Influenza - H1N1 (swine flu)
September 2009

One Swine Flu Shot For Kids Under 10 But Two Shots For Those Younger: Experts

NPR
September 21, 2009
"Children over ten will be glad to hear they will only need one vaccination shot to gain protection from the swine flu, according to the National Institute of Allergy and Infectious Diseases. Children under ten, however, aren't so fortunate. Because of their immature immune systems, they'll need two shots, according to experts. According to the NIH unit, for older children, the swine flu shot regimen will follow that of regular seasonal flu. One shot will provide a protective immune response eight to ten days after vaccination..."

Editorial: Accepting immunity

Ottawa Citizen
September 21, 2009
"With a second wave of H1N1 flu on the doorstep, Canadian public health officials face a serious stumbling block in their battle to contain the coming pandemic: the anti-vaccine movement. People who refuse to be vaccinated -- because they have misguided medical fears or because they're making a quasi-political statement against the scientific 'establishment'-- could derail progress aimed at reducing the effects of this disease, the result being that a lot of people could get seriously ill and die. Individual voices of concern about the H1N1 flu vaccine have grown into a chorus in recent weeks, and the time has come for health officials to mount a counter-offensive if they don't want to see their vaccination programs sabotaged. This needs to be done quickly..."

Distribution of Swine Flu Vaccine Will Begin in October

Washington Post
September 19, 2009
"Vaccine for the H1N1 influenza pandemic will be distributed on a three-day turnaround time from four regional warehouses around the country next month. The vaccine deliveries, expected to equal 20 million doses a week by the end of October, will be distributed among 90,000 immunization 'providers,' including health departments, hospitals, clinics, doctors' offices and pharmacies. Those were among the details unveiled Friday by the Centers for Disease Control and Prevention as part of the federal government's increasingly complex response to the pandemic of H1N1 influenza, also known as swine flu. 'This is a huge logistical process. There's not [going to be] a sudden appearance of vaccine in 90,000 refrigerators around the country,' said Jay Butler, an epidemiologist who leads the CDC's task force on the vaccine..."

Flu on Campus: What Works, What Doesn't

Reuters
September 18, 2009
"Cramped living quarters on college campuses increase students' chances of being infected with all kinds of flu, but scrupulous hand hygiene and simple face masks may help some stay healthy, at least until swine flu vaccines become available next month, health experts say. Last week, U.S. colleges and universities reported a 21 percent increase in new cases of influenza-like illness, or 6,432 cases, at 253 schools tracked by the American College Health Association. So far this academic year, there have been 13,434 reported cases of flu-like illness, most of which are presumed to be swine flu because seasonal flu has not gotten under way..."

First Doses of Swine Flu Vaccine Will Go up the Nose

NPR
September 18, 2009
"The Centers for Disease Control and Prevention says the first doses of swine flu vaccine should get into Americans in a couple of weeks -- but through their noses, not their arms..."

Swine Flu Virus Causing Confusion; It's still a mystery why H1N1 often strikes the young yet tends to be fatal in middle-aged, but not elderly, adults

Los Angeles Times
September 18, 2009
"As health officials brace for a new onslaught of illness from the novel H1N1 virus, they remain perplexed by one of the most unusual and unsettling patterns to emerge from this pandemic -- the tendency of the so-called swine flu to strike younger, healthier people. The initial explanation was that the elderly, who are usually most vulnerable to the flu, have built-in immunity as a result of their exposure more than 50 years ago to ancestors of today's pandemic strain. But the limits of the theory are becoming more clear. For starters, only a third actually have antibodies to the new H1N1..."

Australia's Swine Flu Vaccination Plan to Test Global Interest

Bloomberg
September 18, 2009
"Australia will begin immunizing people against swine flu in 12 days, heralding a global health campaign that will test public interest in the inoculation. The nationwide program will start Sept. 30 after regulators approved CSL Ltd.'s pandemic vaccine, Health Minister Nicola Roxon said today. More than 4 million doses are in major cities ready for delivery to hospitals and medical clinics next week..."

Surviving H1N1 -- with Baby in Belly

CNN
September 17, 2009
"For the past several months, Amy Wolf has been glued to the television, intently watching for information on how best to prepare for H1N1 flu. Eight months pregnant, Amy Wolf signed up for an H1N1 vaccine trial. She usually does not worry about the flu, but this year is different: Wolf is eight months into her second pregnancy. 'I watch the news like crazy, and it seems like every time I would watch or read something, there was a picture of a pregnant woman,' Wolf says. She's right to be concerned..."

US to Donate 10 Percent of Swine Flu Vaccine to WHO

Washington Post
‎September 17, 2009‎
"The United States plans to donate 10 percent of its supply of pandemic H1N1 influenza vaccine to the World Health Organization for use in low-income countries. The nation has on order 195 million doses of the swine flu vaccine, which is due to start arriving early next month. The White House said it "is taking this action in concert" with eight other countries..."

Low Levels of Key Antibodies May Lead To Severe Disease, Study Suggests

Metronews (Toronto)
September 16, 2009
"Australian researchers may have uncovered a clue as to why some people who catch swine flu suffer life-threatening illness. And if they are right, there is an existing weapon in the treatment arsenal that could help reduce the pandemic death toll. The group found that pregnant women who became severely ill with the pandemic (H1N1) 2009 virus had low levels of a particular antibody that is known to fight off viruses and help the body respond to vaccine. Moderately ill women were much less likely to have significantly suppressed levels of the antibody, the researchers reported..."

FDA Approves H1N1 Flu Vaccines

Wall Street Journal
September 15, 2009
"The Food and Drug Administration on Tuesday approved vaccines designed to protect against the H1N1 influenza virus, a key step before starting a vaccination campaign. The approval was announced by Health and Human Services Secretary Kathleen Sebelius at a hearing that was held by the House Energy and Commerce Committee. An FDA spokeswoman said the agency approved vaccines made by a unit of Sanofi-Aventis SA, Novartis AG, CSL Ltd. and AstraZeneca PLC's MedImmune unit. MedImmune makes a vaccine in the form of mist delivered through the nose rather than a shot. Ms. Sebelius said a large-scale vaccination program will begin in mid-October..."

HHS Chief: Swine Flu Vaccines Ready Soon

Washington Post
September 15, 2009
"As the administration wrestles with health-care reform, there was some good health news for a member of the team in the past few days: Help is on the way for the swine flu. Health and Human Services Secretary Kathleen Sebelius said upwards of 50 million doses of a new vaccine for the H1N1 virus will be available in mid-October, earlier than expected, with millions more doses quickly following. The initial vaccines will go to what Sebelius calls 'priority populations' -- caregivers, young people ages 6 to 24, hospital workers, pregnant women and some seniors..."

Business Not Ready for Flu, Study Says

Boston Globe
September 10, 2009
"Many American businesses are unprepared to deal with widespread employee absenteeism in the event of a swine flu outbreak, a Harvard School of Public Health study says. The survey, released yesterday, found that two-thirds of more than 1,000 businesses questioned said they could not maintain normal operations if half their workers were out for two weeks. Four-fifths expect severe problems if half are out for a month..."

Small Doctor Practices Worry about Flu Impact

Reuters
September 9, 2009
"Doctors asked the government on Wednesday to pay them more for giving vaccines and prescribing drugs on the telephone as the flu pandemic hits their communities. Meanwhile, small bankers said they should get relief from some regulatory requirements during the worst of the pandemic, as they may not have staff to fill out forms and mail out statements. The H1N1 pandemic is moderate now, and communities and governments have been planning for such a pandemic for years. But doctors, bankers and others told the House Committee on Small Business that they need some regulatory changes to handle it..."

CDC Says Most Won't Need Drugs for Flu

Washington Post
September 9, 2009
"With pandemic influenza cases on the rise across the country, federal public health authorities on Tuesday urged physicians to prescribe antiviral medicines to high-risk patients promptly but reminded the public that most people won't need, and shouldn't expect to get, the drugs if they come down with the flu. The guidance is aimed at getting optimal benefit from Tamiflu and Relenza while preventing overuse, hoarding and shortages of the drugs, as was seen briefly during the spring outbreak of swine flu. Specifically, authorities said, practitioners shouldn't wait for lab tests to confirm the presence of the novel strain of the H1N1 virus before starting antivirals in high-risk patients who show symptoms of flu..."

Blog: Preparing for a Stressful Flu Season

New York Times
September 8, 2009
"A few weekends ago, a mother I know called to ask about swine flu after her daughter complained of breathing trouble and other worrisome symptoms. Fortunately, my friend quickly reached her pediatrician, who reassured her about the child's condition. But the conversation made me realize just how stressful this flu season is going to be for parents..."

Flu Guidelines Issued for Child-Care Centers

Washington Post
September 5, 2009
"Day-care centers and other facilities responsible for young children should ensure that their employees get vaccinated against both the seasonal flu and the swine flu, federal health officials said Friday. Parents and other caregivers should also watch their children or charges closely for any signs of the flu and keep youngsters at home if they are sick during the upcoming flu season, ensuring that they do not return until at least 24 hours after their fever has gone, officials said..."

Pregnant Women Calling for Vaccine

Columbus Dispatch
September 5, 2009
"Michele Marzola said she usually skips flu shots because they make her sick. That changed this week. On Thursday, Kelsey Young, 20, died of swine flu, a week after delivering a healthy baby girl. She had become ill while pregnant. The news of Young's death, the first tied to swine flu in Franklin County and the second in Ohio involving a pregnant woman, prompted a wave of calls to area doctors' offices yesterday. Many were made by pregnant women..."

Swine Flu More Deadly to Adolescents than to Younger Children, Officials Say

Los Angeles Times
September 4, 2009
"Adolescents are at higher risk of dying from the pandemic H1N1 influenza virus than younger children, a situation that is the opposite of that encountered with seasonal flu, health authorities said Thursday. And those with underlying health problems, such as cerebral palsy, muscular dystrophy and neurodevelopmental disorders, are at the highest risk and should be among the first to be vaccinated against the new virus, according to the report in the Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report..."

One-dose Swine Vaccine Looks Promising

HealthDay News
September 3, 2009
"Hopeful news in the battle against the H1N1 swine flu emerged Thursday as European and Chinese researchers said they have developed swine flu vaccines that work with one dose, rather than two, potentially increasing the supply available for distribution. Novartis, the Swiss drug maker, found that in a British trial of 100 people between 18 and 50 years old, participants had adequate protection two weeks after just one injection, the Associated Press reported. In China, a swine flu vaccine was approved on Thursday, which also works with one dose, according to its maker, Sinovac Biotech Ltd..."

WHO Expert Says No Doubt H1N1 Vaccines Will Work

Reuters
September 2, 2009
"H1N1 vaccines should offer broad protection even if the pandemic flu virus mutates as it spreads, a top World Health Organization expert said on Wednesday. Marie-Paule Kieny, director of the WHO's vaccine research program, said that health workers should get immunized first when the shots begin to be distributed, as early as this month. 'The consensus is that the first doses will be available to governments for use in September,' she said. The U.S. Centers for Disease Control and Prevention said last week that it was unlikely the vaccines would be available before October..."

Front-Line Nurses Question How Massive Swine Flu Vaccination Plan Will Be Executed

New York Daily News
September 2, 2009
"The city is depending on public school nurses to spearhead its massive swine flu vaccination plan at elementary schools this fall. But the nurses are balking at some aspects of Mayor Bloomberg's proposal, including whether they should be the ones giving the nasal spray and shots to students. 'We have a lot of questions,' said one nurse who attended an orientation session on swine flu at Lehman College this week. But at least the city has a plan this time.'..."

