IZ Express

Issue 1877: June 3, 2026

Top Stories
 
Immunize.org Website and Clinical Resources 
    
Featured Resources
 
Notable Publications
 
Global News
 
Upcoming Events

Top Stories

AHIP member insurance plans commit to continue first-dollar vaccine coverage through 2027

AHIP (formerly American Health Insurance Plans) updated its statement on vaccine coverage, reaffirming that its member health plans will continue covering all ACIP-recommended immunizations with no cost-sharing through the end of 2027. This includes those recommended routinely or after a conversation through shared clinical decision-making. This reinforces and extends their commitment not to alter coverage through 2026 that was made in September 2025 and is consistent with the pledge to extend coverage through 2027 made by Blue Cross and Blue Shield companies in April.

This is a welcome announcement for all vaccinators. It assures healthcare professionals that they can continue to purchase, offer, and administer all ACIP-recommended vaccines with confidence that member health plans will cover those services without out-of-pocket costs to patients. AHIP noted that:

Coverage decisions for immunizations are grounded in each plan’s ongoing, rigorous review of scientific and clinical evidence and continual evaluation of multiple sources of data. These decisions reflect an operating environment shaped by federal and state laws, as well as program and customer requirements. 

Related Links


HPV vaccination: 20 years of cancer prevention in the United States

In June 2006, the FDA licensed the first HPV vaccine (Gardasil, Merck), introducing what would become one of the most successful cancer prevention tools in modern medicine. This year marks 20 years of vaccination programs that reduced the burden of HPV-related cancers across the United States and around the world.

HPV is responsible for nearly all cases of cervical cancer, as well as a large proportion of head-and-neck, anal, vulvar, vaginal, and penile cancers. Before the vaccine, these cancers claimed tens of thousands of lives each year in the United States alone. Since HPV vaccination was widely adopted, rates of HPV infection among vaccinated age groups dropped dramatically. Cervical cancer incidence rates in women age 20–31 years declined by 27% in the United States between 2016–21.

A 2-dose HPV vaccine series is recommended by AAP and AAFP to be completed before age 13 years, with the first dose given as early as age 9 years. Catch-up vaccination is recommended through age 26 years for anyone not previously vaccinated. For adults age 27–45 years, vaccination decisions should be made through shared clinical decision-making and based on individual risk. Vaccinating before exposure to the virus provides the strongest protection, making the preteen years optimal.

Immunize.org offers HPV vaccine materials, including patient handouts, talking points for addressing hesitancy, standing orders, and training resources. These tools are available on Immunize.org's Clinical Resources: HPV (Human Papillomavirus) main page. 

Additionally, Immunize.org offers HPV-related resources for the public on several of our affiliated websites:



Immunize Kansas Coalition (IKC), in collaboration with the Masonic Cancer Alliance (MCA), offers a toolkit you can use to spread awareness on how the HPV vaccine can prevent 90% of cancers caused by HPV, including cancers of the head and neck.

View the toolkit.


Measles 2026: 1,983 confirmed measles cases in 39 states; MMWR reports characteristics of hospitalized cases in the 2025 West Texas outbreak 

As of May 28, CDC reported 31 new measles cases in the previous week, reaching 1,983 confirmed measles cases for 2026. So far, 39 states have reported measles cases in 2026. Specific numbers from CDC and individual state websites differ slightly, as the frequency and timing of federal and state updates vary.

CDC published Characteristics of Patients Hospitalized with Measles During an Outbreak—West Texas, January–March 2025 in its May 28 MMWR. Analysis of the cohort of confirmed cases identified in the first 3 months of the West Texas outbreak reveals the protective effect of vaccination and the severity of illness among unvaccinated cases. A portion of the summary appears below. 

Measles is a highly contagious respiratory virus that can cause serious illness. In the United States, approximately 20% of unvaccinated persons with measles require hospitalization. . . .

During the first 3 months of a large measles outbreak in the South Plains region of west Texas (January 20–March 18, 2025), 325 measles cases were reported; 60 (18.5%) patients were hospitalized. Among 54 hospitalized patients with available medical records, all were unvaccinated or had unknown vaccination status, 91% were aged <18 years, approximately 70% had pneumonia and hypoxia, and one patient died. 


Access the MMWR article in HTML or PDF.

Below is a map from CDC showing measles cases among U.S. residents as of May 28.



