mexican resources for vaccination information and advocacy. Best wishes to all our friends delivering vaccinations to the people of Mexico!

Expert committees:

Advocacy groups and resources:

Helpful resources:

COVID-19 materials:

Government institutions:

Spanish translations of’s 2022–2023 influenza vaccination recipient screening forms for contraindications and precautions now available

Spanish translations of's 2022–2023 recipient screening forms, Screening Checklist for Contraindications to Inactivated Injectable Influenza Vaccination (English version) and Screening Checklist for Contraindications to Live Attenuated Intranasal Influenza Vaccination (English version), are now available for healthcare providers to print and use. 


Both forms display new footers that include a QR code on the first page. Scan the QR code to access the current document on your mobile devices.

Related Links

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Applications due September 15 to become one of several local health departments to gain access to a customized version of the vaccine information research assistant (VIRA) chatbot

Johns Hopkins University’s International Vaccine Access Center (IVAC), in collaboration with IBM Research, developed VIRA, the Vaccine Information Research Assistant chatbot that offers trustworthy answers to COVID-19 vaccine questions. Through a collaboration with the National Association of County and City Health Officials (NACCHO), VIRA is being fully customized for use by several major U.S. health departments.

To be considered, health departments serving over 500,000 people must submit the simple online application form by September 15.

Health departments selected for the VIRA X NACCHO collaboration will receive technical support to embed VIRA in their organization's web page and related health campaigns, as well as real-time data showing trending and emerging concerns surrounding COVID-19. 

Visit and share a link to VIRA on social media or your organization's website.

Related Link

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Spotlight: resources focused on enhancing clinic and practice operations

In this week's Spotlight, we summarize resources that focus on enhancing clinic and practice operations.
Our topic index on our Clinic Tools main page is a one-stop source of practical information for vaccine providers. You will find "how-to" information about vaccinating in any setting.

Our Clinic Tools: Storage and Handling main page offers printable temperature logs to monitor freezers and refrigerators. This site also includes a troubleshooting record to document the occurrence and resolution of questionable or unacceptable vaccine storage events. 

Our Clinic Tools: Documenting Vaccination main page offers forms to document vaccination or declination of vaccination, as well as various forms and checklists useful to healthcare personnel. 

Our Key Vaccination Resources for Healthcare Professionals is a 5-page annotated list of resources for people who vaccinate or oversee vaccination clinics. The document lists foundational content with which every vaccinator should be familiar, supplemental content useful after completing foundational training, and additional tools to help providers grow in vaccination expertise.

Our free downloadable book, Vaccinating Adults: A Step-by-Step Guide, is a "how to" guide that provides easy-to-use, practical information covering essential adult immunization activities.

Back to top's Influenza Vaccination Honor Roll for mandatory healthcare worker vaccination now features 1,292 organizations, including one new facility's Influenza Vaccination Honor Roll recognizes facilities that take a stand for patient safety by implementing policies for mandatory healthcare personnel influenza vaccination. There are now 1,292 organizations enrolled. Since July 21, 2022, one additional healthcare organization has been recognized.

  • UCLA Arthur Ashe Student Health & Wellness Center, Los Angeles, CA

  • Eligible organizations: Hospitals, long-term care facilities, medical practices, pharmacies, professional organizations, health departments, and other government entities
  • Requirements:
    • Your policy must require influenza vaccination for all staff
    • The application must describe measures to prevent transmission of influenza from unvaccinated personnel to patients (e.g., masking for the entire work shift)
Related Links

Journalists interview experts

Journalists seek out experts to help explain vaccines to the public and policy makers. We help the media understand and communicate the complex work vaccinators do. Here is a recent citation.

Vaccines in the news

These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination. Pages and Handouts

Reminder: posts eight printable resources to kick off the new influenza vaccination season. All now feature QR codes for easy access on mobile devices.

In addition to its very popular standing orders templates and screening checklists for contraindications, posted eight additional influenza vaccination resources updated for the 2022–2023 season. Scanning the QR code in the footer of each document gives you immediate access to that document on your mobile devices.

All of these resources are designed to support your efforts to ensure high rates of influenza vaccination this season and protect the public from the seasonal epidemic threat of influenza.

The updated resources include:

Understanding contraindications and precautions

Other influenza-related resources

 Related Links

Vaccine Information Statements posts Turkish translations of seven Vaccine Information Statements posted Turkish translations of Vaccine Information Statements (VISs) issued by CDC on August 6, 2021 and October 15, 2021. These translations were generously donated by Betül Polatdemir, MD, Losante Children’s and Adult Hospital, Ankara, Turkey, and Nur Polatdemir Çevik, Near East University, Nicosia, Cyprus.

All translations are available in print-ready PDF format. 

VIS translations in Turkish:

  • Adenovirus vaccine VIS PDF (view in English)
  • Anthrax vaccine VIS PDF (view in English)
  • Japanese encephalitis vaccine VIS PDF (view in English)
  • Multi pediatric vaccines VIS PDF (view in English)
  • Pneumococcal conjugate vaccine VIS PDF (view in English)
  • Yellow fever vaccine VIS PDF (view in English)
  • Recombinant zoster (shingles) vaccine PDF (view in English)

Related Links

Featured Resources

Order’s child, adult, and lifetime immunization record cards—wallet-sized, designed to last!'s personal immunization record cards, printed on rip-proof, smudge-proof, water-proof paper, are designed to last a lifetime. They fit in a wallet when folded. Give the record cards to your patients as a permanent personal vaccination record. 