Obama Urges Americans to Get H1N1 Vaccine

Reuters
September 1, 2009
"President Barack Obama urged Americans on Tuesday to get the H1N1 shot when it becomes available as the nation prepares for a second wave of swine flu as autumn approaches in the Northern Hemisphere. After a meeting with health and homeland security advisers, President Barack Obama said the United States is 'making steady process on developing a safe and effective H1N1 flu vaccine and we expect a flu shot program will begin soon. This program will be completely voluntary but it will be strongly recommended,' he said..."

Swine Flu Poses Some Challenges for Airlines; Precautions Include Removing Pillows, Blankets from Flights

USA TODAY
September 1, 2009
"Airlines say they're preparing for the return of swine flu this fall but stop short of declaring they'll bar passengers with symptoms from planes or give refunds for trips canceled because of the illness. Rather than impose special measures to deal with the H1N1 virus, several U.S. carriers emphasize they'll follow long-standing policies that permit them to keep an ill person from flying, whatever the sickness..."

New York City to Offer Students Free H1N1 Vaccines

Reuters
September 1, 2009
"All primary school-age children in New York City will be offered free vaccines for seasonal and H1N1 flu this year under a plan announced on Tuesday by Mayor Michael Bloomberg. The vaccines are part of the city's strategy to combat the new H1N1 swine flu strain that hit the city hard during the spring, infecting an estimated 750,000 to 1 million people or about 10 percent of the population..."
August 2009

Back to Flu

Boston Globe
August 31, 2009
"He's one of the nation's top flu fighters. But for Dr. Marty Cetron, the battle begins at home. That's where, like parents all across the country, he is preparing his three children - they're 9 to 15 years old - for the arrival of a fall flu season unlike any in their lifetimes. This will be the season of our dual discontent: Disease trackers expect both seasonal influenza and the novel swine strain to circulate. And swine flu, which made its US debut in the spring, has shown an unusual propensity for making the young sick while sparing the old..."

Your Doctor may Give You Swine Flu This Fall

Newsweek
August 31, 2009
"The CDC says health-care workers should be among the first in line to receive the swine-flu (H1N1) vaccine, which the government hopes will be available by mid-October. But will your doctors, nurses, and other medical providers roll up their sleeves? Only 45 percent of health-care workers get a seasonal flu shot every year..."

Poll: 2/3 in U.S. Plan to Get Swine Flu Vaccine

Reuters
August 27, 2009
"More than 90 percent of Americans plan to do something to protect themselves from the H1N1 pandemic flu virus and more than 60 percent will get vaccinated, according to an American Red Cross survey released on Thursday. Only 11 percent say they are very worried about the new swine flu and another 29 percent are somewhat worried. The rest -- 60 percent -- say they are not worried."

Experts Field Questions about Novel Flu Vaccines for Pregnant Women

CIDRAP
August 27, 2009
"Federal health officials today hosted a Web telecast to help pregnant women and new mothers prepare for an uptick in novel H1N1 flu infections, a day after a federal judge rejected an advocacy group's request to limit use of the H1N1 vaccine in pregnant women. Pregnant women in the United States and other countries have had high rates of severe infections and deaths from the novel flu virus, which prompted a federal vaccine advisory group in July to recommend that pregnant women be placed high on the priority list to receive the vaccine..."

CDC Turns to Social Sites to Get Flu Message Out

Reuters
August 27, 2009
"U.S. health authorities are turning to social networking sites such as Facebook and Twitter in a bid to prepare people to be vaccinated against the pandemic H1N1 virus. But efforts to distribute accurate information about the dangers of swine flu and the importance of vaccination are hampered by the sheer complexity of the message that the U.S. Centers for Disease Control and Prevention aims to convey. For a start, the vaccine will not be ready for widespread distribution until mid-October, after the traditional flu season has begun. The U.S. government hopes to target around 50 percent of the population for vaccination, focusing on key groups including pregnant women and healthcare workers."

E.U. Officials Lay Out Priorities for Swine Flu Vaccine

New York Times
August 26, 2009
"European Union health officials issued a list Tuesday of people who should be the first in line for vaccinations against the H1N1, or swine flu, virus. People at risk of severe disease, pregnant women and health care workers should be given priority for inoculations before the winter flu season, said the officials, who represent 27 E.U. countries and the European Commission. Prioritizing those groups is necessary because 'there will probably not be vaccine available for everyone initially, and even if there is, distribution will take time,' the officials said in a statement...In the United States, Health and Human Services Secretary Kathleen Sebelius reached a similar verdict Tuesday, saying that large-scale school closings would be ineffective in halting the spread of the virus. Instead, Ms. Sebelius said on NBC television, vaccinations would be the defense..."

Agency Urges Caution On Estimates Of Swine Flu

New York Times
August 26, 2009
"Up to 90,000 deaths from swine flu in the United States, mostly among children and young people? Up to 1.8 million people hospitalized, with 50 percent to 100 percent of the intensive-care beds in some cities filled with swine flu patients? Up to half the population infected by this winter? On Monday, a White House advisory panel issued a report with these estimates, calling them "a plausible scenario" for a second wave of infections by the new H1N1 flu. The grim numbers by the panel, the President's Council of Advisers on Science and Technology, got considerable play in the news media. On Tuesday, however, officials at the Centers for Disease Control and Prevention, the agency with the most expertise on influenza pandemics, suggested that the projections should be regarded with caution.."

Swine Flu Could Infect Half of U.S.

Washington Post
August 25, 2009
"Swine flu could infect half the U.S. population this fall and winter, hospitalizing up to 1.8 million people and causing as many as 90,000 deaths -- more than double the number that occur in an average flu season, according to an estimate from a presidential panel released Monday. The virus could cause symptoms in 60 million to 120 million people, more than half of whom might seek medical attention, the President's Council of Advisors on Science and Technology estimated in an 86-page report to the White House assessing the government's response to the first influenza pandemic in 41 years..."

CDC's Advice to Parents: Swine Flu Shots for All

Washington Post
August 25, 2009
"The first swine flu precaution that the Centers for Disease Control and Prevention suggests for parents: As soon as a vaccine is available, try to get it for everyone in your family. 'We're going to continue to stress that the vaccine is the most important thing that parents can do to protect their children,' said Tom Skinner, a CDC spokesman. This H1N1 vaccine should be taken in addition to the seasonal flu vaccine, and not as a replacement for it..."

No Side Effects So Far in Trial of Swine Flu Shot

New York Times
August 22, 2009
"There have been no serious side effects from the first set of injections of the new swine flu vaccine, federal health officials said Friday in predicting that nearly 200 million doses could be produced by year's end. Clinical trials in adults began on Aug. 7, and those in children on Wednesday..."

No Side Effects So Far in Trial of Swine Flu Shot

New York Times
August 22, 2009
"There have been no serious side effects from the first set of injections of the new swine flu vaccine, federal health officials said Friday in predicting that nearly 200 million doses could be produced by year's end. Clinical trials in adults began on Aug. 7, and those in children on Wednesday. 'There are no red flags regarding safety,' said Dr. Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases, which is overseeing the trials..."

Who Should Get Swine Flu Shots First?

TIME Magazine
August 21, 2009
"Influenza vaccinations are usually an afterthought for most people. Despite the easy availability of the shots, fewer than 40% of Americans get them in any one year — never mind that flu kills some 36,000 of us annually. But this flu season is likely to be different. Thanks to the new H1N1/09 virus, to which almost none of us are immune, flu anxiety is high — and demand for the new vaccine should be too. Washington is now gearing up to respond, hoping to inoculate millions of Americans and blunt the severity of the first pandemic in four decades..."

College Students with Flu Advised to Avoid Others

Associated Press
August 21, 2009
"Health officials are offering some basic advice for college students with flu symptoms: Avoid other people until 24 hours after a fever is gone. At colleges across the country, planning for flu season, particularly the swine flu, is well under way. Recommended safeguards could mean students with a private dorm room should stay in their rooms and find a 'flu buddy' to deliver meals and notes from class. Or it could mean students with roommates might need to move to some kind of temporary housing for sick students. And if sick students can't avoid close contact with other people, they need to wear surgical masks. The point is for sick students to isolate themselves, Education Secretary Arne Duncan said."

WHO: Save Tamiflu for the Young, Old and Pregnant

Boston Herald
August 21, 2009
"Healthy people who catch swine flu do not need antivirals like Tamiflu, but the young, the old and the pregnant surely do, the World Health Organization declared Friday in new advice to doctors. The U.N. health agency said people who are otherwise healthy with mild to moderate cases of swine flu or regular flu don't need the popular drug, calling the medical evidence for giving it to those people 'low quality.' But people thought to be at risk for complications from swine flu children less than five years old, pregnant women, people over age 65 and those with other health problems like heart disease, HIV or diabetes should definitely get the drug, WHO said..."

Study Questions U.S. Flu Vaccine Guidelines

Reuters
August 20, 2009
"Contrary to current U.S. strategy, vaccinating school children and their parents against the flu is the best way to protect the nation from influenza, including the new pandemic swine flu, U.S. researchers said on Thursday. They said vaccine priority should be given to people most likely to spread the virus, not those most at risk of serious complications from it. Seasonal and H1N1 vaccination guidelines from the U.S. Centers for Disease Control and Prevention currently target people who are likely to become the most ill if infected..."

Kids Roll Up Sleeves for H1N1 Clinical Trial

CNN
August 20, 2009
"Andrew Stein, 10, and his brother, Nathan, 7, are having a typical end-of-summer vacation: hanging out at the pool, visiting their grandparents and waiting for the beginning of school. But this week they're doing something most of their classmates will never do. The Stein brothers will be testing the new vaccine to prevent swine flu..."

H1N1 Vaccine Production Lagging Behind Expectations Limited Initial Supply Means Priority Groups Go to Front of Line for Immunizations

AAFP News
August 19, 2009
"The CDC told its Advisory Committee on Immunization Practices, or ACIP, in late July that it hoped to have 120 million doses of vaccine for the novel influenza A (H1N1) virus available by October. Manufacturing issues, however, have slowed production of the new vaccine, and federal officials now expect only about 45 million doses to be available by mid-October. According to HHS spokesman Bill Hall, 20 million more doses should be available each week thereafter..."

Austin Boy 2nd in Travis to Die of Swine Flu

Austin (Texas) American-Statesman
August 19, 2009
"A 14-year-old Austin boy has died of swine flu - the second Travis County death attributed to the novel H1N1 virus, according to Dr. Philip Huang, medical director of the Austin/Travis County Health and Human Services Department. Huang said the boy died in a San Antonio hospital, but he did not know the circumstances that led to his out-of-town hospitalization. Huang said he thought the boy had underlying health conditions that could have contributed to the death, but that was under investigation..."

Swine Flu: The Next Wave

Wall Street Journal
August 18, 2009
"With about 55 million U.S. children heading back to school in the next few weeks, concerns are growing that the H1N1 swine flu will spread even further than it already has. Identified by scientists four months ago, the virus has already turned up in nearly every corner of the world, from Argentina to Iran. It defied public-health officials' predictions of a lull in the warm summer months, proliferating in military units and children's summer camps. A volunteer receives a shot during trials of an H1N1 swine-flu vaccine last week at the University of Iowa Health Center, one of eight trial sites across the U.S. More than two million people are believed to have contracted the new flu in the U.S.; 7,511 had been hospitalized and 477 had died as of Aug. 13, according to the Centers for Disease Control and Prevention. World-wide, 177,457 people have been confirmed with the disease, and 1,462 deaths had been reported as of Aug. 12, according to the World Health Organization..."

Europe Offers Vaccinations to Contain Swine Flu

New York Times
August 18, 2009
"Anxiety over the new swine flu strain may have eased over the summer, but millions of Europeans will soon receive a sharp reminder of its virulence as governments prepare for a large-scale vaccination effort aimed at keeping a second, and possibly deadlier, wave of infections at bay..."

