Issue 1819: June 18, 2025

On June 9, FDA approved a second long-acting RSV preventive antibody, clesrovimab-cfor (Enflonsia, Merck). It is indicated for the prevention of RSV lower respiratory tract disease in neonates and infants up to age 12 months who are born during or entering their first RSV season.

Related Links

• FDA: Enflonsia package insert (PDF)
• FDA: Novel Drug Approvals for 2025 web page
• Immunize.org: Package Inserts and FDA Product Approvals main page

On June 12, FDA expanded the indicated age range for mResvia (RSV vaccine, Moderna). Previously, mResvia was indicated for the prevention of lower respiratory tract disease (LRTD) caused by RSV solely in those age 60 years and older. This approval expands the indication to include adults age 18 through 59 years who are at increased risk for LRTD due to RSV.

Related Links

• FDA: mResvia web page
• FDA: mResvia package insert (PDF)
• FDA: Novel Drug Approvals for 2025 web page
• Immunize.org: Package Inserts and FDA Product Approvals main page

Studying wastewater can help health departments track and prevent disease from circulating in the community. Stanford University, in partnership with Emory University, developed WastewaterSCAN to monitor infectious diseases through municipal wastewater systems to inform public health responses at a local, regional, and national level. The information can be viewed on the WastewaterSCAN Dashboard web page.

WastewaterSCAN shares methods and data with the CDC National Wastewater Surveillance System (NWSS) program. NWSS works with partners to test and monitor wastewater for viruses and bacteria so communities can act quickly to prevent the spread of infections.

Pathogens tracked with this project include Candida auris, enterovirus D68, hepatitis A, human metapneumovirus, influenza A, influenza B, measles, mpox clade Ib, mpox clade II, norovirus, RSV, and SARS-CoV-2.

View the WastewaterSCAN Dashboard.

Related Links

• WastewaterSCAN website
• WastewaterSCAN Dashboard web page
• CDC: National Wastewater Surveillance System main page

NFID posted a compilation of statements from medical, pharmacy, nursing, public health, and other professional and community associations describing the crucial role ACIP played in the United States since the 1960s. NFID will update this collection as it learns of additional partner statements.   

As of June 12, CDC reported 1,197 confirmed measles cases in 2025 in 34 states, including the first cases reported this year in Arizona. The states with the most confirmed cases in 2025 are Texas (777, 64.9%) and New Mexico (81, 6.7%). Among confirmed cases, 12% were hospitalized, with 29% younger than age 5 years.

CDC only requires reporting of laboratory-confirmed measles cases. Cases without laboratory testing for confirmation are not included in these numbers. Actual numbers of cases are, therefore, higher than confirmed case counts.

A map of 2025 measles cases in the contiguous United States, as of June 10, from the Johns Hopkins International Vaccine Access Center appears below. The U.S. Measles Tracker website includes state and county-level data.

CDC updated its Travelers' Health: Global Measles web page to encourage all international travelers to be fully vaccinated before travel. Additionally, CDC offers resources for communities experiencing a measles outbreak including infographics for families, images to help clinic personnel identify cases, guidance for caring for patients with measles, and a Be Ready for Measles communication toolkit. Spanish-language resources are now available on the toolkit page. 



Related Links

• CDC: Measles Cases and Outbreaks main page
• CDC: Be Ready for Measles Toolkit
• Center for Outbreak Response Innovation: Measles Outbreak Response main page
• Immunize.org: Vaccines A–Z: Measles main page
• Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Children and Teens (PDF)
• Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Adults (PDF)
• Immunize.org: Ask the Experts: MMR (Measles, Mumps, and Rubella) web page

Immunize.org's Influenza Vaccination Honor Roll recognizes facilities that take a stand for patient safety by implementing policies requiring vaccination for healthcare personnel. Immunize.org welcomes Jefferson Healthcare – Port Townsend, Port Townsend, WA, to our honor roll.

