Rotavirus
2009

New Insights Could Help Shield Babies from Diarrhea Bug

HealthDay News
July 17, 2009
"The incidence of rotavirus infection, a major cause of infant illness in the United States, could be drastically reduced by a better understanding of when and where infections are likely to spread and by the wide use of new vaccines, new research suggests..."

Rotavirus: Every Child Should Be Vaccinated Against Diarrheal Disease, W.H.O. Says

New York Times
June 9, 2009
"The World Health Organization recommended last week that the vaccine against rotavirus, a diarrheal disease that kills 500,000 children a year, be given to every child in the world. More than 85 percent of those deaths are of poor children in Africa, Asia and Latin America, and the W.H.O. endorsement allows donor money to be used for the vaccine..."
Rotavirus Vaccines -- Early Success, Remaining Questions
New England Journal of Medicine
March 12, 2009
"In 2006, the results of pivotal clinical trials of two new rotavirus vaccines — RotaTeq (Merck) and Rotarix (GlaxoSmithKline) — were published, and high efficacy (85 to 98%) against severe rotavirus diarrhea was reported for both products.1,2 Perhaps even more important, neither vaccine was associated with intussusception, an adverse effect that had led to the withdrawal of another rotavirus vaccine — RotaShield, made by Wyeth-Lederle — from the U.S. market in 1999. The rapid resurgence of rotavirus vaccines after the abrupt and devastating setback associated with the withdrawal of RotaShield was remarkable, reflecting the commitment of the public health community and the vaccine industry to preventing this most common cause of severe diarrhea in children. In the United States, rotavirus causes an estimated 3 million cases of diarrhea each year; medical attention is sought for more than 500,000 children, and 60,000 to 70,000 are hospitalized. In the developing world, the disease kills more than half a million children annually..."
2008
Rotavirus Vaccine a Success Story
WebMD
October 27, 2008
"A vaccine against rotavirus, an infectious disease that causes potentially deadly diarrhea in infants, has led to a remarkable drop in hospitalizations and visits to the emergency room, researchers say. Since it was introduced two years ago, the RotaTeq vaccine has cut the number of new rotavirus cases by 66% to 100%, according to a number of studies. There's even evidence the vaccine reduced spread of the infectious disease to children who were not immunized, the researchers say..."
Vaccine Brings Dramatic Drop in Rotavirus
Pittsburgh Post-Gazette
October 26, 2008
"A vaccine against rotavirus, the leading cause of diarrhea in infants, has led to a dramatic drop in hospitalization and emergency room visits since it came on the market two years ago, doctors reported yesterday. A bonus: The vaccine seems to be preventing illness even in unvaccinated children by cutting the number of infections in the community that kids can pick up and spread..."
New Vaccine May Account for Less Severe Rotavirus Season
Washington Post
June 25, 2008
"A recent vaccine for rotavirus -- a leading cause of vomiting and diarrhea in infants and children -- may account for this year's less severe season, the U.S. Centers for Disease Control and Prevention said Wednesday. The highly contagious virus is shed in the stools of infected people and is transmitted by contaminated hands and objects. Children can transmit the virus before and after they become sick with diarrhea..."
US Panel Endorses 2nd Vaccine for Kids' Virus
The Associated Press
June 25, 2008
"A federal advisory panel has endorsed a second vaccine to combat a common and potentially fatal virus that causes diarrhea and vomiting in children. The new two-dose vaccine for infants, made by GlaxoSmithKline, was licensed by the Food and Drug Administration in April. The vaccine advisory committee agreed Wednesday that it should be added to the recommended vaccines for infants, as well as the three-dose vaccine made by Merck & Co. and approved in 2006..."
Op-ed: Joining Forces to Combat Global Illness
Author:Jean Stephenne, president of GlaxoSmithKline Biologicals
Seattle Post-Intelligencer
June 19, 2008
"A recent vaccine for rotavirus -- a leading cause of vomiting and diarrhea in infants and children -- may account for this year's less severe season, the U.S. Centers for Disease Control and Prevention said Wednesday. The highly contagious virus is shed in the stools of infected people and is transmitted by contaminated hands and objects. Children can transmit the virus before and after they become sick with diarrhea..."
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