Report: Donovan Tests Positive for Swine Flu

ESPN
August 13, 2009
"U.S. and Los Angeles Galaxy forward Landon Donovan has tested positive for the H1N1 flu virus, SI.com reported on Thursday. Donovan, according to the report, learned of his diagnosis just a day after playing the entire 90 minutes of the U.S.'s 2-1 World Cup Qualifying loss to Mexico in Mexico City..."

Puyallup Woman Dies of Swine Flu, but First She Gives Birth

News Tribune
August 13, 2009
"A Puyallup woman who contracted swine flu while six months pregnant died Monday at Harborview Medical Center in Seattle. Katie Flyte, 27, was initially diagnosed with pneumonia, but doctors at Good Samaritan Hospital in Puyallup later discovered she had swine flu. Doctors successfully delivered the woman's child at Good Samaritan before Flyte was taken to Harborview on July 22. She died Monday, with the cause listed as acute respiratory distress, according to the King County Medical Examiner..."

Misunderstanding of 1918 Flu May Lead to Faulty Assumptions for Swine Flu: Experts

Canadian Press
August 13, 2009
"Unproven assumptions about the course of the 1918 Spanish flu pandemic may be leading to misperceptions of what the swine flu virus has in store for the world, the scientist who decoded the genetic blueprint of the 1918 virus suggests in a newly published commentary. Virologist Dr. Jeffery Taubenberger, along with co-author and medical historian Dr. David Morens, argues there is no firm evidence that the 1918 virus ratchetted up in virulence in a fall wave - because there is no solid proof outbreaks of illness in the U.S. in the spring of 1918 were caused by the same virus..."

First Flu Victim's Family Intends to Sue City

New York Times
August 11, 2009
"The wife and three sons of the first person to die during the latest swine flu outbreak in New York, an assistant principal at an intermediate school in Queens, have notified the city that they intend to file a wrongful death and negligence lawsuit against the city. Bonnie Wiener, the widow of the flu victim, Mitchell Wiener, and their three sons, Adam, Jordan and Farrell, served a 'notice of claim' to the city on Aug. 5, charging that the city had failed to react quickly enough to the swine flu outbreak at Intermediate School 238 in Hollis, Queens, where Mr. Wiener worked..."

Costa Rica's President Has Swine Flu: Oscar Arias is being treated and quarantined at home

MSNBC
August 11, 2009
"Nobel Peace laureate and Costa Rican President Oscar Arias said Tuesday that he has swine flu, showing that not even a head of state is safe from the virus that has caused worldwide concern but relatively few deaths. The 69-year-old president and Nobel Peace Prize winner said in a statement that he was quarantined at home and is being treated with the anti-flu medicine oseltamivir..."

WHO: Pandemic Flu Spreading with Asian Monsoon Season

Reuters
August 11, 2009
"H1N1 pandemic flu is spreading in India, Thailand and Vietnam with the onset of Asia's monsoon season, the World Health Organisation (WHO) said on Tuesday. But transmission of the new virus appears to have peaked in parts of the southern hemisphere including Argentina, Chile, Australia and New Zealand, the United Nations agency said..."

Obama Strikes Note of Unity at Mexico Summit

Christian Science Monitor
August 10, 2009
"At the North American Leaders Summit in Mexico today, the three heads of state reiterated their commitment to the pressing issues of the day, including security, economic recovery, climate change, and the mitigation of swine flu..."

Canada Dismisses Warning about Flu Drug

Globe and Mail
August 10, 2009
"Canadian health authorities will not change their practice of prescribing the anti-viral drug Tamiflu to treat cases of pandemic H1N1 flu in children, despite a new study that raises questions about the drug's effectiveness. Researchers at the University of Oxford cautioned about the broad use of anti-viral drugs to treat children 12 years of age and younger suffering from seasonal flu. They found anti-viral drugs have little or no effect on asthma flare-ups, ear infections or bacterial infections in children. Tamiflu was also linked to increased vomiting..."

School Nurses in Short Supply

USA Today
August 10, 2009
"If swine flu reappears in schools this fall, it'll probably be a school nurse who first discovers it. But nationwide, the ratio of nurses to students falls short of the federally recommended standard, raising concerns that the shortage could undermine efforts to catch and control what could be a deadly flu season. A USA TODAY analysis of Census data from 2005 to 2007 suggests that each school nurse cares, on average, for 971 students..."

Swine Flu Vaccine Trials Begin Testing Volunteers

NPR
August 10, 2009
"As a part of preparing for a major outbreak of the H1N1 swine flu this fall and winter, the government began testing H1N1 influenza vaccine Monday. The first clinical trials are enrolling up to 2,400 people and will test H1N1 vaccine made by two drug companies using the so-called seed stock of the H1N1 virus provided by the federal government. The trials are designed to determine if the vaccine is safe in healthy people of various ages and gauge how many doses are needed to protect against the swine flu. The testing is taking place at multiple Vaccine and Treatment Evaluation Units across the country — the longstanding vaccine clinical trials infrastructure run by National Institute of Allergy and Infectious Disease. The first trials are testing healthy adult volunteers between the ages of 18 and 65. If the first eight days of adult testing don't raise any safety concerns, researchers will begin testing the vaccine in healthy children ages 6 months to 18 years..."

The Doctor's World: Seeking lessons in swine flu fight

New York Times
August 10, 2009
"As the three-month-old outbreak of swine flu raises havoc during the winter season in the Southern Hemisphere, officials in the United States are carefully seeking clues from there to deal with its likely return in this country in the fall, before a vaccine can protect large numbers of people..."

51 US Soldiers in Iraq Diagnosed with Swine Flu; Iraqi Health Officials Confirm Country's First H1N1 Death

MSNBC News
August 9, 2009
"Fifty-one American troops in Iraq have been diagnosed with and treated for swine flu, while another 71 soldiers remain in isolation suspected of contracting the potentially deadly virus, the U.S. military said Sunday. The figures were released as Iraqi health officials confirmed Sunday the country's first swine flu death. A woman in the southern holy Shiite city of Najaf died of the disease, raising fears about a possible outbreak among worshippers making pilgrimages to the revered sites. All the 51 U.S. troops diagnosed with the flu have fully recovered, while the 71 suspect cases are in isolation, said Col. Michael D. Eisenhauer, the chief of clinical operations in Iraq..."

Swine Flu Should Not Close Most Schools, Federal Officials Say

New York Times
August 7, 2009
"Most schools should be able to stay open even if swine flu outbreaks occur again this fall, government officials said Friday as they issued recommendations for dealing with the illness when the school year starts. Decisions about whether to close schools should be made locally, the officials said, and ‘should balance the goal of reducing the number of people who become seriously ill or die from influenza with the goal of minimizing social disruption and safety risks to children,' which sometimes occur when schools close..."

Quick Tests for the Flu Found Often Inaccurate

New York Times
August 6, 2009

"As the swine flu spreads, many doctors and hospitals are turning to rapid tests that can determine within minutes whether an anxious patient has the flu. Sales of such tests are soaring. But the tests have a severe limitation: They may fail more than half the time to detect swine flu infections, according to newly published studies and to experts in medical testing..."

WHO: Fast -Track Flu Vaccines Don't Reduce Safety

New York Times
August 6, 2009
"Procedures to fast-track approvals of new vaccines to combat H1N1 influenza do not reduce safety, the World Health Organization said on Thursday. The WHO said vaccines had to be available quickly and in large quantities to have the greatest impact..."

Big Drug Makers Start Trials of Swine Flu Vaccines

Reuters
August 5, 2009
"Novartis has started human testing of H1N1 swine flu vaccine candidates while Sanofi-Aventis, the world leader in flu shots, will commence within days, company officials said on Tuesday. The launch of clinical trials is a key part of a widening program of work being undertaken by big pharmaceutical companies as they prepare for mass vaccination from next month. GlaxoSmithKline, the other 'big three' flu vaccine supplier, said it would initiate clinical studies later this month..."

Pneumonia Vaccine May Help Limit Swine Flu Deaths

Los Angeles Times
August 4, 2009
"In years past, the nation's attempts to prevent flu-related deaths have focused on limiting transmission of the virus through widespread vaccination programs. This year, with school starting up well before a vaccine for the pandemic H1N1 influenza virus will be available, there will be little that can slow the spread of the virus for the next few months. But there may yet be something that can be done to reduce hospitalizations and deaths associated with the virus, commonly known as swine flu, public health..."

Schools Prep for Spread of Swine Flu

USA Today
August 3, 2009
"As the first day of classes approaches for some districts, school and health officials in several states are preparing for the possibility of wider outbreaks of the H1N1 virus. Swine flu, which disproportionately targets teenagers and young adults, is expected to begin spreading more rapidly when students return to the close quarters of classrooms and dormitories, county and state health officials say. They expect greater-than-usual numbers of students to seek inoculations because of widespread publicity about H1N1..."

Opinion: Prepare for a Vaccine Controversy
By Arthur Allen

New York Times
August 2, 2009
"A few years ago public health officials set up a time share in Pennsylvania hens. Under contracts signed with several farmers, the hens continued to lay for their regular customers until the moment this past spring when the federal government requisitioned their eggs to grow flu vaccine. Strategic hen reserves are part of a success story: the government's readiness for the current H1N1 flu pandemic. Public health officials had already stockpiled millions of doses of antiviral drugs, created diagnostic kits that detected the virus as soon as it appeared in California in April and enrolled five companies to make vaccine..."

Opinion: Fly the Germ-Free Skies
By Mark Gendreau, MD

New York Times
August 2, 2009
"The new H1N1 flu has already been transmitted from one passenger to another on a commercial airline, and it is likely that more such incidents will occur if the virus resurges as anticipated this fall. The aviation industry and the Centers for Disease Control and Prevention have tried to reassure passengers that air travel is still safe, but so far they have done too little to try to limit the number of such transmissions..."

Mothers-to-be Urged to Consider Swine Flu Vaccinations

Chicago Tribune
August 2, 2009
"With pregnant women facing a high risk of death from swine flu, health officials in Illinois are planning an aggressive campaign to educate doctors and encourage expectant mothers to get vaccinated against the virus, which threatens to spread rapidly this fall. 'In general, when people are pregnant, they are reluctant to take medication they fear might cause harm to the child,' said Dr. Julie Morita, medical director for the immunization program at the Chicago Department of Public Health. 'But if their physician says 'I think you need a flu vaccine,' they are more likely to heed it.'..."
July 2009

CDC to Seek Public's Advice on H1N1 Vaccination Drive

CIDRAP
July 31, 2009
"The Centers for Disease Control and Prevention (CDC) plans to gather the public's thoughts in August on how big this fall's H1N1 influenza vaccination drive should be. The CDC will hold 10 'public engagement' meetings around the country to get the citizenry's advice on whether the vaccination program should be an all-out effort or something more modest, according to Roger Bernier, PhD, MPH, senior advisor in the CDC's National Center for Immunization and Respiratory Diseases. The agency wants to take the public pulse on the issue because there's so much uncertainty about the scale and of the severity of the pandemic and the demand for the vaccine this fall and winter, Bernier said..."

Vaccine Plan in U.S. May Endanger Supply, Lancet Says

Bloomberg News
July 31, 2009
"U.S. plan to rely on swine flu vaccines without ingredients to stretch the supply would reduce the number of available shots just when other countries need them most, the British journal Lancet said in an editorial. The ingredients, called adjuvants, have never been approved for flu vaccines in the U.S. and are controversial because some studies show they cause immune disorders in mice..."

