ACIP recommends that microbiologists who work with meningococcal isolates in a laboratory receive both MenB and MenACWY vaccines. MenB can be given at the same time as any other vaccine. You can administer either two doses of Bexsero (MenB-4C) 4 weeks apart, or three doses of Trumenba (MenB-FHbp) on a 0-, 1–2-, and 6-month schedule.
Because protective antibody levels begin to wane within 1–2 years after completing the primary series, ACIP recommends a booster dose of MenB one year after completing the primary series, followed by a booster dose every 2–3 years thereafter, as long as risk remains. MenB vaccine brands work differently and are not interchangeable. All doses, including booster doses, should be of the same brand. If the brand of the primary series is not known or is not available, restart the primary series with the available brand.