Human Papillomavirus (HPV)
2009

CDC: 1 in 3 Teen Girls Got Cervical Cancer Vaccine

USA Today
September 18, 2009
"One in three teenage girls have rolled up their sleeves for a vaccine against cervical cancer, but vaccination rates vary dramatically between states, according to a federal report released Thursday. The highest rates were in Rhode Island, New Hampshire and Massachusetts, where more than half of girls ages 13 through 17 got at least one dose of the three-shot vaccination. The lowest rates were in Mississippi, Georgia and South Carolina, where fewer than 20% got at least one shot..."

FDA Panel Urges HPV Vaccine Be Given to Boys

CNN
September 9, 2009
"Boys may soon be able to get Gardasil, the vaccine given to girls and young women to prevent infection by four types of human papillomavirus. Gardasil, a vaccine against human papillomavirus, would be given to boys exactly as it is to girls. A Food and Drug Administration advisory committee voted Wednesday to recommend that the vaccine be made available to boys and young men aged 9 to 26 for protection against genital warts caused by HPV..."

How Safe Are New Vaccines For H1N1, HPV?
Listen to the Story [3 min 58 sec]

NPR
August 25, 2009
"School officials in Washington, D.C., are requiring all school girls 13 and older get vaccinated for Human Papillomavirus (HPV), which can lead to cervical cancer. And a vaccine for the swine flu - also known as H1N1 virus - is expected to become available later this fall. Guest host Jennifer Ludden talks with Dr. Paul Offit, Chief of Infectious Diseases at The Children's Hospital of Philadelphia, about the safety of the new vaccines. Dr. Offit also has the latest on plans to conduct a mass immunization for Swine flu – which is expected to be a national program of historic proportions..."

HPV Vaccine Could Prevent Many Penile Cancers

Health Day News
August 25, 2009
"The human papillomavirus (HPV) causes about half of penile cancer cases in the world, and giving vaccines to males could greatly reduce the incidence of the disease, a new study suggests. Penile cancer remains rare, accounting for less than 1 percent of adult male cancers in North America and Europe, but that rate jumps to as high as 10 percent in Africa and Asia, according to Spanish researchers reporting online Aug. 25 in the Journal of Clinical Pathology. More than 26,300 cases of penile cancer are thought to occur around the world each year..."

U.S. Health Officials Back Safety of Merck Vaccine

Reuters
August 20, 2009
"U.S. health officials again backed on Thursday the safety of Merck & Co Inc's vaccine to prevent infection by a virus that causes most cases of cervical cancer. The Gardasil vaccine 'continues to be safe and effective, and its benefits continue to outweigh its risks,' the Food and Drug Administration and the Centers for Disease Control and Prevention said in a statement. Gardasil protects against infection with four strains of the human papillomavirus (HPV), a common sexually transmitted virus that causes genital warts and most cases of cervical cancer..."

Study Weighs Risks of Vaccine for Cervical Cancer

New York Times

August 18, 2009
"The new vaccine designed to protect girls and young women from cervical cancer has a safety record that appears to be in line with that of other vaccines, a government report has found. Some serious complications occurred, including at least 20 deaths and two cases of Lou Gehrig's disease, but they were not necessarily caused by the vaccine, the study said..."

WHO Approves Cervical Cancer Vaccine Cervarix

USA Today
July 9, 2009
"The World Health Organization has approved a second cervical cancer vaccine, this one made by GlaxoSmithKline, meaning U.N. agencies and partners can now officially buy millions of doses of the vaccine for poor countries worldwide. GlaxoSmithKline PLC said in a statement Thursday the approval would help speed access to Cervarix globally..."

New Evidence Supports HPV Vaccine

Forbes
July 7, 2009
"The human papillomavirus (HPV) vaccine is highly effective at preventing precancerous cervical lesions that can lead to cervical cancer, a new study shows. The researchers also found that the HPV-16/18 AS04-adjuvanted vaccine also appears to protect against other cancer-causing HPV types closely related to HPV-16/18, most notably HPV-31 and HPV-45. The study of women aged 15 to 25, who received three vaccine doses over six months, found that it was as much as 98 percent effective against HPV-16/18, and between 37 percent and 54 percent effective against 12 other cancer-causing HPV types..."