Nasal Vaccine Holds Promise Against Swine Flu

New York Times
July 30, 2009
"As the nation girds for a possible swine flu pandemic, one of the big weapons may come from an unexpected source - a vaccine squirted or dropped into the nose. MedImmune, which already makes the nasal spray vaccine FluMist for seasonal flu viruses, says it is on track to produce about five times as much swine flu vaccine as it had expected - so much, in fact, that it will run out of nasal spray devices and is looking to administer the vaccines with droppers instead..."

Flu Vaccine Panel Creates Priority List

Washington Post
July 30, 2009
"A complicated list of who should get pandemic flu vaccine in the fall is now set. When the vaccine starts arriving in September, first in line will be pregnant women; the caretakers of infants; children and young adults; older people with chronic illness; and health-care workers. That's the advice of a 15-member committee of experts, which met all day Wednesday at the Centers for Disease Control and Prevention in Atlanta to advise the federal government on vaccine policy..."

Wal-Mart Weighs Role in U.S. H1N1 Vaccination Plans

Reuters
July 30, 2009
"Wal-Mart Stores Inc is discussing with U.S. health officials the possibility of putting vaccination sites at some of its stores for an H1N1 swine flu inoculation campaign this fall, a company official said on Thursday. Federal officials met with Wal-Mart executives on Wednesday in Arkansas to discuss the issue, Dr. John Agwunobi, president of health and wellness for Wal-Mart U.S., told public health leaders at a conference in Orlando..."

Volunteers Swarm for Shot at Swine Flu Vaccine

MSNBC

July 29, 2009
"It's been just a week since Monica Hankins first heard scientists were looking for volunteers to test an experimental vaccine to prevent the H1N1 swine flu, but the Festus, Mo., mom and her family already are signed up. She wants her two young daughters, Isabella, 3, and Maya, 19 months, to be among the first to be protected against the previously unknown virus that has launched a global pandemic and claimed more than 800 lives worldwide, including more than 300 in the United States..."

Federal Panel Issues H1N1 Vaccine Guidelines

CNN
July 29, 2009
“A federal advisory committee issued sweeping guidelines Wednesday for a vaccination campaign against the pandemic swine flu strain, identifying more than half the U.S. population as targets for the first round of vaccinations. The advisory panel's guidelines don't trigger the start of vaccinations but are usually accepted by the government. The priority groups include pregnant women; health care and emergency services personnel; children, adolescents and young adults up to age 24; household and caregiver contacts of children younger than six months; and healthy adults with certain medical conditions..."

CDC Says Pregnant Women with Flu Symptoms Should Receive Anti-Viral Drugs

Wall Street Journal
July 29, 2009
“The Centers for Disease Control and Prevention said Wednesday pregnant women suspected of having the flu should be promptly treated with antiviral medications. The CDC, in a study set to be published in the medical journal Lancet, said pregnant women are more severely impacted by the H1N1 virus. CDC said pregnant women had higher rates of hospitalization and a greater risk of death compared to the general population...“

EU Panel to Review H1N1 Vaccines Before Flu Season

Wall Street Journal
July 24, 2009
“The European Medicines Agency said Friday it has started to receive data on H1N1 pandemic vaccines following the review beginning in July, with the commitment from the Committee for Medicinal Products for Human Use, to fast-track the review of data as vaccine manufacturers make them available.... “

In Trials for H1N1 Vaccine, Dosage Is Key

USA Today
July 23, 2009
“The race to test a new pandemic flu vaccine is poised to begin, starting with trials in healthy adults and then, if no safety questions emerge, in children, federal officials said Wednesday. The goal is to produce enough vaccine to protect at least 120 million people against an entirely new flu virus, H1N1, also known as swine flu, before flu season takes off in the fall... “

Think H1N1 Is Bad Now? Wait Till Flu Season

TIME
July 22, 2009
“When the World Health Organization announced on July 16 that it would stop issuing global counts of confirmed cases of the H1N1/09 virus (the new WHO-approved name differentiates the virus from older versions of H1N1), it wasn't because the disease had burned out. Far from it...“

First Vaccine for Foiling Swine Flu to be Tested

Bloomberg News
July 22, 2009
“The first human trials of a swine- flu vaccine are set to begin in Australia as deaths and infections from the H1N1 virus mount worldwide, intensifying demand for a protective shot. CSL Ltd., the only flu-vaccine maker in the Southern Hemisphere, plans to start the research tomorrow in Adelaide by injecting a group of healthy volunteers with its experimental vaccine, the company said last week...“

H1N1 Vaccine on the Way for Fall Distribution

American Medical News
July 20, 2009
“Physicians and other health care professionals likely will be among the first to receive a new influenza A(H1N1) vaccine, which should be ready by mid-October, said Dept. of Health and Human Services Secretary Kathleen Sebelius. She made the announcement at a summit of local, state and federal health and school officials held July 9 at the National Institutes of Health...“

CDC expects to have enough H1N1 vaccine

UPI
July 18, 2009
“Physicians and other health care professionals likely will be among the first to receive a new influenza A(H1N1) vaccine, which should be ready by mid-October, said Dept. of Health and Human Services Secretary Kathleen Sebelius. She made the announcement at a summit of local, state and federal health and school officials held July 9 at the National Institutes of Health...“

Swine Flu Expected to Return with Opening of School

New York TImes
July 17, 2009
“Physicians and other health care professionals likely will be among the first to receive a new influenza A(H1N1) vaccine, which should be ready by mid-October, said Dept. of Health and Human Services Secretary Kathleen Sebelius. She made the announcement at a summit of local, state and federal health and school officials held July 9 at the National Institutes of Health...“

Year-End Release Likely for Flu Vaccine

Boston Globe
July 14, 2009
"A fully licensed swine flu vaccine might not be available until the end of the year, a top official at the World Health Organization said yesterday, in a report that could affect many countries' vaccination plans. But countries could use emergency provisions to get the vaccines out quicker if they decide their populations need them, said Marie-Paule Kieny, director of WHO's Initiative for Vaccine Research, during a news conference. The swine flu viruses being used to develop a vaccine aren't producing enough of the ingredient needed for the vaccine, and WHO has asked its laboratory network to produce a new set of viruses as soon as possible..."

Study: Deadly 1918 Pandemic Took Years to Evolve, Through Pigs, Offering Lessons for Today

Chicago Tribune
July 13, 2009
"History's deadliest flu pandemic, in 1918, may not have made a sudden jump from birds to people after all. New research says the pig played a big role as an influenza mixing bowl - a gene probe with lessons for tracking today's swine flu outbreak. The genetic ancestor hunt shows pieces of the 1918 killer virus were quietly circulating in people and pigs up to 15 years before the pandemic erupted, researchers reported Monday..."

WHO Says Health Workers Priority for H1N1 Vaccine

Reuters
July 13, 2009
"Healthcare workers should get priority access to H1N1 flu vaccinations to ensure health systems keep functioning as the swine flu pandemic spreads around the globe, the World Health Organization said on Monday. Marie-Paule Kieny, WHO director of the Initiative for Vaccine Research, said the agency's experts had concluded every country in the world would need access to vaccines, which drug companies are now racing to produce. Disappointingly, Kieny said, yields from growing the new virus in chicken eggs -- the mainstay of flu vaccine production -- had so far been 'poor,' at only 25 to 50 percent of that achieved with normal seasonal flu strains. Alternative strains are now being studied that will hopefully increase output, she added..."

Swine Flu Vaccine Trials in Rochester

WHAM (NY)
July 13, 2009
"Clinical trials for a swine flu vaccine will begin in just a few weeks in Rochester. 'We run trials for the pharmaceuticals industry,' said Dr. Matthew Davis. Rochester Clinical Research is the place where vaccines earn their stripes -- passing test after test before being passed on to the public..."

H1N1 Stunned Emory Doctors: Medical team that saved Kentucky woman recalls swift severity of illness

Atlanta Journal-Constitution

July 10, 2009

"The Kentucky woman was having a grand vacation that included a Mexican getaway, shopping in Atlanta and a wedding in LaGrange. But on May 7, she found herself on an emergency helicopter flying to Emory University Hospital --- near death. Having spent about two weeks in a LaGrange hospital, the 31-year-old woman's already serious case of swine flu had, within a matter of hours, taken a terrible turn for the worse. She was in respiratory failure, meaning she could no longer breathe on her own, and doctors had discovered a blood clot in her lungs. So the LaGrange doctors rushed her to Emory, with its infectious disease specialists and advanced equipment. The woman's identity has not been made public, at her request, but this week eight of the Emory doctors and staff recounted their monthlong struggle to save her..."

U.S. Ready to Spend Billions on Flu Vaccine

Boston Globe
July 10, 2009
"The Obama administration said yesterday that it has billions of dollars available to help pay for a national H1N1 flu vaccine program that could be ready starting in mid-October. Health and Human Services Secretary Kathleen Sebelius made the announcement at an all-day summit on the outbreak of what is more commonly known as swine flu. One purpose of the gathering, officials have said, is to help restore a sense of urgency to the worldwide response to the epidemic..."

15 Air Force Academy Cadets Have Swine Flu

Denver Post
July 10, 2009
The Academy announced the confirmed cases in Colorado's largest outbreak of the H1N1 virus. The Academy announced Thursday that 89 cadets were isolated with flu-like symptoms. Academy spokeswoman Capt. Corinna Jones says that most of the sick cadets are "doolies," members of the incoming freshman class who began training June 25. The cadets began coughing and showing other upper respiratory symptoms last Monday..."

Obama Warns of Return of Swine Flu in Fall

New York Times
July 10, 2009
"The Obama administration warned Americans on Thursday to be ready for an aggressive return of the swine flu virus in the fall, announcing plans to begin vaccinations in October and offering states and hospitals money to help them prepare. The potential for a significant outbreak in the fall is looming," President Obama said by telephone link from Italy to the White House's H1N1 Influenza Preparedness Summit, held at the National Institutes of Health..."

Students 1st in Line for Flu Vaccine

Washington Post
July 10, 2009
"School-age children will be a key target population for a pandemic flu vaccine in the fall, and they may be vaccinated at school in a mass campaign not seen since the polio epidemics of the 1950s. The federal government should get about 100 million doses of vaccine by mid-October, if the current production by five companies goes as planned. But enough vaccine for wide use by the 120 million people especially vulnerable to the newly emerged strain of H1N1 influenza virus will not be available until later in the fall..."

U.S. Government to Fully Fund Swine Flu Vaccines

Reuters
July 9, 2009
"The U.S. government will fully pay for any autumn vaccination program against the new H1N1 swine flu, Health and Human Services Secretary Kathleen Sebelius said on Thursday. Although it is not certain Americans will be offered the vaccine, Sebelius said plans were on track for a mid-October vaccination program. 'We have already appropriated about a billion dollars to buy the bulk ingredients,' Sebelius told a swine flu 'summit' of state and local leaders at the National Institutes of Health. She said another $7.5 billion was available from emergency preparedness funds..."

San Quentin Limits Intake of Prisoners

San FranciscoChronicle
July 9. 2009
"Seeking to prevent an outbreak of swine flu from spreading beyond prison walls, officials at San Quentin State Prison on Wednesday stopped accepting prisoners from 16 Northern California counties, including all nine in the Bay Area. The move follows by two..."

H1N1 Vaccine Trials Happening In North Texas

CBS 11 (TX)
July 8, 2009
"It is a mystery the World Health Organization is trying to solve. How did a handful of H1N1, or swine flu, cases balloon into a global pandemic in less than two months? The organization says there are 77,000 confirmed cases and 332 deaths worldwide, but U.S. health officials say as many as one million Americans have been infected with H1N1. With concerns among health officials that the virus will make a strong comeback this fall, North Texas could be on the front line for a vaccine. Five-year-old Grace Schmidt and her two-year-old brother, Matthew, will be among the first to test the swine flu vaccine next month..."