Vaccine coverage rates may vary considerably from community to community within a state. Pockets of unvaccinated people can accumulate in states with high vaccination coverage, creating conditions favorable for an outbreak if measles is introduced. Vaccination remains extremely effective. Immunize.org offers measles-related resources for the public on several of our affiliated websites:

Related Links

Floods, hurricanes, tornadoes: practice your vaccine storage emergency plan now, before you need it

Power outages can create emergency conditions that damage your valuable vaccine inventory. For this reason, every site that stocks vaccines needs an emergency plan. Every VFC site is required to have one.
 

 
Find resources for emergency situations on Immunize.org's Storage & Handling main page. If your practice does not have an up-to-date plan, follow CDC’s Vaccine Storage and Handling Toolkit to create one. Plans only work when staff are trained. This month is a good time to do that. Build redundancy, flexibility, and communication into your plan. Consider:

  • Equipment backup options
  • Alternate storage options
  • Vaccine transport plans

Your plan should specify at least one facility where current staff are willing to receive and properly store your vaccine inventory if it must be relocated. CDC’s guide provides detailed instructions on monitoring temperatures during a power outage and what to do once proper storage conditions are restored.

Keep a printed copy of your plan on or near your storage unit before the power goes out!

Prevent avoidable vaccine waste by training your staff on emergency procedures, including after-hours roles and responsibilities. Then run an exercise to check understanding.

Related Links


“Introducing LetsGetRealAboutVaccines​.org (mobile view)": the new 4-minute video, part of the Orientation Video Series for Smartphones on YouTube 

This week, Immunize.org shares its latest 4-minute orientation video for people who use a smartphone to access our websites: Introducing LetsGetRealAboutVaccines.org (mobile view).

LetsGetRealAboutVaccines.org is a plain-language website that equips both families and healthcare providers to confidently support childhood immunization. It offers easy-to-read resources on childhood vaccines, tools to counter misinformation, and shareable materials. It also outlines the Act-Recommend-Motivate (ARM) approach to effective communication. Launched in 2024 by the U.S. Department of Health and Human Services, the site was transferred to Immunize.org in early 2025.

The video is available on our YouTube channel, along with our full Orientation Video Series for Smartphones. This series is a collection of short videos to help you learn how to access Immunize.org resources through your smartphone.

The full Orientation Video Series can also be found on Immunize.org's website from the "Clinical Resources" menu by clicking "Webinars & Videos," then Videos, and then Orientation Video Series

Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise.


Vaccines in the news

These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.


Immunize.org Website and Clinical Resources

Spotlight on the website: “Translations” web page

Our Translations web page provides quick access to every translated item on the Immunize.org website, including VISs and clinical resources. Translations of some documents are available in as many as 48 languages. 

On the “Translations” page, languages are listed alphabetically in a table. Next to the desired language, select either “VISs” or “Clinical Resources” to view all documents available in that language.   

Access the "Translations" page from either the “Vaccines & VISs” or “Clinical Resources” tab atop each web page. The direct link is www.immunize.org/translations.    

Patients benefit from having vaccine information in their preferred language. Immunize.org's "Translations" page makes it easier for you to meet their needs.   

Related Links


Recap: Immunize.org updates "How to Administer Intranasal and Oral Vaccinations" to remove lyophilized Rotarix (GSK) presentation

Immunize.org recently updated its resource for healthcare professionals: How to Administer Intranasal and Oral Vaccinations to remove references to the lyophilized Rotarix (GSK) that required reconstitution before administration. All lots of this presentation expired. All available Rotarix is in a fully liquid presentation that does not require reconstitution. The package insert continues to reference both formulations. 


Recap: Immunize.org updates “Standing Orders for Administering Rotavirus Vaccine to Infants” to remove lyophilized Rotarix (GSK) presentation

Immunize.org updated its Standing Orders for Administering Rotavirus Vaccine to Infants. The changes include the removal of lyophilized Rotarix to remove references to the lyophilized Rotarix (GSK) that required reconstitution before administration. All lots of this presentation expired. All available Rotarix is in a fully liquid presentation that does not require reconstitution. The package insert continues to reference both formulations. 


Summary: Immunize.org resources released in April and May 

IZ Express regularly provides readers with information about Immunize.org’s new and updated educational materials for healthcare professionals and their patients. All Immunize.org materials are free to distribute. 
 
If you missed them, the following materials were posted in recent weeks.  