FDA Strengthens Warnings on Gardasil

Wall Street Journal
June 10, 2009
"The Food and Drug Administration on Wednesday strengthened warnings on Merck & Co.'s Gardasil vaccine about fainting after receiving reports of 'traumatic injuries' among some vaccine recipients. In a posting aimed at health-care professionals posted on the agency's Web site, the FDA said all vaccine recipients should remain seated or lying down and be closely observed for 15 minutes following vaccination, 'to prevent falls and injuries.' Gardasil was approved in June 2006 and is designed to protect against four strains of the human papillomavirus, or HPV, two of which account for about 70% of cervical-cancer cases. It's recommended that girls ages 11 to 12 receive the vaccine in a three-dose series before they are sexually active, and it coincides with recommendations on other vaccines..."

Booster Shots: HPV may benefit older women

Los Angeles Times
June 1, 2009
"A vaccine to prevent infections of four strains of human papilloma virus is available to girls ages 9 to 26. The 2006 approval of the vaccine was heralded because some strains of HPV can cause cervical cancer. Studies have continued, however, on whether the vaccine may be useful for other groups of people, such as boys and older women. A study published today in the Lancet suggests that women ages 25 to 45 not already infected with HPV may be protected by the vaccine as well..."

Most mothers oppose HPV vaccination for younger daughters

Reuters
May 26, 2009
"New research suggests that most mothers in the US do not intend to have a 9- to 12-year-old daughter vaccinated against human papillomavirus (HPV), even though the national HPV vaccination guidelines specifically target 11- to 12-year-old girls. HPV vaccination has been advocated as a key means of preventing cervical cancer. According to the report in the June issue of Pediatrics, 48% of mothers intended to have a 9- to 12-year-old daughter vaccinated against HPV. This contrasts with the intention to vaccinate 68% and 86% of girls 13 to 15 and 16 to 18 years of age, respectively..."