UN Chief Says $1 Billion May Be Needed for Antivirals, Vaccines Against Swine Flu This Year

Associated Press (LA Times)
July 6, 2009
"U.N. Secretary-General Ban Ki-moon says the world body may need over $1 billion to fight the swine flu pandemic for the rest of this year. Ban says funds have not come in as expected. He says the money is needed to ensure the poorest countries get vaccine supplies and antivirals if the pandemic continues to spread. Ban told reporters in Geneva on Monday that the relative mildness of the pandemic so far should not be taken for granted. He says the swine flu outbreak is a worldwide problem that needs global solidarity. The World Health Organization says 429 people died of swine flu and over 94,000 have been infected. Experts fear the number of infected people may be much higher than those confirmed..."

Journal Was Told of Flu Mutation First

Japan Times
July 6, 2009
"The Osaka Prefectural Government sent a research paper to a U.S. medical journal on the 1st case in Japan of a genetic mutation of swine flu resistant to Tamiflu about a week before making the finding public, officials said Sunday. 'It's not that we intentionally placed priority on the manuscript and delayed the announcement,' said Tatsuya Oshita, an official in the prefectural government's health and medical care department. 'As it turned out, we dealt with the matter in a way that could be criticized, and we are sorry.' The H1N1 virus resistant to Tamiflu was found in a woman in her 40s in Osaka Prefecture on 18 Jun 2009 -- 2 weeks before the announcement -- through virus sample analysis at the Osaka Prefectural Institute of Public Health, the officials said..."

Tamiflu Resistant H1N1 from Hong Kong More Worrying than Earlier Findings Canadian Press

July 4, 2009
"All cases of Tamiflu resistance are not created equal. So while the 1st 3 instances of swine flu infection with Tamiflu-resistant viruses were reported in the past week, it was Number 3, not Number 1 that put influenza experts on edge. Public health authorities in Hong Kong announced Friday [3 Jul 2009] they have found a case of Tamiflu resistance in a woman who hadn't taken the drug. That means she was infected with swine flu viruses that were already resistant to Tamiflu, the main weapon in most countries' and companies' pandemic drug arsenals..."

Swine Flu Death Toll in Argentina Climbs

New York Times
July 4, 2009
"The death toll from swine flu in Argentina continued to rise as President Cristina Fernandez de Kirchner said she would not rule out closing major public venues where the virus could spread more quickly. Dr. Juan Manzur, the new health minister, said Friday that 44 people had died from swine flu and that the country had 2,800 confirmed flu cases. The numbers reflected a sharp increase compared with a week earlier, when there were 26 deaths and 1,587 cases. Swine flu has killed more people in Argentina than in any other country in South America, where the winter flu season is just beginning..."

Studies: Novel H1N1 Affects Deep Lung Tissue, Transmits Fairly Well

July 2, 2009
CIDRAP News
"The novel H1N1 (swine) influenza now circling the globe causes more serious lung disease than seasonal flu strains and sheds from the lung and throat tissue where it reproduces at higher rates, according to two animal studies published today—findings that could explain autopsies and case reports of severe pneumonia as well as the virus's rapid spread. And while the studies, conducted in ferrets and mice, agree that the new flu passes fairly well between individuals, they disagree over the effectiveness of different modes of transmission..."

Invest in Vaccines to Avert Pandemic

Atlanta Journal-Constitution
July 1, 2009
"Last month, the World Health Organization finally declared that the new H1N1 virus has become pandemic. Monday it reported a big jump in cases and fatalities since last week. How many people this virus will sicken and kill depends, ultimately, on three things: the virus itself; the impact of what are known as “non-pharmaceutical interventions,” or NPIs; and the availability and effectiveness of a vaccine. The virus will be the most important factor. Influenza is one of the fastest-mutating organisms in existence, which makes it unpredictable, and a virus newly infecting the human population is likely to be even more unpredictable as it adapts to a new environment..."
June 2009

Swine Flu 'Shows Drug Resistance'

BBC News
June 29, 2009
"Experts have reported the 1st case of swine flu that is resistant to Tamiflu, the main drug being used to fight the pandemic. Roche Holding AG confirmed a patient with H1N1 influenza in Denmark showed resistance to the antiviral drug. David Reddy, company executive, said it was not unexpected given that common seasonal flu could do the same..."

Study Shows Swine Flu's Spread Can Be Tracked Through Air Travel

Chicago Tribune
June 29, 2009
"In a startling measure of just how widely a new disease can spread, researchers accurately plotted swine flu's course around the world by tracking air travel from Mexico. The research was based on an analysis of flight data from March and April last year, which showed more than 2 million people flew from Mexico to more than 1,000 cities worldwide. Researchers said patterns of departures from Mexico in those months varies little from year to year; swine flu began its spread in March and April this year..."

U.S. Cases of New Flu Hit a High This Week

Wall Street Journal
June 29, 2009
“The new H1N1 swine flu may cause more-severe illness than similar seasonal strains but may spread less easily, according to preliminary findings from a study of ferrets to be published soon by Centers for Disease Control and Prevention scientists. CDC officials said Friday they received reports of nearly 6,300 new U.S. cases in the past week, more than in any other week since the outbreak began in late April, signaling the virus isn't letting up despite summer's arrival. Almost all flu cases now tested are the new H1N1 flu rather than regular seasonal flu, the agency said. U.S. government officials and manufacturers are preparing to produce 600 million doses of vaccine for the H1N1 virus, an effort that would dwarf seasonal-flu campaigns and would include enough for those vaccinated to receive two doses. As many as 60 million doses could be ready by September, they said at a meeting Friday of the Advisory Committee on Immunization Practices. But federal officials haven't decided whether to go ahead definitively with the campaign, determined who would get vaccinated, or worked out logistics for carrying out a campaign alongside seasonal-flu vaccinations...”

Swine Flu Halts Muscular Dystrophy Camps

Philadelphia Inquirer
June 25, 2009
"Thousands of Jerry's Kids will not attend camps this summer after officials halted the program in the face of 17 suspected swine-flu cases among campers, including six in Montgomery County. The cancellation, which came after about 1,800 attended 33 camps, affects 2,500 children scheduled to attend 47 other camps. The children's hereditary muscle weakness and compromised immune systems leave them vulnerable to the H1N1 strain of influenza, Muscular Dystrophy Association officials said..."

In New Theory, Swine Flu Started in Asia, Not Mexico

New York Times
June 23, 2009
"Contrary to the popular assumption that the new swine flu pandemic arose on factory farms in Mexico, federal agriculture officials now believe that it most likely emerged in pigs in Asia, but then traveled to North America in a human. But they emphasized that there was no way to prove their theory and only sketchy data underpinning it. There is no evidence that this new virus, which combines Eurasian and North American genes, has ever circulated in North American pigs, while there is tantalizing evidence that a closely related 'sister virus' has circulated in Asia. American breeding pigs, possibly carrying North American swine flu, are frequently exported to Asia, where the flu could have combined with Asian strains. But because of disease quarantines that make it hard to import Asian pigs, experts said, it is unlikely that a pig brought the new strain back West. 'The most likely scenario is that it came over in the mammalian species that moves most freely around the world,' said Dr. Amy L. Vincent, a swine flu specialist at the Agriculture Department's laboratory in Ames, Iowa, referring, of course, to people. But a sample taken from a pig in Hong Kong in 2004 was recently found to have a virus nearly matching the new flu. That flu, which had seven of the new flu's eight genome sequences, was noted in an article in Nature magazine on June 11, which called it a 'sister virus.'..."

State's Only Swine Flu Death still a Mystery
Specialists Hunting for Clues to Explain Woman's Decline

Boston Globe
June 23, 2009
"The only person known to have died of swine flu in Massachusetts suffered from none of the underlying medical conditions that can turn a relatively mild viral infection into a life-threatening illness, city disease trackers disclosed yesterday. The finding deepens the mystery around the June 14 death of a 30-year-old Boston woman who arrived at Boston Medical Center already gravely ill from symptoms associated with the respiratory disease, known by the scientific designation H1N1. Investigators with the Boston Public Health Commission delved through medical records obtained from the woman's primary care physician, hunting for clues that might explain her precipitous decline. But there was no evidence she had ever been diagnosed with asthma, cancer, diabetes, heart disease, or any other chronic malady known to intensify the risk of dying from a flu virus..."

No Signs of H1N1 Flu in Babies at NC Hospital

News & Observer (NC)
June 18, 2009
"Officials say seven of the 33 babies who may have been exposed to H1N1 swine flu have been sent home from a North Carolina hospital and that none show flu symptoms. The News & Record of Greensboro reported Tuesday that a respiratory therapist who unknowingly exposed the babies at The Women's Hospital tested positive for the virus last week. The babies are in the hospital's neonatal intensive care unit. Hospital officials are asking anyone with flu-like symptoms to stay at home away from others, drink fluids and use over-the-counter medicine to treat their symptoms..."

Editorial: Pandemic Reality Check

Washington Post
June 23, 2009
"This month, the World Health Organization finally declared that the new H1N1 virus has become pandemic.Yesterday it reported a big jump in cases and fatalities since Friday. How many people this virus will sicken and kill depends, ultimately, on three things: the virus itself; the impact of what are known as 'non-pharmaceutical interventions,' or NPIs; and the availability and effectiveness of a vaccine. The virus will be the most important factor. Influenza is one of the fastest-mutating organisms in existence, which makes it unpredictable, and a virus newly infecting the human population is likely to be even more unpredictable as it adapts to a new environment...But we do have non-pharmaceutical interventions and the possibility of a vaccine. Such interventions would come into play primarily in a moderate or severe pandemic..."

Editorial: A Pandemic's Dry Run

Boston Globe
June 21, 2009
"Although Massachusetts recorded its first swine-flu death this month, the effect of the disease has not been as dire as many feared. As a result, public health officials have been able to view the health system's response to the pandemic as a test case for an even more dangerous outbreak of flu. Among the lessons learned is the need for better coordination between the public-health sector and the private suppliers of the tools needed to contend with flu: face masks, swabs, and antiviral medicines such as Tamiflu..."

Experts See Bad, but not Disastrous, Flu Season

Wall Street Journal
June 19, 2009
"So what are health officials doing to help us prepare for the upcoming flu season? According to the U.S. Department of Health and Human Services, which also oversees the Centers for Disease Control and the Food and Drug Administration, the government has now shifted its pandemic planning focus from H5N1 to H1N1 for the upcoming flu season. Seasonal flu still remains a priority. The government is still asking the five U.S.-licensed flu vaccine makers to supply the U.S. market with about 100 million doses of seasonal flu vaccine, a request on par with those of recent years..."

Camps Seeing Outbreaks of Swine Flu, Agency Says

New York Times
June 19, 2009
"Although it is fading in much of the nation as warmer weather comes on, swine flu is causing outbreaks in summer camps just as it has in schools, federal officials said Thursday. The advice to camp administrators and parents is basically the same as for schools, said Dr. Daniel B. Jernigan, deputy director of the flu division of the Centers for Disease Control and Prevention: Camps should be on the alert for sick children, who should be kept home for a week or until 24 hours after symptoms have finished. (Not all camps offer refunds, the American Camp Association noted.) Parents should be prepared to take sick children home on short notice. Religious camps in Clayton, Ga.; Santa Rosa, Calif.; and Cleveland, Ga., and a Boy Scout camp near Asheville, N.C., all reported probable swine flu cases in local newspapers this week..."

Editorial: Death from the Flu

Milwaukee Journal Sentinel
June 19, 2009
"The swine flu pandemic passed another tragic milestone in Wisconsin this week with the first deaths of youths from the disease. Health officials and family members said 14-year-old Tiara Mosely of Milwaukee did not appear to have any of the underlying medical conditions that put those who contract the disease at high risk...."

