I have a 24-month-old patient with a complement component deficiency who received a dose of DTaP at 23 months of age and then received a dose of Menactra (MenACWY-D) two weeks later. Do I need to repeat the dose of Menactra?

No. Even though ACIP recommends that Menactra (MenACWY-D) should be given either before, at the same visit, or at least 6 months after DTaP, there is no evidence to support repeating the dose of Menactra. A child with a complement component deficiency should still receive a second dose of MenACWY vaccine at least 8 weeks after the first dose. In this case, if the 2nd dose also will be Menactra, it should wait until the child is 29 months old (6 months after the dose of DTaP).