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Experts from the CDC Answer Questions About Vaccines

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From the National Center for Immunization and Respiratory Diseases at CDC, introducing
Medical Officer Andrew T. Kroger, MD, MPH
Nurse Educator Donna L. Weaver, RN, MN
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QUESTION: My patient is a 14-year-old girl who has received one dose of bivalent HPV vaccine (HPV2, Cervarix, GlaxoSmithKline) and now wants to change over to quadrivalent HPV vaccine (HPV4, Gardasil, Merck). What is the recommendation to be followed?
ANSWER: You can complete the series with HPV4 (two more doses), which will assure protection against HPV types 16 and 18 (those types most likely to cause cervical and other cancers and that are in both HPV2 and HPV4). However, receiving only two doses of HPV4 may provide less protection against genital warts than the usual 3 doses. More information is available at www.cdc.gov/mmwr/pdf/rr/rr6305.pdf.
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