Malaysia Introduces Stricter Measures to Fight A/H1N1 Flu

English News Service
June 19, 2009
"Malaysia has introduced ten new measures to prevent A/H1N1 flu from spreading in the country. Malaysian Deputy Prime Minister Muhyiddin Yassin said that one of the measures was compulsory health declaration form by all travelers arriving in the country, which would be gazetted next week, according to local newspapers on Friday. Any travelers whoever fail to do so could be liable to a 10,000 ringgit (2,857. 1 U. S. dollars) fine or two years' jail or both, under the Malaysian Disease Prevention Act, Muhyiddin told reporters here on Thursday. Other measures included sending health officers on board flights to scan body temperatures of passengers coming from the United States, Melbourne of Australia and Manila of the Philippines..."

H1N1 Cases in Health Workers Show Need for Protection

CIDRAP News
June 18, 2009
"An analysis of novel H1N1 influenza cases in healthcare workers in the early weeks of the epidemic shows that half of them were probably infected on the job, and most of those weren't using respiratory protection, the Centers for Disease Control and Prevention (CDC) said today. Among 26 cases for which detailed information was available, 13 of the healthcare personnel (HCP) were believed to have been infected in a healthcare setting, the CDC said. Only three of the infected workers reported using a surgical mask or an N-95 respirator. The findings suggest that health workers are being infected both at work and in the community and that healthcare facilities need to reinforce messages about current infection control recommendations, the CDC said in the Jun 19 issue of Morbidity and Mortality Weekly Report..."

Vaccinate Kids to Control H1N1 Flu

Reuters
June 18, 2009
"Targeting children for vaccination may be the best way of using limited supplies of vaccine to control the current H1N1 flu pandemic, British researchers said on Thursday. Drugmakers are racing to make a vaccine against the new flu strain but if the disease increases significantly in the northern hemisphere autumn, as many experts fear, there are unlikely to be enough shots to vaccinate entire populations. Researchers from the University of Warwick said that vaccinating children rather than adults would not only help protect a group at greatest risk of exposure to the virus, but would also offer protection to unvaccinated adults..."

Sebelius Says Kids May Get Swine Flu Shots First

Washington Post
June 16, 2009
"Schoolchildren could be first in line for swine flu vaccine this fall - and schools are being put on notice that they might even be turned into shot clinics. Health and Human Services Secretary Kathleen Sebelius said Tuesday she is urging school superintendents around the country to spend the summer preparing for that possibility, if the government goes ahead with mass vaccinations..."

Flu Pandemic Spurs Queries about Vaccine

Wall Street Journal
June 15, 2009
"Governments and drug companies ramping up production of a vaccine against the swine-flu virus are facing a tough question: Who really needs it? The world's biggest drug companies have started producing vaccines against the H1N1 virus and expect the first doses to be available by the fall. Many Western countries have ordered millions of doses, at a cost of more than $1 billion. But they have yet to figure out who should be first in line to get the shots, or to what extent they are even needed, given that the virus has so far proved less deadly than feared..."

China’s Sinovac Enters Race for Flu Vaccine

Reuters
June 15, 2009
"Chinese vaccine maker Sinovac Biotech Ltd hopes to put its H1N1 vaccine through its first clinical trial by the end of July, as pharmaceutical firms race to put vaccines against the new flu virus into commercial production. Workers at Sinovac's laboratory in Beijing readied thousands of chicken eggs to grow the H1N1 virus on Monday, after the World Health Organization declared a pandemic last Thursday and warned governments to prepare for a long battle against the virus. On Friday, Novartis AG said it expected its H1N1 vaccine to be available by autumn after it produced a first batch for testing and clinical trials..."

Swiss Drugmaker Novartis Says Produces First Batch of Swine Flu Vaccine Grown in Cells

Reuters
June 15, 2009
"Swiss pharmaceuticals company Novartis AG said Friday it has successfully produced a first batch of swine flu vaccine weeks ahead of expectations. The vaccine was made in cells, rather than grown in eggs as is usually the case with vaccines, the company said..."

Swine Flu Declaration Will Speed Work on Vaccine

Los Angeles Times
June 12, 2009
"One immediate effect of the declaration of an H1N1 flu pandemic will be to speed the production of a vaccine against the new virus, but it will be fall at the earliest before the first doses are available. Scientists have encountered some problems in paving the way for such a vaccine. The H1N1 virus grows more slowly in eggs than the seasonal flu virus does, so it has taken longer than expected to prepare the seed stocks of virus that manufacturers will use to start production. But all have now received the starting material, which will allow them to begin full-scale efforts at production, according to Dr. Marie-Paule Kieny of the World Health Organization. Some companies that do not manufacture a seasonal flu vaccine have already started growing the virus, she said, and others will do so as soon as they finish their current vaccine runs, probably within the next week or two. But it is not yet clear whether the slow-growth problems encountered in producing the seed stock will carry over into production..."

WHO: Full Pandemic Flu Vaccine Production To Start In 2 Weeks

Wall Street Journal
June 11, 2009
"The World Health Organization Thursday said vaccine makers should continue producing shots to protect against the common flu, a process that will take another two weeks, and then start producing a vaccine to combat the (A) H1N1 swine flu virus. Vaccine makers have now received the seed virus that will allow them to start developing the vaccine. The first doses of a pandemic vaccine could be available in September, but supply will be limited, Margaret Chan, WHO's director general, told journalists at a news briefing..."

WHO Declares Swine Flu Pandemic

VOA News
June 11, 2009
"The World Health Organization has declared the first influenza pandemic in more than 40 years, as infections of the H1N1 swine flu virus continue to spread. WHO Director-General Margaret Chan announced Thursday that the U.N. agency is raising the pandemic alert level from Phase 5 to the maximum Phase 6 following a meeting of experts in Geneva. Officials note that declaring a pandemic does not mean the disease has become more severe, but that there is an increasing number of infections in different geographical locations..."

Flu Pandemic? U.S. Has Been There for Weeks

Reuters
June 11, 2009
"The World Health Organization may have just declared a pandemic of the H1N1 flu virus, but the United States has been acting as if a pandemic was under way for weeks, health officials said on Thursday. The new swine flu virus was first identified in two U.S. children in April and by the time the news was out, it had already begun spreading. CDC experts estimate that hundreds of thousands of people are likely infected in every state..."

H1N1 Flu Vaccine a Step Closer as Firms Test Vaccines

Reuters
June 10, 2009
"Drugmakers are on track to have a vaccine against the new H1N1 strain of flu ready for the northern hemisphere autumn after receiving seed virus samples, company officials said on Wednesday. Sanofi-Aventis, GlaxoSmithKline, Novartis and Solvay all said their vaccine teams had obtained the new influenza A (H1N1) seed virus within the past fortnight, enabling them to begin the production process. What is still unclear, however, is how much vaccine they will be able to manufacture, since this depends on how easily the new virus strain grows within a commercial production environment..."

More Cases of Flu in Egypt and Lebanon Peninsula (Qatar)

June 9, 2009
"Five New Cases of Foreigners Infected with Swine Flu Were Discovered at a Cairo University Dormitory Yesterday. Egypt's health ministry said, bringing the total number of cases there to 7. Lebanon also discovered 5 new cases of swine flu but they were under control, the health ministry said, bringing the total number of cases there to 8..."

WHO Says Swine Flu Pandemic 'Very Close,' Expresses Concerns About Australia And Canada

Los Angeles Times
June 9, 2009
"The World Health Organization said Tuesday a spike in swine flu cases in Australia may push it to finally announce the first flu pandemic in 41 years. It also expressed concern about an unusual rise in severe illness from the disease in Canada. WHO's flu chief Keiji Fukuda said the agency wanted to avoid "adverse effects" if it announces a global outbreak of swine flu. Fukuda said people might panic or that governments might take inappropriate actions if WHO declares a pandemic..."

Bipartisan WMD Panel Criticizes Obama Plan to Fund Flu Vaccine

Washington Post
June 8, 2009
"President Obama's contingency plan to help finance production of a swine flu vaccine with funds set aside to develop defenses against biological attacks would weaken the nation's preparedness for terrorism, the leaders of a bipartisan commission on weapons of mass destruction said yesterday..."
Avian Flu Fears Said to Help U.S. Prepare for Swine Flu
New York Times
June 5, 2009
"Six years of worrying about bird flu did much to prepare the United States for the current swine flu outbreak, federal officials and an independent monitoring group said Thursday, but they cautioned that there were still gaps in planning. After the H5N1 avian flu emerged widely in Asia in 2003, killing about 60 percent of those infected by it, many countries took steps to head off the crisis that would emerge if that virus were to acquire the ability to jump easily from human to human. It has not, but a number of the measures were helpful. These are some of them: The federal government stockpiled 50 million courses of Tamiflu. New vaccine factories were opened. Pandemic plans were written, and emergency drills were held..."
City Reports Eighth Death Connected With Swine Flu
New York Times
June 5, 2009
"New York City's Department of Health and Mental Hygiene has confirmed an eighth death linked to swine flu, the first of a person older than 65, officials said Friday. Jessica Scaperotti, a spokeswoman for the department, declined to release further identifying details, but she said the victim had underlying complications that increased the risk of death. Health officials have said such complications include being over 65 or under 2, having respiratory or immune system problems or being obese, among others.?.."
Officials Don't Track All Possible Swine Flu Cases: Only a third of 266 samples submitted here were tested
Columbus Dispatch
June 5, 2009
"Just because someone has swine flu doesn't mean that public-health workers monitoring the outbreak will track the case. Recently, a test at Nationwide Children's Hospital showed that an 11-year-old girl from suburban Columbus had influenza A, raising the probability that she had swine flu..."

Contra Costa County Child Infected with Swine Flu Dies

Los Angeles Times
June 4, 2009
"An elementary school-aged child infected with the H1N1 swine flu virus in central Contra Costa County has died, health officials said Thursday. It was not immediately clear whether the child died from the flu, a secondary bacterial infection the child also suffered from, or another cause..."
Chicago Swine Flu Death: New mom dies of flu a day after giving birth; woman, 20, had other underlying medical conditions; baby is in neonatal ICU

June 4, 2009

"Chicago woman became the fourth person in the state to die of the H1N1 swine flu a day after she gave birth, officials said Wednesday. The latest death was a 20-year-old woman from Chicago who died Saturday at the University of Illinois Medical Center, said Sherri McGinnis Gonzalez, a hospital spokeswoman. The woman was admitted to the hospital May 23 with flulike symptoms. Her condition quickly deteriorated, and her baby, a 27-week fetus, was delivered by Caesarean section on Friday, officials said..."
2nd Pa. Swine Flu Death Reported in Philadelphia?

Philadelphia Inquirer

June 4, 2009
"A Philadelphia woman has become the second Pennsylvanian to die from swine flu. Health department officials say the 26-year-old woman died Sunday. Philadelphia Department of Public Health spokesman Jeff Moran says the woman was very ill when she was hospitalized. The state's first swine flu death happened last week when a 55-year-old woman from Berks County died. At least 29 people have died nationwide from the H1N1 influenza outbreak..."
May 2009
Talk of 'Underlying Conditions' May Add to Flu Worries
New York Times
May 28, 2009
"In announcing this week that swine flu had been implicated in the deaths of two more New Yorkers, the city's health commissioner, Dr. Thomas R. Frieden, added a by-now familiar caveat: Both of them, he said, had ''underlying conditions." He went on to enumerate a list of conditions that could aggravate the effects of swine flu and that characterize a large portion of New York's population: diabetes, asthma, heart disease, lung disease, a weakened immune system and, possibly, obesity. He did not even mention three other risk factors that alone apply to more than 1.2 million New Yorkers and 50 million Americans: pregnancy, being younger than 2, or being older than 65..."
Swine Flu, with 63 More Confirmed Cases, Closes Boston's Biggest Charter School
Boston Globe
May 27, 2009
"Public health authorities in Boston announced that they are temporarily closing the city's biggest charter school, Boston Renaissance, for a week because of a suspected outbreak of swine flu. Classes are suspended at the Theatre District school starting today and are expected to resume June 4. The closing was prompted by an unusually high number of absences in recent days, the Boston Public Health Commission said. Boston Renaissance is the eighth public or private school in the city to shut down because of swine flu fears..."
China Quarantines Teens, Teachers from Md.
Washington Post
May 27, 2009
"Twenty-one students and three teachers from a Silver Spring private school who flew last week to China for a weeklong tour have been confined to their hotel rooms, quarantined for possible exposure to swine flu during their flight from the United States. The group arrived in Guizhou province in southwestern China on Friday for an "extended study week," one of several such excursions from the Barrie School, which stresses experiential learning. Government officials quarantined the students and chaperons at a hotel in the city of Kaili because a passenger on the plane was suspected of having swine flu..."

