How should we administer both pneumococcal vaccines (PCV13 and PPSV23) to our high-risk pediatric patients?

All children with risk factors for pneumococcal disease or its complications should be vaccinated with PPSV23 beginning at age 2 years. If they are age-eligible and are due for a dose of PCV13, give PCV13 first and then wait 8 weeks before giving PPSV23. For more information on vaccination of high-risk pediatric patients, see pages 26–27 of the ACIP statement at www.cdc.gov/mmwr/pdf/rr/rr5911.pdf.