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  • Administering Vaccines
  • General Issues

If I need to give more than 1 injection in a muscle, are certain vaccines best given at different anatomic sites?

Since DTaP and pneumococcal conjugate (PCV) are the vaccines most likely to cause a local reaction, it is prudent to give DTaP and PCV in separate limbs (if possible), so there is no confusion about which vaccine caused the reaction.

Last reviewed: December 28, 2022

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