Op-ed: Preparing Ourselves for the Next Epidemic

Oregonian
By Jay Nelson, director of OHSU's Vaccine and Gene Therapy Institute
May 27, 2009
"While it's still hard to tell just how big the H1N1 (also known as swine flu) outbreak will be, it has already highlighted some urgent needs for our country. We must continue to improve our methods for rapidly detecting and tracking outbreaks. We must improve communications between international, national, state and local health officials. We must also use our limited research resources to improve and speed up vaccine development. As a scientist who has devoted most of my professional career to researching infectious disease, I know there is still an enormous amount of work to accomplish before the next epidemic comes. How serious is the threat? Consider this: Each year up to 20 percent of the American population gets the common flu. More than 200,000 people are hospitalized due to complications and about 36,000 people die annually from flu-related causes. Now imagine the impact and casualties from a more serious outbreak..."
Swine Flu Spreads in Australia
Voice of America
May 27, 2009
"The number of H1N1 flu cases in Australia has doubled in the past day to 59. The federal government has warned that the H1N1 influenza A virus is spreading fast. Health experts say its rapid transmission coincides with the southern hemisphere's traditional winter flu season. The H1N1 flu has been confirmed in most Australian states and territories. The epicenter of the outbreak is in Victoria, where a group of children are among those being treated. Virus origin unknown. Tests have yet to reveal if the infections in Australia have been imported from other countries or whether the virus has started to spread among those who have not traveled overseas..."

CDC: H1N1 Flu Infections Slowing In Most Parts of US

Wall Street Journal
May 26, 2009
"Centers for Disease Control and Prevention says number of outpatient visits for influenza-like illnesses declined in most part of US last week; states in New England along with New York and New Jersey are still seeing elevated levels of H1N1 influenza activity..."
Shifting Interest on Flu? It's Fishy; Study of Twitter Says Reactions Swing Quickly
Chicago Tribune
May 26, 2009
"As two Stanford University researchers described their experience watching public reactions in the initial days of the H1N1 flu outbreak, it sounded like one of those nature films in which tiny fish dart back and forth in perfect unison -- thousands of individuals behaving as if they were one body. But what the researchers were watching was in cyberspace, and instead of schools of fish, they were tracking thousands of Twitter-posts pouring into an Internet site in response to shifting news developments on the flu. With every twist and turn of the flu reports, the mass of Twitters swung in near perfect unison, the researchers noticed, even though the individual Twitterers had no contact with each other outside the Web site..."
U.S. to Spend $1 Billion on H1N1 Flu Vaccine Production
Wall Street Journal
May 24, 2009
"Health and Human Services Secretary Kathleen Sebelius said Friday the U.S. will spend $1 billion to start the process of making an H1N1 influenza vaccine. The money, which comes from funds already set aside for pandemic influenza, will fund new and existing contracts with influenza vaccine makers such as Sanofi Aventis SA, GlaxoSmithKline and Novartis..."
The Next Steps for Swine Flu: Predictions, Protection and Prevention
New York Times
May 22, 2009
"Federal health officials will probably recommend that most Americans get three flu shots this fall: one regular flu shot and two doses of any vaccine made against the new swine flu strain. Having had annual flu shots for the last several years gives 'little or no immune benefit' against the new virus, the officials said on Thursday as they released more details of blood tests briefly described on Wednesday..."
U.S. Says People Born Before 1957 May Have Some Immunity to New Virus Strain
New York Times
May 21, 2009
"Confirming the first impressions of many American and Mexican doctors, federal health officials said on Wednesday that people born before 1957 appear to have some immunity to the swine flu virus now circulating. Tests on blood serum from older people showed that they had antibodies that attacked the new virus, Dr. Daniel Jernigan, chief flu epidemiologist at the Centers for Disease Control and Prevention, said in a telephone news conference...."
Survey Finds Link Between Obesity and Flu Severity
Washington Post
May 20, 2009
"A recent Centers for Disease Control and Prevention (CDC) survey of the 30 people hospitalized in California due to the swine flu shows that about 67 percent had an underlying medical condition. According to the report, 11 people had a lung condition, six had an immune disorder, five had heart disease, another five were pregnant, four had diabetes, and another four were obese..."
Flu signs shutter Boston Latin Nearby Winsor also halts classes
Boston Globe
May 20, 2009
"Boston's biggest public school, Boston Latin, will be shuttered for a week in hopes of halting a suspected outbreak of swine flu, city authorities said yesterday. The decision came after more than 250 students called in sick or were sent home because of respiratory symptoms. In a hastily arranged City Hall press conference, Mayor Thomas M. Menino, flanked by his top health and school administrators, acknowledged the move was inconvenient for Latin's 2,400 students and their families..."
U.S. Officials Consider Bumping Up Flu Shot Season
Reuters
May 20, 2009
"U.S. health officials said on Wednesday they are considering starting the vaccination campaign for seasonal flu earlier this year to make room for a possible second round of shots against the new H1N1 flu. The United States also reported its eighth death from the new swine flu virus, in a patient in Arizona. 'If possible we do want to have an earlier rollout of seasonal vaccine,' Dr Daniel Jernigan of the U.S. Centers for Disease Control and Prevention told reporters in a telephone briefing..."
'We Are Not Out of the Woods' with New Flu, CDC Warns
CNN
May 19, 2009
"Health officials say the H1N1 virus, commonly known as the swine flu, is likely to cause more illnesses and deaths in the United States, even though much of the initial anxiety has eased. A researcher investigates swine flu at the Centers for Disease Control and Prevention in Atlanta, Georgia. The Centers for Disease Control and Prevention reported higher levels of flu activity than the average for mid-May and an unusual number of outbreaks in schools. Some clinics reported high numbers of respiratory diseases more commonly seen during the peak of flu season. "We do think that the way the virus is spreading in the U.S., we are not out of the woods, and the disease is continuing," said Dr. Anne Schuchat, interim deputy director for science and public health program at the CDC in a news conference this week..."
Options, and Hurdles, in Speeding Vaccines
New York Times
May 19, 2009
"While a universal flu vaccine would be ideal, the world's best hope for now might be to speed up the production of strain-specific vaccines. The World Health Organization estimates that the world has the capacity to produce one billion to two billion doses of a vaccine against the new swine flu virus in one year. That would leave most of the world's population dangerously unprotected if the virus, known as H1N1, leads to a pandemic..."
The Slippery Slope From Fear to Panic
New York Times
May 19, 2009
"Could a reason for the panicky reaction to the swine flu outbreak be that it diverted our attention, however briefly, from the devastating effects of the global financial crisis, not to mention the myriad chronic health issues that threaten millions of lives? Or is it simply human nature to overreact to threats over which we have little control? 'The fact is that we love to be scared,' argue two British statisticians, Simon Briscoe and Hugh Aldersey-Williams, in 'Panicology,' published in the United States this year by Skyhorse Publishing..."
A Long Search for a Universal Flu Vaccine
New York Times
May 19, 2009
"Scientists and vaccine manufacturers are working on a universal flu vaccine, with a goal of providing at least several years of protection against seasonal and pandemic flu strains. A universal vaccine would eliminate the need for scientists to guess which strains will be dominant during the upcoming flu season, and it would make vaccination more affordable for countries with limited funds for immunization campaigns. However, some experts believe a universal flu vaccine would be a supplement to the seasonal flu vaccine, rather than a replacement. Proteins on the outside of the flu virus that come in contact with antibodies do not vary as much as those on the inside, but researchers working on a universal flu vaccine are targeting the M2 protein that sticks out of the virus..."
New York Reports Its First Swine Flu Death
New York Times
May 18, 2009
"An assistant principal at a New York City public school died of complications from swine flu in an intensive care unit of a Queens hospital on Sunday night, the first death in New York State of the flu strain that has swept across much of the world since it was first identified in April. Hours before the death of the assistant principal, Mitchell Wiener, city officials announced that five more Queens schools had closed. On Friday, Dr. Daniel Jernigan, head of flu epidemiology for the federal Centers for Disease Control and Prevention, said there had been 173 hospitalizations and 5 deaths reported to the agency. But he emphasized that most cases in the United States —  possibly "upwards of 100,000"  — were mild. In Japan, the number of swine flu cases soared over the weekend, and authorities closed more than 1,000 schools and kindergartens..."

New Virus Appears to Be a Factor in Extended Flu Season

Washington Post
May 16, 2009
"More than half of the states are reporting higher levels of flu-like illness when the respiratory disease should be disappearing, and about half of the people with flu are testing positive for the new swine flu virus. As a precaution in the event of a widespread outbreak, Britain, France, Belgium and Finland have collectively placed orders for 127 million doses of a vaccine that GlaxoSmithKline will develop. The vaccine will include an adjuvant that boosts the body's immune response, and the ingredient is not licensed by the U.S. Food and Drug Administration (FDA)..."
Analysis of Flu Virus Could Lead to Better Vaccines
Science Daily
May 13, 2009
"Researchers from Princeton University suggest that a phenomenon known as antibody interference may help scientists develop a more effective flu vaccine. The study is described in the May 11 online edition of the Proceedings of the National Academy of Sciences. In antibody interference, a virus prompts the creation of different types of antibodies, which may sometimes crowd each other out in an attempt to attach themselves to a virus' surface. Antibodies that are less effective at protecting the body against a specific virus are often better able to attaching to the virus, which blocks the more effective antibodies..."
Race for Pandemic Vaccine
Financial Times
May 12, 2009
"The World Health Organization (WHO) says requests for wild type virus samples of the A (H1N1) virus to prepare a pandemic vaccine have been received from major vaccine manufacturers Novartis, GlaxoSmithKline, and Sanofi-Aventis, with samples also being sent to MedImmune, Baxter, CSL, Solvay, Microgen, Nobilon International, Omnivest Vaccines, and Vivaldi. The WHO plans to make a recommendation in the coming weeks on whether a pandemic vaccine is needed and how to go about producing one. First, health officials must determine whether this flu strain is as severe as the seasonal flu, which results in 500,000 deaths annually..."

