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  • COVID-19
  • Vaccine Safety

How long should patients be observed for signs of an immediate allergic reaction following vaccination with a COVID-19 vaccine?

In accordance with general best practices for vaccination, all people should be observed for at least 15 minutes after vaccination for signs of an immediate allergic reaction.

If you vaccinate a person who has a precaution to COVID-19 vaccination, you should consider a 30-minute observation period following vaccination. See CDC’s detailed considerations for people with a history of allergies or allergic reactions:

Last reviewed: October 26, 2023

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