Clinical Resources for healthcare professionals:   

Clinical Resources for patients: 

Web pages:    

Webinar & Videos:    


Featured Resources

Vaccinate Your Family launches minicourse, “Measles: What Everyone Needs to Know”

Vaccinate Your Family (VYF) launched a free minicourse, Measles: What Everyone Needs to Know. In this course, you will follow Elena as she learns about measles (e.g., how it is spread, who is most at risk) and how the vaccine protects children, teens, and adults. You’ll also learn how to address common myths and have supportive conversations about measles prevention.

Visit VYF University to see the minicourses, each of which is free and self-paced.

Enroll in the course.


Medscape offers educational activity on viral hepatitis; CE credit offered

Medscape Education released a curriculum, Targeting Viral Hepatitis: A Road Map for Providers, with several activities featuring expert perspectives on preventing and managing viral hepatitis. 

The activities include:

The curriculum titled "Are Your Workflows Working? Embedding Hepatitis Screening and Vaccination into Routine Care" was codeveloped and moderated by Immunize.org’s L.J Tan, PhD. A description of the curriculum appears below.

Despite advances in effective therapies, viral hepatitis rates continue to increase, especially among certain communities, identified as priority health populations. These populations include people who inject drugs (PWID), Asians and Pacific Islanders, American Indians/Alaska Natives, and non-Hispanic Black persons. Furthermore, systemic barriers, stigma, and discrimination impede access to health services for people at increased risk for viral hepatitis. These factors contribute to missed/late diagnosis, onward transmission, costly tertiary care, and reduced quality of life. This collection of CME-certified activities provides strategies to overcome barriers and deliver equitable care to further the achievement of hepatitis elimination goals in the United States and worldwide.

To earn CME, ABIM MOC, or CE credit, please click here.


Explore the www.Give2MenACWY​.org website to increase coverage for the MenACWY booster and other adolescent vaccinations

Immunize.org's www.Give2MenACWY.org website promotes the importance of adolescent vaccination, including the recommended MenACWY vaccine booster dose at age 16. Many teens are behind on vaccines, so vaccine outreach is more important than ever.

If you are looking for tools to explain meningococcal vaccine recommendations and assist in improving adolescent coverage for all recommended vaccines, view this site. Check out the many helpful tools from Immunize.org, CDC, and other organizations.

  

The website is divided into five easy-to-access sections:

The site also categorizes materials according to whether they are primarily of interest to providers, to adolescents, or to parents.

Visit Give2MenACWY.org and enjoy browsing (and deploying) its bountiful resources.

Related Links 


Notable Publications

“Hepatitis B Vaccination at Birth: Safety, Effectiveness, and Public Health Benefit” published in Pediatrics

In its April 17 issue, Pediatrics published Hepatitis B Vaccination at Birth: Safety, Effectiveness, and Public Health Benefit. The comprehensive evidence review found strong support for the safety and effectiveness of the HepB birth dose and no benefit to delaying HepB vaccination, so withholding the HepB birth dose only risks reversing a decades-long 99% reduction in pediatric hepatitis B virus infections. A portion of the video abstract appears below.



We conducted a comprehensive review of the evidence on the safety, immunogenicity, efficacy, and effectiveness of the birth dose and a delayed first dose, and of the potential role of serology for clinical decision-making. We analyzed studies of the epidemiology of HBV infection, clinical trials, systematic reviews, vaccine safety from surveillance and clinical studies, and the potential impact of revised guidelines on individual and public health. We synthesized the history of ACIP recommendations and resulting trends in HBV incidence. The review found strong evidence for the safety and effectiveness of the birth dose, and no improvement in safety or effectiveness with a delayed first dose. We found no evidence to support the use of postvaccination serology. Infant vaccination has resulted in a 99% reduction in pediatric HBV infections; we found no evidence to support a change in vaccine recommendations but identified potential health consequences.


Study finding no relation between multiple sclerosis relapse and MMR or varicella vaccination published in JAMA Network Open

In its May 20 issue, JAMA Network Open published Live Attenuated Measles-Mumps-Rubella and Varicella Vaccinations and Multiple Sclerosis Activity. A portion of the abstract appears below.

In this cohort study of nonimmunosuppressed people with MS [multiple sclerosis], vaccination with live attenuated MMR or varicella vaccine was not associated with increased risk of postvaccination relapse. The results support the administration of these vaccines when indicated and may help reassure clinicians and patients, reducing vaccine hesitancy.


Global News

Global health leaders renew pledge to immunization goals amid growing challenges

At the 79th World Health Assembly, held May 18–23, more than 70 member states and global health partners reaffirmed their commitment to the Immunization Agenda 2030 (IA2030), recognizing vaccines as one of the most powerful, cost-effective, and equitable public health tools available. Delegates stressed that strong immunization programs are the foundation of outbreak preparedness, resilient health systems, and long-term health security.