Other Illness May Precede Worst Cases of Swine Flu

New York Times
May 9, 2009
"Individuals infected with the H1N1 flu who have underlying conditions, such as diabetes or heart disease, are at greater risk of hospitalization or death, according to experts from the World Health Organization and Centers for Disease Control and Prevention (CDC). These preliminary observations are based on discussion of about 40 deaths in Mexico and half of the 57 hospitalizations in the United States. Most of the Americans hospitalized had an additional health problem, said Dr. Richard E. Besser, acting director of the CDC. Seven of the cases involved asthma, which has become more common in the United States, along with diabetes and obesity..."
Vaccine Would Be Spoken For
Washington Post
May 7, 2009
"No final decision has been made yet to produce a vaccine against the H1N1 swine flu virus, but some wealthier countries reportedly have made "pre-production contracts" that claim substantial quantities of the vaccine, if made. The worldwide capacity for making a pandemic vaccine ranges between 1 billion and 2 billion, and the United States' preexisting contracts allow it to purchase at least 600 million of those doses. This would provide the U.S. population of about 305 million with almost two doses for each person, as immunity may need two shots to be stimulated against the swine flu strain. A panel of scientific experts are expected to meet next week to advise the World Health Organization on whether it should ask manufacturers to begin large-scale vaccine production and how to provide more equal access to the vaccine for developing countries..."
Officials Note Youth of Serious Flu Cases
New York Times
May 7, 2009
"Dr. Richard Besser, acting director of the Centers for Disease Control and Prevention, says the swine flu has caused only 35 hospitalizations in the United States, but there are concerns that the median age of these patients is 15 years. In contrast, the elderly, infants, and the sick account for a majority of deaths each year from the seasonal flu. Besser says teenagers may be more prone to infection because a bulk of the early cases were tied to students who traveled to Mexico for spring break. Additionally, individuals born prior to 1957 may have some immunity, as the H1N1 seasonal flu was replaced by the H2N2 "Asian flu" strain that year..."
U.S. May Add Shots for Swine Flu to Fall Regimen
Washington Post
May 6, 2009
"The Obama administration is considering an unprecedented fall vaccination campaign that could entail giving Americans three flu shots -- one to combat annual seasonal influenza and two targeted at the new swine flu virus spreading across the globe. If enacted, the multibillion-dollar effort would represent the first time that top federal health officials have asked Americans to get more than one flu vaccine in a year, raising serious challenges concerning production, distribution and the ability to track potentially severe side effects..."
Cooking Up Millions of Viruses for a New Vaccine
New York Times
May 6, 2009
"As soon as Doris Bucher learned that a new strain of swine flu had turned up in the United States, she e-mailed the Centers for Disease Control and Prevention offering to send materials that might be useful in making a vaccine. Her colleagues at the C.D.C. had a better idea. Less than a week later, they sent a sample of the new type of virus, influenza A(H1N1), to Dr. Bucher, an associate professor of microbiology and immunology at New York Medical College. Dr. Bucher, a cheerful, fast-talking scientist who has been involved in flu research for 40 years, runs a laboratory here in Westchester County that is highly regarded for its skill at turning flu viruses into 'seed stock’ — a form of the virus that will grow rapidly in eggs so that drug companies can use it to make hundreds of millions of doses of vaccine..."
Swine Flu School Closures Not Recommended by U.S.
Bloomberg
May 5, 2009
"Swine flu shouldn’t close schools unless so many students or teachers get sick that the institutions can’t function, the U.S. Centers for Disease Control and Prevention said, reversing earlier advice. The agency today changed its recommendation that schools consider closing if they suspect swine flu. That advice led to the closure today of at least 726 schools in 24 states and the District of Columbia, keeping about 468,000 students out of class, according to the U.S. Education Department..."
Flu, Mostly Mild, Has Spread Across U.S.
New York Times
May 4, 2009
"Swine flu has become widespread in the United States, with 226 cases in 30 states and more expected to turn up in additional states in the next few days, federal health officials said Sunday. 'I think it’s circulating all over the U.S.,' Dr. Anne Schuchat, the interim deputy director for science and public health at the Centers for Disease Control and Prevention, said in a news conference..."
Swine Flu Breaking News Update: Global case update, eyeing phase 6, probable cases, southern hemisphere viruses, WHO gathers clinical experts
CIDRAP
May 4, 2009
"The World Health Organization (WHO) reported 1,085 confirmed cases of influenza A/H1N1 (swine flu) and 26 deaths in 21 countries as of 18:00 GMT (noon US EST) today, up from 985 cases in 20 countries reported earlier in the day. Mexico has reported 590 confirmed cases and 25 deaths. The WHO's latest total reflects today's updated US numbers from the Centers for Disease Control and Prevention (CDC), which stand at 286 cases and 1 death..."
WHO Says Existing Vaccine Little Use Against New Flu
Reuters
May 1, 2009
"Testing shows that the current vaccine against seasonal flu would not be effective against the new H1N1 strain, the World Health Organization (WHO) said Friday. Marie-Paule Kieny, director of the WHO's initiative for vaccine research, said that making a successful vaccine against the new strain is possible, but it would take between four and six months for it to be available. Samples needed to make a vaccine would be ready for manufacturers by mid to late May..."
April 2009
Swine Flu Case in Spain May Point to Global Pandemic, WHO Says
Bloomberg
April 30, 2009
"A swine-flu patient in Spain who hadn't traveled to Mexico may signal a new front of the outbreak, potentially heralding the first influenza pandemic in 41 years. The World Health Organization raised its six-tier alert to 5, the second-highest, and said a pandemic declaration may come soon. It urged countries to make final preparations to deal with a virus that may sweep across the globe. The WHO has confirmed 154 cases in nine countries, and hundreds of people are being tested for the virus from Australia to New York. Eight of those known to have had swine flu have died, though many more may be carrying the virus and not getting seriously ill, the WHO said..."
W.H.O. Alert Says a Global Spread of Flu Is Likely
New York Times
April 30, 2009
"For the first time since it rolled out the pandemic warning system in 2005, the World Heath Organization (WHO) has increased the alert level to Phase 5, which is the second-highest level. The increase is in response to the ongoing spread of the swine flu in the United States and Mexico, with the number of U.S. cases rising to 91 in 10 states from 64 in five states on April 28, according to the Centers for Disease Control and Prevention (CDC). The first swine flu-related death in the United States was reported on Wednesday, a 23-month-old child from Mexico who was being treated in Houston. WHO Director-General Dr. Margaret Chan has urged every country to activate their pandemic preparedness plans right away, while at the same time encouraging people to remain calm. Dr. Anthony Fauci of the National Institute of Allergy and Infectious Diseases says the lack of background immunity in the population is a major concern and, along with human-to-human transmission, could lead to a pandemic..."
Officials Face a Tough Decision over Ordering Vaccine
Wall Street Journal
April 30, 2009
"Global health officials trying to gauge the severity of the swine-flu outbreak face a tough call on how quickly to move on creating a vaccine for the new virus. As confirmed cases of the new A/H1N1 flu virus mount and spread around the world, health officials must balance the desire to stop the spread quickly with some serious risks of moving too fast. Even with a full push, it would take months to get a vaccine ready, and the effort could force drug companies to cut corners or reduce production of regular flu vaccine needed for the winter. But waiting too long could allow the swine-flu virus to have a much more deadly impact. Work has already begun on a vaccine. The U.S. Centers for Disease Control and Prevention in Atlanta has the basic components for a swine-flu vaccine, and is studying the makeup of the virus to better understand a central mystery: why it has caused serious illness and deaths in Mexico but generally milder symptoms elsewhere."
Swine Flu Vaccine May Be Months Away, Experts Say
New York Times
April 29, 2009
"Federal officials said it would take until January, or late November at the earliest, to make enough vaccine to protect all Americans from a possible epidemic of swine flu. And beyond the United States and a few other countries that also make vaccines, some experts said it could take years to produce enough swine flu vaccine to satisfy global demand. Although production is much faster than would have been possible even a few years ago, it still may not be in time to avert death and illness if the virus starts spreading widely and becomes more virulent, some experts said. In this country, the biggest problem is that despite years of effort, the country is still relying on half-century-old technology to make the flu vaccines..."
Obama Says Flu-Hit Schools May Need to Close
NPR
April 29, 2009
"President Barack Obama suggested Wednesday that school closings may be necessary in an escalating global health emergency that claimed the first death in the United States — a 23-month-old child in Texas. Obama said educators with confirmed swine flu infections should weigh shutting down classes if conditions worsen..."
Vaccine Makers Await Critical Swine Flu Samples; Swine Flu Won't Be in Seasonal Flu Vaccines
April 29, 2009
"As the World Health Organization (WHO) today acknowledged the spreading swine influenza virus by moving the pandemic threat awareness level up one notch to 5, the U.S. Centers for Disease Control (CDC) worked to get drug companies the materials they need to create a vaccine. Meanwhile, the U.S. Department of Health and Human Services (HHS) said it is unlikely that any new swine flu vaccine would be included in the batches of seasonal influenza vaccines already in production for the typical August vaccine ship date..."
The Naming of Swine Flu, a Curious Matter
New York Times
April 29, 2009
"What to call the new strain of flu raising alarms around the world has taken on political, economic and diplomatic overtones. Pork producers question whether the term "swine flu" is appropriate, given that the new virus has not yet been isolated in samples taken from pigs in Mexico or elsewhere. While the new virus seems to be most heavily composed of genetic sequences from swine influenza virus material, it also has human and avian influenza genetic sequences as well, according to the Centers for Disease Control and Prevention in Atlanta..."
Op-ed: Understanding Swine Flu
Wall Street Journal
April 29, 2009
"The trouble starts in poor countries where too many people live in proximity to pigs and poultry. The extent and impact of the swine flu epidemic, which appears to have originated in Mexico and spread rapidly to a dozen countries and parts of the U.S., is still unknown. The epidemiology of such disease outbreaks is rather like a jigsaw puzzle, and we are now at the stage where the picture is intriguing even if we're not sure what we're seeing..."
Swine Flu Kills First Victim in U.S.
Los Angeles Times
April 29, 2009
"A 23-month-old child in Texas has become the first swine flu fatality in the U.S. The child was one of six people with confirmed cases of swine flu in the Lone Star State, in addition to the 10 confirmed cases in California, two in Kansas, and one in Ohio, according to the latest figures from the Centers for Disease Control. Another 45 cases have been confirmed in New York City. That brings the total number of confirmed cases in the U.S. to 64. Meanwhile, President Obama is calling for action to contain the spread of the virus. He noted that health authorities across the country need to be diligent in monitoring the outbreak of swine flu, and said that schools with suspected cases of the virus should follow the advice of public health officials and consider closing temporarily. Obama has also asked for $1.5 billion to deal with swine flu, and has put his new Health and Human Services Secretary, Kathleen Sebelius, to work on dealing with the outbreak..."
Past Epidemics Have Current Import
Boston Globe
April 28, 2009
"In responding to the swine flu, public health officials can take some lessons from previous outbreaks. Because epidemics are unpredictable, each outbreak must be examined 'on its own terms,' said Dr. Harvey Fineberg, president of the Institute of Medicine. An outbreak of swine flu emerged at Fort Dix, N.J., in 1976, with more than 200 soldiers infected, including one death. Fearful of greater spread of the virus, more than 40 million Americans were vaccinated, though that flu cluster never did move beyond Fort Dix. Analysis of the 1918 flu pandemic has also helped scientists identify strategies to control the spread of disease, including shutting down schools and isolating those who are sick. The most important thing to examine at the beginning of an outbreak, experts say, is the mortality rate and knowing how it is being transmitted..."
US Wants Ingredient in Swine Flu Vaccine by May
Seattle Times
April 28, 2009
"U.S. scientists hope to have a key ingredient for a swine flu vaccine ready in early May, but are finding that the novel virus grows slowly in eggs — the chief way flu vaccines are made. Even if all goes well, it still will take a few months before any shots are available for the first required safety testing, in volunteers. 'We're working together at 100 miles an hour to get material that will be useful,' Dr. Jesse Goodman, who oversees the Food and Drug Administration's swine flu work, told The Associated Press. Using samples of the new swine flu, taken from people who fell ill in Mexico and the U.S., scientists are engineering a strain that could trigger the immune system without causing illness. 'We're about a third of the way' to that goal, Dr. Ruben Donis of the Centers for Disease Control and Prevention said in an interview Tuesday..."
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