Bill to Give Kids Information on HPV Vaccine Approved

St. Louis Post-Dispatch
May 12, 2009
"Conservative and liberal groups have teamed up to support a bill that would give parents of public school girls information about a controversial vaccine that could help prevent cervical cancer. The bill, which passed the Senate last week by a 28-5 vote, would give information about the HPV vaccine to parents of sixth-grade girls enrolled in public school. It would also pay for the $120 vaccine in some cases. It does not mandate that parents vaccinate their daughters with Gardasil, which is intended to prevent the human papillomavirus, HPV, a sexually transmitted virus that has been linked to cervical cancer..."
Oregon House OKs Bill to Fight Cervical Cancer
The Oregonian
April 15, 2009
"Health insurers would be required to cover the cost of a cervical cancer vaccine given to girls and young women if a bill that passed the Oregon House on Wednesday becomes law. The vaccine, known as the HPV vaccine, was approved by the U.S. Food and Drug Administration in 2006 for girls and young women ages 9 to 26. It is intended to be administered in three shots to girls before they become sexually active as a means to combat the human papilloma virus, linked to cervical cancers..."
The Checkup; Circumcise Your Son?
The Washington Post
March 31, 2009
"There's new evidence that men who are circumcised are less likely to get infected with sexually transmitted viruses, according to a study published in the New England Journal of Medicine. Previous research had found that men who were circumcised were 50 to 60 percent less likely to get infected with the AIDS virus. Now, researchers have found that circumcision also significantly reduces a man's risk of being infected with the herpes simplex virus type 2 (HSV-2), which causes genital herpes, and the human papillomavirus (HPV), which can cause genital warts in men and cervical cancer in women. Researchers at the Johns Hopkins University Bloomberg School of Health in Baltimore..."
Circumcision Is Found To Curb Two S.T.D.'s
New York Times
March 26, 2009
"Male circumcision, already shown to reduce the incidence of H.I.V. infection in men, also reduces transmission of both herpes simplex virus Type 2 and human papilloma virus, a study has found. According to the Centers for Disease Control and Prevention, at least 45 million people in the United States ages 12 and older have had herpes, or H.S.V.-2, the incurable infection that can cause recurrent painful genital warts. About 20 million are currently infected with human papilloma virus, or H.P.V., which causes various genital cancers, including most cervical cancers. There is no treatment or cure for H.P.V., but there is a vaccine now licensed only for girls and women. The study, a randomized clinical trial published Thursday in The New England Journal of Medicine, assigned more than 3,000 uncircumcised Ugandan men who were not infected with H.S.V.-2 to undergo immediate circumcision or to be circumcised 24 months from the start of the investigation. A subgroup was similarly evaluated for H.P.V. infection..."
A Vaccine Debate Once Focused on Sex Shifts as Boys Join the Target Market
Washington Post
March 26, 2009
"When a vaccine designed to protect girls against a sexually transmitted virus arrived three years ago, the debate centered on one question: Would the shots make young girls more likely to have sex? Now the vaccine's maker is trying to get approval to sell the vaccine for boys, and the debate is focusing on something else entirely: Is it worth the money, and is it safe and effective enough? "We are still more worried about the promiscuity of girls than the promiscuity of boys," said Susan M. Reverby, a professor of women's studies and medical history at Wellesley College..."
HPV Data May Aid Vaccine's Effectiveness
HealthDay News
March 24, 2009
"The majority of invasive cervical cancers in New Mexico in the 1980s and 1990s contained DNA from human papillomavirus type 16 (HPV16) and HPV type 18 (HPV18), says a new study. It also found that women diagnosed with HPV16- or HPV18-positive cancers were an average of five years younger than those diagnosed with cancers associated with other HPV types..."
Most Women Willing to Get HPV Vaccine
United Press International
March 11, 2009
"Most women are willing to be vaccinated against the human papillomavirus and have their daughters and sons vaccinated, as well, U.S. researchers say. The study, published in the journal Gynecologic Oncology, also found that Latino women are just as likely, if not more so, to accept HPV vaccine as non-Latinos. 'Since the incidence and mortality of cervical cancer are higher among Latino women in the United States, we were interested in whether the vaccine acceptance rate in this high-risk population was the same as for non-Latino women,' Dr. Marcela del Carmen of the Massachusetts General Hospital Cancer Center who was the senior author, said in a statement..."
Cervical Cancer Outcomes Differ According to HPV Genotype
Reuters Health
March 3, 2009