At the same time, leaders warned that progress toward IA2030 targets remains off track. Rising measles outbreaks, declining routine immunization coverage in several regions, and growing inequalities in vaccine access were cited as urgent concerns. Delegates called for renewed focus on reaching "zero-dose" children—those who never received any vaccine—particularly in fragile, conflict-affected, and hard-to-reach areas. Misinformation and declining public trust in vaccines were also highlighted as serious threats, with countries calling for stronger community engagement and health communication strategies to counter misinformation.

The World Health Organization committed to advancing the recommendations of the IA2030 Mid-Term Review and strengthening collaboration with Gavi, the Vaccine Alliance; United Nations International Children’s Emergency Fund (UNICEF); and other partners. Member states emphasized that achieving IA2030 goals will require not only scientific innovation but also sustained financing, domestic investment, political commitment, and international solidarity.


Upcoming Events

Virtual: Summit Adult Vaccine Recommendations Review (SAVRR) Council hosts public meeting on June 9 at 2:00 p.m. (ET) to describe the Council, its purpose, and procedures that guide its work

Vaccinators and vaccine recipients face unprecedented challenges as vaccination recommendations of federal, state, and healthcare professional organizations proliferate and diverge. The Summit Adult Vaccination Recommendations Review (SAVRR) Council is an independently funded committee of the National Adult and Influenza Immunization Summit (NAIIS), known as “the Summit,” dedicated to supporting implementation of evidence-based vaccination recommendations in this new environment.

The SAVRR Council will host its first public webinar online 2:00–3:00 p.m. (ET) on June 9.

The SAVRR Council is composed of a broad range of voting member organizations and observers whose representatives were screened by their organizations for conflicts of interest. All participating organizations and their representatives are listed at the SAVRR web page. Vaccine manufacturers and trade organizations do not participate in SAVRR meetings and do not provide any financial support for the Council. The objectives of the SAVRR Council are twofold:

  1. Serve as a forum to provide practical, diverse stakeholder feedback to organizations making vaccination recommendations
  2. Support clinical implementation of evidence-based vaccination recommendations by identifying challenges to implementation and recommending strategies to increase affordable access and vaccine use
Working meetings of the SAVRR Council occur monthly, with quarterly public meetings planned. The initial 1-hour public webinar will describe its purpose and the procedures that guide its work. In addition, it will review the SAVRR Council’s preliminary recommendations for effective implementation of fall respiratory vaccination recommendations. The meeting will conclude with discussion of plans for future open meetings and opportunities for ongoing engagement. Immunize.org administers and serves as the fiscal agent for the NAIIS and the SAVRR Council.

Register for the meeting.

Related Links
Virtual: Register for Immunize.org Website Office Hours. Join a 30-minute discussion about our Vaccine Confidence & Addressing Concerns web content on June 10 at 4:00 p.m. (ET) or June 11 at 12:00 p.m. (ET). Recorded sessions archived.

To learn simple tips and tricks for using our websites efficiently, please register for our next set of Website Office Hours on Wednesday, June 10, at 4:00 p.m. (ET) or Thursday, June 11, at 12:00 p.m. (ET). The same content will be covered in both sessions.

We will open each 30-minute session with a short, live demonstration on navigating our Vaccine Confidence & Addressing Concerns website section. You can submit questions when you register or live on Zoom during the session.

Register today for Immunize.org Website Office Hours (content is the same for both):

The archive of previous Website Office Hours content is posted at Immunize.org’s "Webinars & Videos" page.

Mark your calendar for future Immunize.org Website Office Hours.


For more upcoming events, visit our Calendar of Events.

About IZ Express

IZ Express is supported in part by Grant No. NH23IP922654 from CDC’s National Center for Immunization and Respiratory Diseases. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.

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ISSN 2771-8085

Editorial Information

  • Editor-in-Chief
    Kelly L. Moore, MD, MPH
  • Managing Editor
    John D. Grabenstein, RPh, PhD
  • Associate Editor
    Sharon G. Humiston, MD, MPH
  • Writer/Publication Coordinator
    Taryn Chapman, MS
    Courtnay Londo, MA
  • Style and Copy Editor
    Marian Deegan, JD
  • Web Edition Managers
    Arkady Shakhnovich
    Jermaine Royes
  • Technical Reviewer
    Kayla Ohlde

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