May I use the 2024–2025 Formula Novavax COVID-19 protein subunit vaccine in people who are previously vaccinated?

Yes. The 2024–2025 formula Novavax vaccine is an option for any person age 12 years or older who is unvaccinated or was previously vaccinated with any COVID-19 vaccine and is due for a 2024–2025 updated vaccination. Any person age 12 years or older who has never had a dose of any COVID-19 vaccine should receive two doses of 2024–2025 Formula Novavax vaccine, administered 3 to 8 weeks apart, as a primary series. 

Previously vaccinated adults age 65 years and older should receive one dose of 2024–2025 Formula Novavax COVID-19 vaccine and an additional dose of any current COVID-19 vaccine product 6 months (minimum interval 2 months) later.  

Previously unvaccinated adults age 65 years and older who are not immunocompromised require a 2-dose primary series with the current 2024–2025 Formula Novavax vaccine and should receive an additional (third) dose of any 2024–2025 Formula COVID-19 vaccine product 6 months (minimum interval 2 months) after the second primary series dose. 

Novavax recipients with moderate to severe immunocompromise being vaccinated for the first time should receive a third dose at least 2 months following the second dose in their primary series and may receive subsequent additional doses at the discretion of their healthcare provider, in consideration of their individual preferences and circumstances. 

Additional details from FDA are available: www.fda.gov/vaccines-blood-biologics/coronavirus-covid-19-cber-regulated-biologics/novavax-covid-19-vaccine-adjuvanted.