"Invasive cervical cancer outcomes are worse with high-risk human papillomavirus (HPV) genotypes than with intermediate-risk HPV genotypes, according to a report in the February 15th International Journal of Cancer. 'HPV genotypes 16 and 18 represent 70% of invasive carcinomas (this figure is to be kept in mind in the perspective of prophylactic anti HPV16/18 vaccination), and 4% of invasive carcinomas are HPV-negative (a figure to keep in mind in the perspective of screening intra-epithelial neoplasia via virological detection),' Dr. Xavier Sastre-Garau from Institut Curie, Paris, told Reuters Health. Dr. Sastre-Garau and colleagues sought to define the HPV genotypes found in women with invasive carcinoma in France and to assess the prognostic value of the different HPV types. The most prevalent genotypes found among the 515 women with invasive cervical cancer studied were HPV 16 (55.5%) and HPV 18 (14.2%), the authors report. A minority of women (4.1%) had no HPV DNA sequences. Most women with squamous cell carcinoma had HPV 16 (59%), the report indicates, whereas more women with adenocarcinoma had HPV 18 (41%)..."
Cervical Cancer Vaccine Gains Acceptance in California
Los Angeles Times
February 18, 2009
"Despite safety concerns and the newness of Gardasil, one in four teen girls in the state received at least one dose in 2007, UCLA researchers find. The cervical cancer vaccine Gardasil is gaining widespread acceptance in California despite its newness and some controversy over its safety, UCLA researchers have found. One in four teenage girls in the state -- about 378,000 out of 1.5 million -- received at least one dose of the vaccine in 2007, its first full year of distribution, according to , released Tuesday by UCLA's Center for Health Policy Research. Among those who had not started the series of shots, a majority of teens and young adult women expressed interest in receiving the vaccine, as did their parents, the survey found..."
Prevalence of HPV Decreases Since Vaccine's Release
Independent Florida Alligator
February 10, 2009
"Fewer abnormal pap smears have been noted at the UF Student Health Care Center since Gardasil, a vaccine that prevents four forms of human papillomavirus known to cause cervical cancer, became widely used three years ago. Phylis Craig, a spokeswoman for the women's clinic at UF's Student Health Care Center, said that she gives several shots every week of the vaccine, which is marketed toward women between 9 and 26 years old..."
Most Young, Black Females Are Not Getting HPV Vaccine
HealthDay
February 4, 2009
"The human papillomavirus (HPV) vaccine, which helps cut a sexual active female's risk of cervical cancer, is viewed positively by its target audience in the black community, even though few are actually getting the shots, a new survey says. Only one in four eligible black adolescents has received the vaccine, according to a survey by the Pennsylvania Department of Public Health, which is behind funding to find ways to increase HPV vaccination rates among high-risk populations. The results of the survey were to be presented at the American Association for Cancer Research conference on the Science of Cancer Health Disparities in Carefree, Ariz..."
Getting the Gardasil Vaccine Was a Smart Choice, Teen Writes
Syracuse Post-Standard
January 11, 2009
"If you had the opportunity to save yourself from one type of cancer, would you? Although it's still relatively new, Gardasil is preventing cervical cancer and saving lives, one shot at a time. Initially, Gardasil scared me. I was the first patient in my doctor's office to be vaccinated. I knew nothing about it. The commercials and pamphlets weren't readily available. Because of my doctor's thorough explanation, I was convinced. The pain experienced from a shot is miniscule compared to cervical cancer..."
2008
Gardasil Vaccine Allergic Reactions Are Uncommon – Study
Dow Jones Newswire
December 2, 2008
"Allergic reactions to Gardasil, the humanpapilloma virus vaccine co-marketed by Merck & Co. Inc. (MRK) and Sanofi-Aventis SA (SNY), are uncommon and most schoolgirls can tolerate further doses, according to an Australian study published in the British Medical Journal Wednesday… Researchers at the Royal Children's Hospital in Melbourne, Australia, tested 25 schoolgirls with suspected allergic reactions to Gardasil after more than 380,000 vaccine doses were administered in schools. From April 2007, all young women aged 12 to 26 in Australia have received the vaccine as part of a national secondary school immunization program. Suspected allergic reactions include hives, skin rash and swelling. The researchers found that only three of the 25 schoolgirls had probable hypersensitivity to Gardasil and concluded that true hypersensitivity is uncommon. They pointed out that reactions such as hives don't increase the risk of adverse reactions in further vaccinations..."
Merck Study Shows Promise for Gardasil in Boys
Wall Street Journal Health Blog
November 13, 2008
"Merck is moving ahead with plans to extend the use of its controversial Gardasil vaccine to boys and young men. Girls may not be the only ones getting Gardasil injections for long. Scientists are reporting at a scientific meeting in Nice, France, today that 90% fewer men ages 16 to 26 years developed genital warts and other lesions after receiving Gardasil..."