Order Immunization Record Cards

They are sold in boxes of 250. Make bulk purchases and receive quantity discounts. For quotes on larger quantities or customizing, or to request sample cards, call 651-647-9009 or email

Notable Publications

Three recent publications in Pediatrics showcase the value of routine childhood immunization in averting vaccine-preventable diseases 

In the August 22 issue, Pediatrics published three journal articles focused on the value of routine childhood immunization and the effectiveness of vaccines in reducing vaccine-preventable diseases. 

A highlight from the results section of the "Value" article appears below.

Over the cohort’s lifetime, routine childhood immunization prevented over 17 million cases of disease and 31 000 deaths; 853 000 life years and 892 000 quality-adjusted life-years were gained. Estimated vaccination costs ($8.5 billion) were fully offset by the $63.6 billion disease-related averted costs. Routine childhood immunization was associated with $55.1 billion ([benefit-cost ratio] BCR of 7.5) and $13.7 billion (BCR of 2.8) in averted costs from a societal and healthcare payer perspective, respectively.  

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"Trends in Parents’ Confidence in Childhood Vaccines during the COVID-19 Pandemic" published in Pediatrics

In the August 30 issue, Pediatrics published Trends in Parents’ Confidence in Childhood Vaccines during the COVID-19 Pandemic. A portion of the discussion appears below. 

In this national sample, the proportion of parents concerned about the safety and side effects of routine childhood vaccines increased significantly between April 2020 and March 2022; this trend was also observed for most parent subgroups. However, parent confidence in the benefits and effectiveness of childhood vaccines remained high. Our findings underscore the important role of pediatricians in addressing parents’ concerns about childhood vaccines, as they are highly trusted by parents about vaccinations and can address vaccine hesitancy. Pediatricians should therefore ask hesitant parents about their particular concerns and be prepared to address safety concerns.

Global News

“Detection of a Highly Divergent Type 3 Vaccine-Derived Poliovirus in a Child with a Severe Primary Immunodeficiency Disorder—Chongqing, China, 2022” published in MMWR

CDC published Detection of a Highly Divergent Type 3 Vaccine-Derived Poliovirus in a Child with a Severe Primary Immunodeficiency Disorder—Chongqing, China, 2022 on September 9 in MMWR. A summary appears below.

Surveillance of acute flaccid paralysis (AFP) and wastewater (environmental) are critical to polio eradication efforts. Children with primary immunodeficiency disorders (PIDs) can excrete vaccine-derived polioviruses (VDPVs), which can hamper eradication efforts. . . .

In March 2022, a type 3 VDPV was detected in stool specimens from an infant with PID who was hospitalized in Children’s Hospital of Chongqing Medical University, China. Surveillance for poliovirus in PID patients has increased detection of immunodeficiency-related (iVDPV) cases. . . .

Integrated systematic poliovirus surveillance, including AFP, environmental, and iVDPV surveillance, is critical to the detection and containment of all polioviruses and achievement of global polio eradication.

Access the MMWR article in HTML or PDF.

Related Link

Upcoming Events

Virtual: Children's Hospital of Philadelphia hosts webinar to honor winners of the 2022 Maurice R. Hilleman Essay Contest on September 23

Children's Hospital of Philadelphia (CHOP) will host a virtual webinar titled Determination in Science on September 23 from 3:00 to 5:00 p.m. (ET). This event will celebrate the legacy of prolific vaccine developer, Dr. Maurice Hilleman, and honor the winners of the 2022 Maurice R. Hilleman Essay Contest. The winners will each receive $1,000, a certificate, a VEC prize bag, and recognition during this virtual event.

Register for the Determination in Science virtual event.

Related Links

On-demand: CDC’s “The Pink Book” chapter webinars on vaccine-preventable diseases and best practices roll out weekly. Varicella chapter now available, with CE.

CDC continues its 19-part pre-recorded webinar series to provide a chapter-by-chapter overview of the 14th edition of Epidemiology and Prevention of Vaccine-Preventable Diseases (also known as "The Pink Book").

Webinar #12, "Varicella," was released on September 13. Additional webinars will be released weekly, concluding on November 1, 2022.
No registration is required to view the sessions. Information and program details are available on CDC's Pink Book Webinars series web page.

CME, CNE, CPE, and CEU credits are available for each event. Questions about the material can be submitted to

For more upcoming events, visit our Calendar of Events.

About IZ Express

IZ Express is supported in part by Grant No. 1NH23IP922654 from CDC’s National Center for Immunization and Respiratory Diseases. Its contents are solely the responsibility of and do not necessarily represent the official views of CDC.

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Editorial Information

  • Editor-in-Chief
    Kelly L. Moore, MD, MPH
  • Managing Editor
    John D. Grabenstein, RPh, PhD
  • Associate Editor
    Sharon G. Humiston, MD, MPH
  • Writer/Publication Coordinator
    Taryn Chapman, MS
    Courtnay Londo, MA
  • Style and Copy Editor
    Marian Deegan, JD
  • Web Edition Managers
    Arkady Shakhnovich
    Jermaine Royes
  • Contributing Writer
    Laurel H. Wood, MPA
  • Technical Reviewer
    Kayla Ohlde

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