Eligibility

• Eligible organizations: hospitals, long-term care facilities, medical practices, pharmacies, professional organizations, health departments, and other government entities
• Requirements:
  • Your policy must require influenza vaccination for all staff
  • The application must describe measures to prevent transmission of influenza from unvaccinated personnel to patients (e.g., masking for the entire shift)

• Immunize.org: Honor Roll Honorees: Influenza
• About the Influenza Vaccination Honor Roll

This week, our featured episode from the Ask the Experts Video Series is titled How Does PCV7 Receipt Factor into Decisions About Adult Pneumococcal Vaccination? The video describes CDC's recommendation that, when calculating the number of prior pneumococcal doses, any PCV7 doses be disregarded.

The 1-minute video is available on our YouTube channel, along with our full collection of quick video answers to popular Ask the Experts questions.

Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise.

• Facebook at ImmunizeOrg
• Instagram at ImmunizeOrg
• LinkedIn at ImmunizeOrg
• YouTube at ImmunizeOrg

These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.

• CBC: 6 Infants Born with Congenital Measles from Unvaccinated Mothers in Ontario Since Last Fall (6/9/25) 
• CIDRAP: Studies Show Safety, Low Side-Effect Profile of COVID Vaccines in Pregnancy (6/9/25) 
• Science: NIH Terminates Network Aimed at Stopping Pandemics Before They Start (6/9/25)
• ABC: US Measles Cases Nearing 30-Year High (6/6/25)  
• Politico: WHO Sounds the Alarm as US Measles Cases Mount (6/6/25)  

The American Academy of Pediatrics released four free Red Book Online Webinars focused on measles, including:

• Spotting a Threat: Measles in Immunocompromised Children (24:40)
• Infection Prevention & Control for Measles (14:56)
• The Use of Vitamin A in the Management of Measles (5:35)
• Identifying and Diagnosing Measles in the Pediatric Setting (two parts: 5:21, 9:44) 

Earlier in 2025, the webinar series focused on “Mpox Basics.”

View the webinars.

To help with safe travel planning, use these three sets of travel resources.

Visit CDC's Travelers' Health website to view information on more than 50 topics to help in deciding what vaccines, medications, and other measures are needed to prevent illness during travel.



CDC's Travelers' Health: Traveler Advice web page includes information grouped by reasons for travel, travelers with special considerations, general tips, tips during travel, and tips after travel.



Immunize.org's Travel Vaccines main page makes it easy to access current travel vaccination guidance from authoritative sources. It offers direct links to popular CDC and nongovernment resources.

The U.S. State Department allows travelers to register their itinerary and receive emergency messages via the Smart Traveler Enrollment Program.



Related Links

• CDC: Travelers' Health web page
• CDC: Travelers' Health: Traveler Advice web page
• CDC Yellow Book: Health Information for International Travel
• Immunize.org: Travel Vaccines main page
• U.S. Department of State: Smart Traveler Enrollment Program

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Keep the 2025 immunization schedule at your fingertips! Order laminated 2025 U.S. adult immunization schedule booklets from Immunize.org.

Laminated booklets of the 2025 U.S. adult immunization schedule are available in the Immunize.org shop. The 2025 child and adolescent schedule booklets sold out.

The schedules are available online as PDFs from CDC at no cost. Immunize.org’s laminated booklets are ideal for use in any busy healthcare setting where vaccines are given.

   

Adult Booklets
1 copy: $10.00
2–4 copies: $9.50 each
5–19 copies: $8.50 each
20–99 copies: $7.50 each
100–499 copies: $6.00 each
500–999 copies: $5.00 each
1,000–1,999 copies: $4.00 each
2,000+ copies: $3.25 each

Visit the Shop Immunize.org: Laminated Schedules web page to view images and order today!

For additional information, call 651-647-9009 or email admininfo@immunize.org.

