What adverse events can be expected following HPV vaccine?

In clinical trials of 9vHPV involving more than 15,000 subjects, the most common adverse event was injection site pain, which was reported in about 90% of recipients. Other local reactions, such as redness and/or swelling, were reported in about 40% of recipients. Fever was less common, reported by about 6% of recipients. The rates and severity of adverse reactions following each dose of 9vHPV were similar between boys and girls.