Op-ed: Benefits of HPV Vaccine Outweigh Risk
Toronto Star (CAN)
November 3, 2008
"This fall the Ontario government is once again offering the Human Papillomavirus (HPV) vaccine at no cost to Grade 8 girls across the province. The goal is to vaccinate the girls during the school year against HPV, which has been identified as being the main cause of cervical cancer. As a gynaecological oncologist who treats cervical cancer patients every day, it is very encouraging to see the provincial government taking a proactive stand on this issue..."
Op-ed: Our Vote to End Cervical Cancer
Author: Lance Armstrong and John Seffrin
Washington Post
October 30, 2008
"Preventing, treating and defeating cancer are among the greatest scientific challenges and personal triumphs of our time. And right now, we have the power to save our mothers, sisters and daughters from a type of cancer that claims a life every two minutes globally..."
Letter: Is Gardasil Safe?
Washington Post
October 28, 2008
"Fretting about whether to get your daughter vaccinated against cervical cancer? Or perhaps about getting the Gardasil shots yourself? The federal government has new information that officials say should help calm fears about the safety of the shots. The analysis of data collected from about 190,000 women and girls who got at least one Gardasil shot found no evidence that the vaccine increased the risk for any serious complications, according to the Centers for Disease Control and Prevention..."
Cervical Cancer Vaccine Called Safe
Washington Post
October 22, 2008
"Gardasil, the two-year-old vaccine that's designed to prevent cervical cancer, is safe, U.S. officials said Wednesday. The U.S. Centers for Disease Control and Prevention's Immunization Safety Office said a study of 370,000 doses given to girls and young women over the past two years found no evidence that the vaccine causes an increased risk of blood clots or other serious conditions, Bloomberg News reported..."
Gardasil Passes a 2-Year Safety Check
WebMD
October 22, 2008
"Two years after Gardasil's approval, safety monitors detect no major safety problems with the HPV vaccine. Gardasil protects against infection with dangerous strains of HPV, the sexually transmitted virus that causes cervical cancer and genital warts. The CDC recommends that girls get the vaccine at age 11 or 12 years -- long before they become sexually active..."
25% of Teen Girls Vaccinated for Cervical Cancer, US Says
Los Angeles Times
October 10, 2008
"About a quarter of the nation's teenage girls received the controversial cervical cancer vaccine Gardasil last year in its first full year of distribution, federal authorities said Thursday. ‘For a new vaccine, 25% is really very good,’ Lance Rodewald, director of the division of immunization services at the Centers for Disease Control and Prevention, said in a telephone news conference releasing the data..."
Gardasil Requirement for Immigrants Stirs Backlash
Wall Street Journal online
October 1, 2008
"Even as the medical community debates the widespread use of Gardasil, a vaccine that helps prevent cervical cancer, the government has made it a mandatory treatment for young women seeking to immigrate to the U.S. The policy, which went into effect Aug. 1, has angered some immigrant advocates, who say that forcing foreigners to take the costly vaccine saddles them with an unfair financial burden. The decision has also upset health policy experts in the U.S., who see the requirement as excessive. However, even some of the CDC physicians and experts who promoted Gardasil in the U.S. say they never intended to make the vaccine mandatory for young female immigrants. 'If we had known about it, we would have said it's not a good idea,' said Jon Abramson, who was chairman of the CDC's Advisory Committee for Immunization Practices when the body recommended the vaccine for U.S. citizens last year..."
HPV Vaccine Inspires Yellow Health Journalism
Conde Nast Portfolio
July 21, 2008
"As the son of a doctor and the husband of another, I'm always on the lookout for irresponsible health journalism. And, boy, did I find some this weekend..."
U of L Study Finds HPV Vaccine May Help Prevent Other Cancers
Louisville Courier-Journal (KY)
May 16, 2008
"Some people might be able to avoid head and neck cancer if they receive a special vaccine that protects against the human papillomavirus, according to a researcher at the University of Louisville's James Graham Brown Cancer Center..."
A Dose of Reality on HPV
University Wire (Eastern Illinois U)
May 15, 2008
"Marie Smith answered a phone call in the middle of the night from her best friend. Her friend had been crying because earlier that day she was diagnosed with the human papillomavirus disease..."
Oral Cancer in Men Associated with HPV
New York Times
May 13, 2008
"The sexually transmitted virus called HPV, for human papillomavirus, is well known to lead to cervical cancer in women — which is why the federal government recommends that all girls be vaccinated for HPV at 11 or 12, before they become sexually active..."
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