Related Links

• Immunize.org: Laminated Adult Immunization Schedules (19 and older) web page
• Immunize.org: Shop Immunize.org main page 

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Need to teach vaccine administration? Use Immunize.org’s Vaccinating Adults: A Step-by-Step Guide—free to download 

Download Immunize.org’s free 142-page book on adult vaccination to help build your program and train your team: Vaccinating Adults: A Step-by-Step Guide (Guide).

 

This thorough "how to" guide on adult vaccination provides easy-to-use, practical information covering all essential activities. It helps vaccine providers enhance their existing adult vaccination services or introduce them into any clinical setting.

The Guide is available to download/print either by chapter or in its entirety free of charge. The National Vaccine Program Office and CDC both supported the development of the Guide and provided early technical review.

The Guide is a valuable resource to assist providers in increasing adult vaccination rates. Be sure to get a copy today!

Please note: this guide was produced in 2017, before the COVID-19 era, and reflects the recommendations of that time.

Related Links

• Vaccinating Adults: A Step-by-Step Guide main page, permitting download of entire Guide (142 pages, PDF)
• View the table of contents and individual chapters (PDF):
  • Table of Contents
  • Step 1: Getting Started
  • Step 2: Setting Up for Vaccination Services
  • Step 3: Vaccine Storage and Handling
  • Step 4: Deciding Whom to Vaccinate
  • Step 5: Administering Vaccines
  • Step 6: Documentation and Related Issues
  • Step 7A: Financial Considerations
  • Step 7B: How to Bill for Adult Immunizations
• Immunize.org’s Clinical Resources on adult immunization

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Notable Publications

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“Measles in Pregnancy” published in Canadian Medical Association Journal 

In the June 9 issue, the Canadian Medical Association Journal published Measles in Pregnancy, a practice summary. The authors briefly explain five key points:

• Measles in pregnancy poses serious maternal and fetal risks
• Intravenous immunoglobulin (IVIG) can reduce the risk of infection or lessen the severity of measles during exposed, susceptible pregnancies
• Special care considerations are necessary for people admitted to hospital with measles, given its airborne transmission and high infectivity
• Maternal infection in the 2 weeks before delivery can lead to severe congenital infection
• Ensuring everyone of reproductive age is up to date with measles vaccination is crucial to prevent complications during pregnancy and after delivery

An accompanying editorial, Pregnant and Bearing the Burden of Measles Outbreaks in Canada, points out:

Even in well-resourced settings, measles has devastating consequences. During an outbreak in Italy in 2017, researchers followed 24 pregnant women with measles infections, among whom were 6 (25.0%) premature deliveries; 4 (16.7%) miscarriages and fetal deaths; and 20 (80.0%) maternal hospitalizations from complications related to measles, most frequently pneumonia.        

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Upcoming Events

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Today, virtual: NFID hosts webinar titled “Protecting Patients Before Travel” on June 18 at 1:00 p.m. (ET)

NFID will host a webinar titled Protecting Patients Before Travel at 1:00 p.m. (ET) on June 18. The panel includes NFID Medical Director Robert H. Hopkins Jr., MD; Chapman University School of Pharmacy Professor Jeffery A. Goad, PharmD, MPH; and Harvard Medical School Associate Professor Lin H. Chen, MD. Speakers will review current recommendations for travelers and share implementation strategies.

CME and CNE credit are available. There is no fee to participate in this activity, but preregistration is required.

Register for the webinar.



NFID hosts monthly webinars to increase awareness of the importance of infectious disease prevention and treatment. CME, CNE, and CPE credits are available for select recordings. View all archived NFID webinars.

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Virtual: Association of Immunization Managers hosts webinar titled “Correlation and Causation: Understanding and Debunking Claims Linking Vaccines and Autism” on June 24 at 2:00 p.m. (ET) 

The Association of Immunization Managers (AIM) will host a webinar titled Correlation and Causation: Understanding and Debunking Claims Linking Vaccines and Autism at 2:00 p.m. (ET) on June 24. Michelle Fiscus, MD, FAAP, AIM’s chief medical officer, will give an overview of autism spectrum disorder and how the vaccine-autism claim emerged and persists. Dr. Fiscus will summarize key studies that debunked the claim and share communication tools for immunization programs and healthcare providers to engage families and communities in informed conversations.

Register for the webinar. 

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Virtual: Public Health Communications Collaborative hosts webinar titled "Building Your Public Health Comms Toolkit: Communications Planning on a Budget" on June 25 at 3:30 p.m. (ET) 

The Public Health Communications Collaborative (PHCC) will host a webinar titled Building Your Public Health Comms Toolkit: Communications Planning on a Budget at 3:30 p.m. (ET) on June 25. During this webinar, public health and communications experts will provide tools, tips, and stories that support effective public health campaigns on small or nonexistent budgets. Attendees will learn more about:

• Building a free or low-cost toolkit for content planning, organization, and distribution of key public health messages
• How new partnership approaches can amplify your messages where people need to hear them
• Free or low-cost communication channels that can provide clarity, connection, and better community health outcomes

Register for the webinar. 

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Virtual: HPV Vaccine Acceleration Program Partners Initiative Consortium hosts webinar titled “Expanding Reach: Insights from Multi-Country Approaches to HPV Vaccination for Out-of-School Girls” on June 25 at 9:00 a.m. (ET) 

The HPV Vaccine Acceleration Program Partners Initiative (HAPPI) Consortium will host a webinar titled Expanding Reach: Insights from Multi-Country Approaches to HPV Vaccination for Out-of-School Girls at 9:00 a.m. (ET) on June 25. During the webinar, learn how programs are reaching girls missed by school-based HPV vaccination efforts. The webinar will explore five themes: characterization of out-of-school girls; how programs identify such girls; program coordination; community awareness and demand generation; and delivery strategies.

Register for the webinar. 

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Virtual: Watch upcoming June 25–27 ACIP meeting with discussion of several vaccine recommendations, including COVID-19, HPV, influenza, meningococcal, and RSV

CDC is scheduled to convene the ACIP on June 25–27. Recommendation votes are scheduled for COVID-19, HPV, influenza, meningococcal, and RSV vaccines. Additionally, the agenda includes discussion of vaccines targeting anthrax, chikungunya, cytomegalovirus (CMV), Lyme, and pneumococcal diseases.

After dismissing 17 members of ACIP, HHS announced eight new members.

No registration is required to watch webcasts of live ACIP meetings or listen via telephone. Opportunities for written or oral public comment are described on the website.

View meeting information.



Related Links

• CDC: ACIP main page for access to webcast, agendas
• CDC: ACIP: Meeting Information for presentation slides, content from previous meetings, and information about future meetings

View the agenda.

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Virtual: New Jersey Chapter of American Academy of Pediatrics hosts webinar, “From Inoculation to Innovation: The Historical and Ethical Journey of Vaccination,” on June 30 at 3:00 p.m. (ET)  

The New Jersey Chapter of American Academy of Pediatrics (AAP) will host a webinar titled From Inoculation to Innovation: The Historical and Ethical Journey of Vaccination at 3:00 p.m. (ET) on June 30. The speakers will be David J. Cennimo, MD, FACP, Associate Professor of Medicine and Pediatric Infectious Disease, Rutgers University, and Luis Alzate-Duque, MD, MPH, Assistant Professor of Medicine and Pediatrics, Rutgers New Jersey Medical School. Learning objectives include:

• Exploring the historical milestones in vaccine development from early inoculation to modern immunization strategies
• Understanding the impact of vaccines on global health outcomes and economic savings, especially in childhood mortality and disease prevention
• Examining historical and ongoing opposition to vaccines, exploring the roots of vaccine hesitancy and organized anti-vaccination movements
• Discussing the ethical challenges related to vaccine mandates, informed consent, research practices, and global equity
• Evaluating the public health implications of vaccine acceptance and refusal, using predictive modeling and real-world case studies

Register for the webinar.

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For more upcoming events, visit our Calendar of Events.